Identification |
BMDB Protein ID
| BMDBP00357 |
Secondary Accession Numbers
| None |
Name
| L-2-hydroxyglutarate dehydrogenase, mitochondrial |
Synonyms
|
Not Available
|
Gene Name
| L2HGDH |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in 2-hydroxyglutarate dehydrogenase activity |
Specific Function
| Not Available |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 10 |
Locus
| Not Available |
SNPs
| L2HGDH |
Gene Sequence
|
>1392 bp
ATGGTACCAGCACTGCGTTACCTGGGCAGTGTCTGCGGACGGGCCCGCGGGATTTTCCCC
GGGGGCTTCTCCGCGGCGCACACACCCGCGTCGGGGAAATCCCGGCTGTTGTGCCAGGGT
GGCCGCAGAGCCAGCACCAGCTCATTTGATATAGTCATTATTGGTGGCGGAATTGTGGGG
CTTGCCTCTGCCAGAGCACTCATCCTGCGACATCCAGCTCTTTCCATTGGTGTTCTGGAG
AAGGAGAAAAATTTAGCTGTTCATCAGACCGGACACAATAGTGGTGTCATACATAGTGGG
ATTTATTATAAACCCGAATCTCTGAAAGCTAAATTATGTGTGCAAGGTGCAGCCCTCATC
TACGAGTACTGTAACCAAAAGGGAATTTCCTACAAGCAATGTGGCAAGCTTATAGTGGCT
GTTGAACAGGAAGAAATTCCCAGACTTCAGGCCCTGTATGAGAGAGGCCTGCAGAATGGT
GTCCAGGGCCTGAGGCTGATCCAGCAGGAGGACATAAAAAAGAAGGAGCCATATTGTAGG
GGTCTAATGGCTATCGATTGTCCCTATACTGGCATCGTGGACTATCGGCAGGTGGCTTTT
TCATTTGCCAAGGATTTCCAAGAAGCAGGTGGCTCTGTTTTGACCAATTTTGAAGTAGAA
GATATTGAAATGGCTAGAGAAAGTCCTTCAAGAAGTAAAGATGGGATGAAATATCCAATC
GTTATAAGGAATACAAAGGGAGAGGAGGTCCGATGTCAGTATGTTGTGACATGTGCGGGA
CTTTACTCAGACCGTATTTCCGAGTTGAGTGGCTGCAATCCCAATCCTCGAATTGTACCA
TTCCGGGGAGATTACCTAGTCTTGAAGCCAGAAAAGCGCTATCTTGTAAAAGGAAATATT
TATCCGGTCCCCGATAGCCGATTTCCTTTCCTAGGAGTTCACTTCACACCAAGGATGGAT
GGCAATATTTGGCTAGGGCCCAATGCAATTCTTGCCTTTAAACGAGAGGGCTACAGACCC
TTTGACTTCAGTGCCAGAGATATTATGGATATAATCATCAAGAGTGGCTTGATTAAACTG
GTGTTCCAGAATTTCTCCTATGGAGTTAATGAAATGTACAAAGCATGTTTTCTCAGTGCA
ACAGTGAAGCACCTTCAAAAGTTTATCCCTGAAATTACTATCAGTGATGTACTTAGAGGC
CCCGCTGGAGTAAGAGCCCAAGCCCTGGATAGGGATGGGAATCTCATAGAAGATTTTGTG
TTTGATGGAGGCGTTGGGGATATTGGAAATCGCATTCTTCATGTGAGGAATGCACCTTCC
CCTGCTGCCACTTCTTCCCTTGCGATTTCTGGAATGATTGCAGATGAAGTGCAACAAAGA
TTTAAATTGTAA
|
Protein Properties |
Number of Residues
| 463 |
Molecular Weight
| 51022.0 |
Theoretical pI
| 9.23 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
- 6-27
- 39-58
- 84-105
- 117-134
- 140-160
- 172-191
- 211-233
- 245-266
- 272-294
- 301-319
- 325-347
- 368-386
- 406-432
- 453-472
- 484-502
- 586-604
|
Protein Sequence
|
>L-2-hydroxyglutarate dehydrogenase, mitochondrial
MVPALRYLGSVCGRARGIFPGGFSAAHTPASGKSRLLCQGGRRASTSSFDIVIIGGGIVG
LASARALILRHPALSIGVLEKEKNLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALI
YEYCNQKGISYKQCGKLIVAVEQEEIPRLQALYERGLQNGVQGLRLIQQEDIKKKEPYCR
GLMAIDCPYTGIVDYRQVAFSFAKDFQEAGGSVLTNFEVEDIEMARESPSRSKDGMKYPI
VIRNTKGEEVRCQYVVTCAGLYSDRISELSGCNPNPRIVPFRGDYLVLKPEKRYLVKGNI
YPVPDSRFPFLGVHFTPRMDGNIWLGPNAILAFKREGYRPFDFSARDIMDIIIKSGLIKL
VFQNFSYGVNEMYKACFLSATVKHLQKFIPEITISDVLRGPAGVRAQALDRDGNLIEDFV
FDGGVGDIGNRILHVRNAPSPAATSSLAISGMIADEVQQRFKL
|
External Links |
GenBank ID Protein
| AAI51578.1 |
UniProtKB/Swiss-Prot ID
| A7MBI3 |
UniProtKB/Swiss-Prot Entry Name
| L2HDH_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC151577 |
GeneCard ID
| L2HGDH |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |