| Identification |
|---|
| BMDB Protein ID
| BMDBP00345 |
| Secondary Accession Numbers
| None |
| Name
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| NDUFS8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 29 |
| Locus
| Not Available |
| SNPs
| NDUFS8 |
| Gene Sequence
|
>639 bp
ATGCGCTGCCTGACCATGCCCATGCTGCTTCGGGCCCTGGCCCAGGCCCAGGCCGCACGT
GCAGGGCATGCAAGTGTCCGCGGCCTCCACAGCAGCGCAGTGGCAGCCACCTACAAATAT
GTGAACCTGCGGGAGCCCTCGATGGACATGAAGTCGGTGACTGACCGGGCAGCACAGACC
CTGCTGTGGACCGAGCTCATCCGAGGCCTGGGCATGACCCTGAGCTACCTGTTCCGTGAG
CCCGCCACCATCAACTACCCGTTTGAGAAGGGCCCGCTGAGTCCGCGCTTCCGCGGGGAG
CACGCACTGCGCCGTTACCCGTCCGGGGAGGAGCGCTGCATCGCCTGCAAGCTCTGTGAG
GCCGTCTGCCCGGCCCAGGCCATCACCATCGAGGCTGAGCCGCGGGCCGATGGCAGCCGC
CGGACCACGCGCTATGACATCGACATGACCAAGTGCATCTACTGCGGCTTCTGCCAGGAG
GCCTGCCCCGTGGACGCCATTGTGGAGGGCCCCAACTTCGAGTTCTCCACCGAGACGCAC
GAGGAGCTGCTGTACAACAAGGAGAAGCTGCTCAACAACGGGGACAAGTGGGAGGCCGAG
ATCGCTGCCAACATCCAGGCCGACTACCTTTACCGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 212 |
| Molecular Weight
| 23896.0 |
| Theoretical pI
| 6.87 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 6-27
- 39-58
- 84-105
- 117-134
- 140-160
- 172-191
- 245-266
- 272-294
- 362-386
- 406-432
- 453-472
- 484-502
- 586-604
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
MRCLTMPMLLRALAQAQAARAGHASVRGLHSSAVAATYKYVNLREPSMDMKSVTDRAAQT
LLWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCE
AVCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETH
EELLYNKEKLLNNGDKWEAEIAANIQADYLYR
|
| External Links |
|---|
| GenBank ID Protein
| AAA30664.1 |
| UniProtKB/Swiss-Prot ID
| P42028 |
| UniProtKB/Swiss-Prot Entry Name
| NDUS8_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| M58717 |
| GeneCard ID
| NDUFS8 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
