| Identification |
|---|
| BMDB Protein ID
| BMDBP00381 |
| Secondary Accession Numbers
| None |
| Name
| Polypeptide N-acetylgalactosaminyltransferase 6 |
| Synonyms
|
Not Available
|
| Gene Name
| GALNT6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides (By similarity). |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| GALNT6 |
| Gene Sequence
|
>1869 bp
ATGAGGCTGCTCCGCAGACGCCACATGGCCGTGCGCCTGGTCATGGTGGGCAGCGCCTTC
GTGCTCTTTCTCTTCATCCTGCAGAGGGACGTAAGTGGCAGGGAGCAGGCCACAGAGAAG
CCATGGCTGAGGTCCTTGGTGAGCCAGAAGGACCACGTCTTGGACCTCATGCTGGGGGCC
GTGCACAACCTCAGGGACTCGATGCCCAAGTTCCAGATCAGGGCTCCAGAGCCCCAGCAG
ACACTGGCCTCCACCAACCAGTCCTGCCTCCCAGGTTTCTACACCCCAGCTGAGCTGAAG
CCATTCTGGGAACGGCCGCCACAGGACCCCAATGGCCCTGGGGCGGATGGGAAGGCGTTT
CAGAAGAAAGAGTGGACGCCCCAGGAGACCCAGGAAAAGGAAGAGGGCTATAAGAAGCAC
TGCTTCAATGCCTTTGCCAGTGACCGCATCTCCCTGCAGAGGGCCCTGGGGCCGGACACC
CGACCCCCTGAGTGTGTCGACCAGAAGTTCCGGCGCTGCCCCCCGCTGCCTGCCACCAGC
GTCATCATTGTGTTCCACAATGAGGCCTGGTCCACTCTGCTGCGGACGGTGTACAGCGTC
CTGCACACCACCCCTGCCATCCTGCTGAAGGAGATCATTCTGGTAGATGATGCCAGCACG
GACGAGTACTTGAAGGAGCCCCTGGAGCGGTACGTGAAGCAGCTGCAGGTGGTGCAGGTG
GTGCGGCAGCAGGAGAGGAAGGGGCTGATCACCGCCCGGCTGCTGGGGGCCAGCGTGGCC
CAGGCGGAGGTGCTCACCTTCCTGGATGCCCACTGTGAGTGCTTCCACGGCTGGCTAGAG
CCACTCCTGGCTCGCATCGCCGAGGACGAGACGGTGGTGGTGAGCCCAAACATCGTCACC
ATTGACCTGAACACTTTTGAGTTCTCCAAGCCTGTCCAGAGGGGCCGAGTCCAGAGTCGG
GGCAACTTTGACTGGAGCCTGACCTTCGGCTGGGAGGTTTTACCGGCACGAGAGAAGCAG
AGGCGCAAGGATGAGACCTACCCCATCAAATCCCCGACGTTTGCTGGTGGCCTCTTCTCC
ATCTCCAAGTCCTACTTTGAGCACATCGGTACCTATGATAACCAGATGGAGATCTGGGGA
GGGGAGAACGTGGAAATGTCCTTCCGGGTGTGGCAGTGCGGCGGCCAGCTAGAGATTATC
CCCTGCTCTGTGGTCGGACACGTGTTCCGTACCAAGAGCCCCCACACCTTCCCCAAGGGC
ATCAATGTCATTGCTCGCAACCAAGTGCGCCTGGCTGAGGTCTGGATGGATGGCTACAAG
GAGATTTTCTACAGGAGAAATCTGCAGGCAGCACAGATGGCCCGAGAGAAATCCTTTGGC
GACATTTCGGAACGACTGCAGCTGAGGGAGCGACTAAACTGTCACAACTTTTCCTGGTTC
CTGGACAACGTTTACCCGGAGATGTTTGTCCCTGACCTGAAGCCCACCTTCTTTGGAGCT
CTCAAGAACCTCGGCGTGGATCACTGTCTGGATGTGGGAGAGAACAACAACGGGGGAAAG
CCCCTCATCCTGTACACCTGCCATGGCCTCGGTGGCAACCAGTACTTTGAGTACACAACC
CAGAGAGACCTTCGCCACAACATCGCAAAGCAGCTGTGTCTACATGCCAGTGCTGGCACT
CTGGGCCTTAGGAGCTGTCACTTCACCGGCAAGAATAGCCAAGTGCCCAAGGATGAGGAA
TGGGAATTCACCCAGGATCAACTCATCAGGAACTCAGGATCTGGTACCTGCCTGACATCC
AAAGACAAAAAGCCAGTCATGGCCACCTGCAACCCCAGTGATCCCCACCAGCACTGGCTC
TTCATTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 622 |
| Molecular Weight
| 71138.0 |
| Theoretical pI
| 8.07 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Polypeptide N-acetylgalactosaminyltransferase 6
MRLLRRRHMAVRLVMVGSAFVLFLFILQRDVSGREQATEKPWLRSLVSQKDHVLDLMLGA
VHNLRDSMPKFQIRAPEPQQTLASTNQSCLPGFYTPAELKPFWERPPQDPNGPGADGKAF
QKKEWTPQETQEKEEGYKKHCFNAFASDRISLQRALGPDTRPPECVDQKFRRCPPLPATS
VIIVFHNEAWSTLLRTVYSVLHTTPAILLKEIILVDDASTDEYLKEPLERYVKQLQVVQV
VRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDETVVVSPNIVT
IDLNTFEFSKPVQRGRVQSRGNFDWSLTFGWEVLPAREKQRRKDETYPIKSPTFAGGLFS
ISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKG
INVIARNQVRLAEVWMDGYKEIFYRRNLQAAQMAREKSFGDISERLQLRERLNCHNFSWF
LDNVYPEMFVPDLKPTFFGALKNLGVDHCLDVGENNNGGKPLILYTCHGLGGNQYFEYTT
QRDLRHNIAKQLCLHASAGTLGLRSCHFTGKNSQVPKDEEWEFTQDQLIRNSGSGTCLTS
KDKKPVMATCNPSDPHQHWLFI
|
| External Links |
|---|
| GenBank ID Protein
| AAX08745.1 |
| UniProtKB/Swiss-Prot ID
| Q5EA41 |
| UniProtKB/Swiss-Prot Entry Name
| GALT6_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020728 |
| GeneCard ID
| GALNT6 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
