Showing Protein Sulfotransferase 1A1 (BMDBP00376)
| Identification | |||||
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| BMDB Protein ID | BMDBP00376 | ||||
| Secondary Accession Numbers |
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| Name | Sulfotransferase 1A1 | ||||
| Synonyms | Not Available | ||||
| Gene Name | SULT1A1 | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Involved in aryl sulfotransferase activity | ||||
| Specific Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk (By similarity). | ||||
| Pathways | Not Available | ||||
| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 25 | ||||
| Locus | Not Available | ||||
| SNPs | SULT1A1 | ||||
| Gene Sequence |
>885 bp ATGGAACTGATCCAGGATACCTCCCGCCCTCCAGCAAAGTATGTGAAGGGCATCCCTCTC ATCAAGTACTTTGCAGAGGCCCTGGGGCCACTGGAGAGCTTTGAAGCCTGGCCTGATGAC TTGCTCATCAGCACCTACCCCAAGTCGGGCACCACCTGGGTAAGCGAGATCCTGGACCTG ATCTACCAGGAGGGTGACCTGGAGAAGTGTCAGAGAGCCCCTGTCTTCTTGCGGGTGCCC TTCCTTGAGTTCAGCGCCCCTGGGGTTCCCACAGGTGTTGAGCTTCTGAAAGATACACCA GCCCCACGGCTCCTCAAGACACACTTGCCTCTGGCCCTGCTTCCGAAGACCCTGCTGGAT CAGAAAGTCAAGGTGATCTACATCGCCCGCAACGCCAAGGATGTGGCCGTCTCCTATTAC CACTTCTATCGCATGGCCAAGGTGCACCCTGACCCTGGCACCTGGGACAGCTTCCTGGAG AAGTTCATGGCCGGGGAAGTGTGCTACGGGTCCTGGTACCAGCACGTGCAGGAGTGGTGG GAGCTGAGTCACACCCACCCTGTTCTCTACCTCTTCTACGAGGACATAAAGGAGGACCCC AAAAGGGAGATTCAGAAGATCCTGGAGTTTATAGGGCGCTCCCTGCCTGAGGAGACTGTG GATCACATTGTCCAGCGCACATCTTTCAAAGAGATGAAGAAGAACCCCATGACCAACTAC AGCACCATACCCACTGCAGTCATGGACCACAGCATCTCTGCCTTCATGAGGAAAGGCATC ACTGGTGATTGGAAATCCACCTTCACTGTGGCCCAGAATGAGCTCTTTGAAGCCCACTAT GCTAAGAAGATGCGGGCTGCAACTCCGCTTCGCTGGGAGCTGTGA |
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| Protein Properties | |||||
| Number of Residues | 295 | ||||
| Molecular Weight | 34184.0 | ||||
| Theoretical pI | 7.02 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>Sulfotransferase 1A1 MELIQDTSRPPAKYVKGIPLIKYFAEALGPLESFEAWPDDLLISTYPKSGTTWVSEILDL IYQEGDLEKCQRAPVFLRVPFLEFSAPGVPTGVELLKDTPAPRLLKTHLPLALLPKTLLD QKVKVIYIARNAKDVAVSYYHFYRMAKVHPDPGTWDSFLEKFMAGEVCYGSWYQHVQEWW ELSHTHPVLYLFYEDIKEDPKREIQKILEFIGRSLPEETVDHIVQRTSFKEMKKNPMTNY STIPTAVMDHSISAFMRKGITGDWKSTFTVAQNELFEAHYAKKMAGCKLRFRWEL |
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| External Links | |||||
| GenBank ID Protein | AAA85510.1 | ||||
| UniProtKB/Swiss-Prot ID | P50227 | ||||
| UniProtKB/Swiss-Prot Entry Name | ST1A1_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | U35253 | ||||
| GeneCard ID | SULT1A1 | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||