Identification
BMDB Protein ID BMDBP00348
Secondary Accession Numbers None
Name NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Synonyms Not Available
Gene Name NDUFV1
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 29
Locus Not Available
SNPs NDUFV1
Gene Sequence
>1395 bp
ATGCTGGCGGCACGGCGGCTGCTCGGCGGGTCGCTCCCCGCGCGGGTGTCTGTGCGATTC
AGCGGCGACACGACAGCGCCCAAGAAAACCTCATTTGGCTCGCTGAAGGACGAAGACCGG
ATCTTCACCAACCTGTATGGCCGCCATGACTGGAGGCTTAAAGGTGCCCAGAGTCGAGGT
GACTGGTACAAGACGAAGGAGATTCTGCTGAAGGGGCCTGACTGGATCCTGGGTGAGGTC
AAGACGTCGGGCTTGCGGGGCCGTGGAGGTGCTGGCTTCCCCACTGGCCTTAAATGGAGC
TTCATGAATAAGCCCTCAGATGGCAGGCCCAAGTATCTGGTGGTGAACGCGGATGAGGGG
GAGCCAGGCACGTGCAAGGACCGAGAGATCATCCGCCACGACCCCCACAAGCTGGTGGAA
GGCTGCCTAGTAGGGGGCCGGGCCATGGGCGCTCGTGCCGCCTACATCTACATCCGCGGG
GAGTTCTACAACGAGGCCTCCAATCTGCAGGTAGCCATCCGAGAGGCCTACGAGGCTGGT
CTGATTGGCAAGAATGCCTGCGGCTCCGGCTACGATTTCGACGTGTTTGTGGTGCGTGGG
GCCGGGGCCTACATCTGCGGGGAGGAGACGGCGCTCATCGAGTCCATCGAGGGCAAACAG
GGCAAGCCCCGCCTGAAGCCGCCTTTCCCTGCAGACGTGGGAGTGTTTGGCTGCCCTACA
ACTGTGGCCAATGTGGAGACTGTGGCCGTGTCCCCTACCATCTGCCGCCGTGGGGGTGCC
TGGTTTGCCAGCTTCGGCCGAGAGCGCAACTCAGGCACCAAACTGTTCAACATCTCTGGC
CACGTCAACAACCCCTGCACCGTGGAGGAGGAGATGTCTGTGCCGCTGAAGGAGCTGATT
GAAAAGCACGCCGGGGGTGTCACGGGTGGCTGGGACAACCTCCTTGCTGTGATCCCTGGC
GGCTCGTCCACCCCGCTGATCCCCAAGTCCGTGTGTGAGACGGTGCTGATGGACTTCGAC
GCGCTGATCCAGGCGCAGACGGGGCTGGGCACGGCTGCCGTGATCGTCATGGACCGCTCG
ACGGACATTGTGAAAGCCATCGCCCGCCTCATCGAGTTCTACAAGCATGAGAGCTGTGGC
CAGTGTACCCCGTGCCGCGAGGGTGTGGACTGGATGAACAAGGTGATGGCCCGCTTTGTG
AGGGGAGATGCCCGGCCGGCAGAGATCGACTCTCTGTGTGAGATCAGCAAGCAGATCGAG
GGCCACACCATCTGCGCCCTGGGCGATGGGGCTGCGTGGCCCGTGCAGGGCCTGATCCGA
CACTTCCGGCCGGAGCTCGAGGAGCGGATGCAGCAGTTTGCCCAGCAGCACCAGGCCAGG
CAAGCAGCTTTCTGA
Protein Properties
Number of Residues 464
Molecular Weight 50652.0
Theoretical pI 8.16
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 20-40
  • 101-126
  • 162-181
  • 202-221
  • 236-254
  • 283-306
Protein Sequence
>NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
MLAARRLLGGSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSRG
DWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEG
EPGTCKDREIIRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAG
LIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPT
TVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNNPCTVEEEMSVPLKELI
EKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALIQAQTGLGTAAVIVMDRS
TDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIE
GHTICALGDGAAWPVQGLIRHFRPELEERMQQFAQQHQARQAAF
GenBank ID Protein AAA30450.1
UniProtKB/Swiss-Prot ID P25708
UniProtKB/Swiss-Prot Entry Name NDUV1_BOVIN
PDB IDs
GenBank Gene ID M58607
GeneCard ID NDUFV1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available