Showing Protein 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (BMDBP00366)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 9 metabolites
Identification
BMDB Protein ID BMDBP00366
Secondary Accession Numbers
  • BMDBP03145
Name 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
Synonyms Not Available
Gene Name GCAT
Protein Type Enzyme
Biological Properties
General Function Coenzyme transport and metabolism
Specific Function Not Available
Pathways
  • Amino-acid degradation
  • Glycine from L-threonine: step 2/2
  • L-threonine degradation via oxydo-reductase pathway
Reactions
Palmityl-CoA + L-Serine → 3-Dehydrosphinganine + Carbon dioxide details
Acetyl-CoA + Glycine → L-2-Amino-3-oxobutanoic acid + Coenzyme A details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 5
Locus Not Available
SNPs GCAT
Gene Sequence 
>1260 bp
ATGTGGGCTGGCCGCGTCCTGCATGCTGCGCTCTCCCGGGCCCCCCGCGAGAGCCGGGCG
CAGTCAGCGCTGGCTCAGCTGCGTGGCATCCTGGAGGAGGAGCTGGAAAGCATCCGCGGA
GCTGGCACCTGGAAGAGCGAGCGGGTCATCACGTCCCGTCAGGGGCCGCACATCCACGTG
GACGGCGCCCCGGGAGGAATTATTAACTTCTGTGCCAACAACTACCTGGGCCTGAGCAGC
CACCCTGAGGTCATTCAGGCAGGTCTGCGGACCCTAAAGGAGTTTGGAGCCGGCCTTAGC
TCAGTCCGCTTCATCTGTGGCACCCAGAGCATCCACAAAGACCTAGAAGCAAAGATAGCC
CGCTTTCACCAAAGGGAGGATGCCATCCTCTATCCCAGCTGTTTTGATGCCAACACCGGC
CTCTTTGAGGCACTGCTGACTTCGGAGGACGCAGTCCTGTCGGATGAGCTGAACCATGCC
TCCATCATCGATGGCATCCGTCTGTGCAAGGCCCACAAGTACCGCTACCGCCACCTGGAT
ATGGCTGATCTGGAGGCCAAGCTGCAGGAGGCCCAGAAGCATCGGCTGCGCCTGGTGGCC
ACTGATGGGGCCTTTTCCATGGATGGTGACATCGCACCCCTGCAGGAGATCTGCCGCCTT
GCCTCTCAATATGGTGCCTTAGTCTTTGTGGACGAAAGCCACGCCACTGGCTTCCTGGGG
GCCACAGGACGGGGCACAGATGAGCTGCTGGGCGTGATGGACCAAGTCACCATCATCAAC
TCCACACTGGGGAAGGCCCTGGGTGGAGCATCAGGGGGCTACACGACTGGGCCTGGGGCC
CTGGTATCCCTGCTACGGCAGCGTGCCCGGCCCTACCTCTTCTCCAACAGCCTGCCCCCT
GCTGCTGTCGGCTGTGCCTCCAAGGCCCTGGACCTGCTCATGGAGAGCAACGCCATCGTC
CAGTCTATGGCGGCCAAGACCCTGCGATTCCGCAGTCAGATGGAGGCTGCTGGCTTCACC
ATCTCAGGAGCCAATCACCCCATCTGCCCTGTGATGCTGGGTGACGCTCGGCTGGCCTTA
AACATAGCGGATGACATGCTTAAGAGAGGCATCTTTGTCATTGGGTTCAGCTACCCTGTG
GTCCCCAAAGGCAAGGCCCGGATCCGAGTCCAGATCTCAGCAGTGCACAGTGAGGAGGAC
ATTGACCGCTGTGTGGAGGCCTTCGTGGAGGTGGGGCGACTGCACGGCGCGCTGCCTTGA
Protein Properties
Number of Residues 419
Molecular Weight 45166.0
Theoretical pI 7.38
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
MWAGRVLHAALSRAPRESRAQSALAQLRGILEEELESIRGAGTWKSERVITSRQGPHIHV
DGAPGGIINFCANNYLGLSSHPEVIQAGLRTLKEFGAGLSSVRFICGTQSIHKDLEAKIA
RFHQREDAILYPSCFDANTGLFEALLTSEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD
MADLEAKLQEAQKHRLRLVATDGAFSMDGDIAPLQEICRLASQYGALVFVDESHATGFLG
ATGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGALVSLLRQRARPYLFSNSLPP
AAVGCASKALDLLMESNAIVQSMAAKTLRFRSQMEAAGFTISGANHPICPVMLGDARLAL
NIADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGRLHGALP
GenBank ID Protein AAI19871.1
UniProtKB/Swiss-Prot ID Q0P5L8
UniProtKB/Swiss-Prot Entry Name KBL_BOVIN
PDB IDs Not Available
GenBank Gene ID BC119870
GeneCard ID GCAT
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available