Identification
BMDB Protein ID BMDBP00357
Secondary Accession Numbers None
Name L-2-hydroxyglutarate dehydrogenase, mitochondrial
Synonyms Not Available
Gene Name L2HGDH
Protein Type Enzyme
Biological Properties
General Function Involved in 2-hydroxyglutarate dehydrogenase activity
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 10
Locus Not Available
SNPs L2HGDH
Gene Sequence
>1392 bp
ATGGTACCAGCACTGCGTTACCTGGGCAGTGTCTGCGGACGGGCCCGCGGGATTTTCCCC
GGGGGCTTCTCCGCGGCGCACACACCCGCGTCGGGGAAATCCCGGCTGTTGTGCCAGGGT
GGCCGCAGAGCCAGCACCAGCTCATTTGATATAGTCATTATTGGTGGCGGAATTGTGGGG
CTTGCCTCTGCCAGAGCACTCATCCTGCGACATCCAGCTCTTTCCATTGGTGTTCTGGAG
AAGGAGAAAAATTTAGCTGTTCATCAGACCGGACACAATAGTGGTGTCATACATAGTGGG
ATTTATTATAAACCCGAATCTCTGAAAGCTAAATTATGTGTGCAAGGTGCAGCCCTCATC
TACGAGTACTGTAACCAAAAGGGAATTTCCTACAAGCAATGTGGCAAGCTTATAGTGGCT
GTTGAACAGGAAGAAATTCCCAGACTTCAGGCCCTGTATGAGAGAGGCCTGCAGAATGGT
GTCCAGGGCCTGAGGCTGATCCAGCAGGAGGACATAAAAAAGAAGGAGCCATATTGTAGG
GGTCTAATGGCTATCGATTGTCCCTATACTGGCATCGTGGACTATCGGCAGGTGGCTTTT
TCATTTGCCAAGGATTTCCAAGAAGCAGGTGGCTCTGTTTTGACCAATTTTGAAGTAGAA
GATATTGAAATGGCTAGAGAAAGTCCTTCAAGAAGTAAAGATGGGATGAAATATCCAATC
GTTATAAGGAATACAAAGGGAGAGGAGGTCCGATGTCAGTATGTTGTGACATGTGCGGGA
CTTTACTCAGACCGTATTTCCGAGTTGAGTGGCTGCAATCCCAATCCTCGAATTGTACCA
TTCCGGGGAGATTACCTAGTCTTGAAGCCAGAAAAGCGCTATCTTGTAAAAGGAAATATT
TATCCGGTCCCCGATAGCCGATTTCCTTTCCTAGGAGTTCACTTCACACCAAGGATGGAT
GGCAATATTTGGCTAGGGCCCAATGCAATTCTTGCCTTTAAACGAGAGGGCTACAGACCC
TTTGACTTCAGTGCCAGAGATATTATGGATATAATCATCAAGAGTGGCTTGATTAAACTG
GTGTTCCAGAATTTCTCCTATGGAGTTAATGAAATGTACAAAGCATGTTTTCTCAGTGCA
ACAGTGAAGCACCTTCAAAAGTTTATCCCTGAAATTACTATCAGTGATGTACTTAGAGGC
CCCGCTGGAGTAAGAGCCCAAGCCCTGGATAGGGATGGGAATCTCATAGAAGATTTTGTG
TTTGATGGAGGCGTTGGGGATATTGGAAATCGCATTCTTCATGTGAGGAATGCACCTTCC
CCTGCTGCCACTTCTTCCCTTGCGATTTCTGGAATGATTGCAGATGAAGTGCAACAAAGA
TTTAAATTGTAA
Protein Properties
Number of Residues 463
Molecular Weight 51022.0
Theoretical pI 9.23
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 6-27
  • 39-58
  • 84-105
  • 117-134
  • 140-160
  • 172-191
  • 211-233
  • 245-266
  • 272-294
  • 301-319
  • 325-347
  • 368-386
  • 406-432
  • 453-472
  • 484-502
  • 586-604
Protein Sequence
>L-2-hydroxyglutarate dehydrogenase, mitochondrial
MVPALRYLGSVCGRARGIFPGGFSAAHTPASGKSRLLCQGGRRASTSSFDIVIIGGGIVG
LASARALILRHPALSIGVLEKEKNLAVHQTGHNSGVIHSGIYYKPESLKAKLCVQGAALI
YEYCNQKGISYKQCGKLIVAVEQEEIPRLQALYERGLQNGVQGLRLIQQEDIKKKEPYCR
GLMAIDCPYTGIVDYRQVAFSFAKDFQEAGGSVLTNFEVEDIEMARESPSRSKDGMKYPI
VIRNTKGEEVRCQYVVTCAGLYSDRISELSGCNPNPRIVPFRGDYLVLKPEKRYLVKGNI
YPVPDSRFPFLGVHFTPRMDGNIWLGPNAILAFKREGYRPFDFSARDIMDIIIKSGLIKL
VFQNFSYGVNEMYKACFLSATVKHLQKFIPEITISDVLRGPAGVRAQALDRDGNLIEDFV
FDGGVGDIGNRILHVRNAPSPAATSSLAISGMIADEVQQRFKL
GenBank ID Protein AAI51578.1
UniProtKB/Swiss-Prot ID A7MBI3
UniProtKB/Swiss-Prot Entry Name L2HDH_BOVIN
PDB IDs Not Available
GenBank Gene ID BC151577
GeneCard ID L2HGDH
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available