Showing Protein Threonine--tRNA ligase 1, cytoplasmic (BMDBP00386)
| Identification | |||
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| BMDB Protein ID | BMDBP00386 | ||
| Secondary Accession Numbers | None | ||
| Name | Threonine--tRNA ligase 1, cytoplasmic | ||
| Synonyms | Not Available | ||
| Gene Name | TARS1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Translation, ribosomal structure and biogenesis | ||
| Specific Function | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage. | ||
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 20 | ||
| Locus | Not Available | ||
| SNPs | TARS1 | ||
| Gene Sequence |
>2172 bp ATGTCCGAGGAGCAGGCCAGTAGCCCTTCAGCGAAAATGGGAGACGAGGAGAAGCCGGTA GGTGCTGGTGAAGAGAAACAAAAGGAAGGAAGCAAGAAGAAGAATAAAGAAGGATCGGGG GATGGAGGTCGAGCAGAGTTGAATCCTTGGCCCGAATATATTAACACCCGTCTTGAGATG TACAATAAGCTAAAAGCAGAACATGATTCCATTCTGGCAGAAAAGGCAGAAAAAGATAGT AAGCCCATTAAAGTCACCCTGCCTGATGGTAAACAGGTAGATGCAGAATCCTGGAAAACT ACACCATATCAAATTGCTTGTGGAATTAGTCAAGGCCTGGCCGACAACACTGTCATTGCT AAGGTGAATAAAGCCGTCTGGGACCTAGACCGTCCTCTGGAGGAAGATTGCACCTTGGAG CTGCTCAAGTTTGAGGATGAGGAAGCTCAAGCAGTGTATTGGCACTCAAGTGCTCACATA ATGGGTGAAGCCATGGAAAGAGTCTATGGTGGGTGTCTGTGTTATGGACCACCAATAGAA AACGGATTCTATTACGACATGTACCTCGAAGAAGGGGGTGTGTCCAGCAATGATTTCTCT TCTTTGGAGACTTTATGTAAGAAAATCATTAAAGAAAAGCAAGCTTTCGAAAGATTAGAA GTTAAGAAGGAAACTTTACTGGAAATGTTTAAGTACAACAAGTTCAAATGCAGGATTTTG AATGAAAAAGTGAATACTCCAACTACCACAGTCTATAGATGTGGCCCCTTGATAGATCTC TGCCGGGGTCCTCATGTCAGACACACTGGCAAAATCAAGACTTTGAAAATACACAAAAAT TCCTCCACCTACTGGGAAGGCAAGTCAGATATGGAGACTCTACAGAGAATTTACGGCATT TCCTTTCCAGATCCTAAGATGTTGAAAGAATGGGAGAAGTTCCAAGAGGAGGCTAAAAAC CGAGATCATAGGAAAATTGGAAGGGACCAAGAACTCTACTTCTTCCATGAACTCAGCCCT GGGAGTTGCTTTTTCCTGCCCAAGGGAGCCTACATTTATAACACACTTATTGAATTCATC AGGAGTGAATACAGGAAACGAGGATTCCAGGAGGTGGTCACCCCGAACATCTATAATAGC CGGCTCTGGGTGACCTCGGGCCACTGGGAGCACTACAGCGAGAACATGTTCTCCTTTGAA GTGGAAAAGGAGCTGTTTGCTCTGAAACCCATGAACTGCCCGGGACACTGCCTCATGTTT GACCATCGGCCAAGATCCTGGCGAGAGTTGCCTCTGCGAGTTGCTGATTTTGGGGTGCTT CATAGGAATGAGCTGTCAGGAGCACTCACAGGACTTACTCGGGTCCGAAGGTTCCAGCAA GATGATGCGCATATATTCTGTGCCATGGAGCAGATTGAGGATGAAATAAAAGGTTGTTTG GATTTTCTGCGTACAGTATATAGCATATTTGGATTTTCTTTTAAACTGAACCTGTCTACT CGCCCAGAAAAATTCCTTGGAGATATTGAAGTATGGAATCAAGCTGAGAAACAACTTGAA AACAGTCTGAATGACTTTGGTGAAAAGTGGGAATTAAATCCCGGAGATGGAGCTTTCTAT GGTCCAAAGATTGACATCCAGATTAAAGACGCTATTGGGCGGTACCACCAGTGTGCAACA ATACAGTTGGATTTTCAGTTGCCCATTAGATTTAATCTTACTTTTGTAAGCCATGATGGT GATGATAAGAAAAAGCCAGTCATTATCCATAGAGCCATCTTGGGGTCAGTGGAAAGAATG ATTGCTATCCTCACTGAAAACTACGGGGGCAAATGGCCCTTCTGGCTGTCCCCTCGTCAG GTAATGGTAGTTCCAGTGGGACCAACATGTGATGAATATGCCCAAAAGGTACGGCAACAA TTCCACAATGCTAAATTCATGGTGGACATTGATCTGGATCCAGGCTGTACATTAAACAAG AAGATCAGAAATGCACAGTTGGCACAATATAACTTCATCCTAGTTGTTGGTGAAAAAGAG AAAACCAGCGGCACCGTCAATATCCGTACCAGAGACAATAAGGTGCACGGAGAGCGCACC ATCTCGGAAACCATCGAGCGGCTCCAGCAGCTCAAGCACTCCCGCAGCAAACAGGCAGAA GAAGAATTCTAA |
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| Protein Properties | |||
| Number of Residues | 723 | ||
| Molecular Weight | 83492.0 | ||
| Theoretical pI | 6.76 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Threonyl-tRNA synthetase, cytoplasmic MSEEQASSPSAKMGDEEKPVGAGEEKQKEGSKKKNKEGSGDGGRAELNPWPEYINTRLEM YNKLKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIA KVNKAVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIE NGFYYDMYLEEGGVSSNDFSSLETLCKKIIKEKQAFERLEVKKETLLEMFKYNKFKCRIL NEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKTLKIHKNSSTYWEGKSDMETLQRIYGI SFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNTLIEFI RSEYRKRGFQEVVTPNIYNSRLWVTSGHWEHYSENMFSFEVEKELFALKPMNCPGHCLMF DHRPRSWRELPLRVADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCL DFLRTVYSIFGFSFKLNLSTRPEKFLGDIEVWNQAEKQLENSLNDFGEKWELNPGDGAFY GPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTFVSHDGDDKKKPVIIHRAILGSVERM IAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHNAKFMVDIDLDPGCTLNK KIRNAQLAQYNFILVVGEKEKTSGTVNIRTRDNKVHGERTISETIERLQQLKHSRSKQAE EEF |
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| External Links | |||
| GenBank ID Protein | AAI03083.1 | ||
| UniProtKB/Swiss-Prot ID | Q3ZBV8 | ||
| UniProtKB/Swiss-Prot Entry Name | SYTC_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | BC103082 | ||
| GeneCard ID | TARS1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||