Identification
BMDB Protein ID BMDBP00388
Secondary Accession Numbers None
Name Tyrosine 3-monooxygenase
Synonyms Not Available
Gene Name TH
Protein Type Enzyme
Biological Properties
General Function Amino acid transport and metabolism
Specific Function Plays an important role in the physiology of adrenergic neurons.
Pathways
  • Catecholamine biosynthesis
  • Dopamine biosynthesis
  • Dopamine from L-tyrosine: step 1/2
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 29
Locus Not Available
SNPs TH
Gene Sequence
>1476 bp
ATGCCTACCCCCAACGCCGCCTCGCCGCAGGCCAAGGGCTTCCGCAGGGCCGTCTCCGAG
CTGGACGCCAAGCAGGCTGAGGCCATCATGTCCCCACGCTTCGTCGGGAGGCGGCAGAGC
CTCATCCAGGACGCACGCAAGGAGCGGGAGAAGGCGGAGGCCGCGGCCTCATCCTCGGAG
TCCGCGGAGGCGGCAGCCTGGTTGGAGAGGGACGGGGAGGCGGTGCTGACCCTGCTGTTC
GCCCTGCCGCCCACCAGGCCCCCTGCGCTGACCCGGGCTATCAAGGTGTTTGAGACATTC
GAAGCCCACCTCCACCACCTGGAGACCCGACCGGCCCAGCCACTGCGGGCGGGGAGCCCG
CCCCTGGAGTGCTTCGTGCGCTGTGAGGTGCCCGGCCCAGTGGTGCCCGCCCTGCTGAGC
GCCCTGCGCCGCGTGGCAGAAGATGTGCGTGCCGCCGGGGAGAGCAAAGTCCTCTGGTTC
CCAAGGAAAGTGTCCGAGCTGGACAAGTGTCACCACCTCGTCACCAAGTTTGACCCTGAC
CTGGACTTGGATCATCCCGGCTTCTCCGACCAGGCGTACCGCCAGCGCAGGAAGCTGATC
GCCGAGATCGCCTTCCAGTACAAGCAAGGCGACCCCATTCCCCACGTGGAGTACACAGCC
GAGGAGACAGCCACCTGGAAGGAGGTCTACTCCACGCTGCGGGGCCTGTACCCCACCCAC
GCCTGCCGCGAGCACCTGGAGGCCTTCGAGCTGCTGGAGCGCTTCTGCGGGTACCGCGAG
GACCGAATCCCGCAGCTGGAGGACGTCTCACGCTTCCTGAAGGAGAGGACCGGCTTCCAG
CTGCGGCCCGCGGCCGGCCTGCTGTCCGCGCGGGACTTCCTGGCCAGCCTGGCCTTCCGC
GTGTTCCAGTGCACCCAGTACATCCGCCACGCCTCCTCGCCCATGCACTCCCCGGAGCCG
GAGTGCTGCCACGAGCTGCTGGGGCACGTGCCCATGCTCGCCGACCGGACCTTCGCGCAG
TTTTCCCAGGACATCGGGCTCGCATCCTTGGGAGTGTCGGATGAGGAAATTGAGAAGCTG
TCCACGCTGTACTGGTTCACCGTGGAGTTCGGGCTATGCAAACAGAATGGAGAGGTGAAG
GCCTACGGCGCGGGGCTGCTGTCCTCCTACGGGGAGCTCCTGCACTCCCTTTCCGAGGAG
CCTGAGATCCGGGCCTTCGACCCTGATGCAGCGGCCGTGCAGCCCTATCAGGACCAGACC
TACCAGCCCGTCTACTTCGTGTCTGAGAGCTTCAGCGATGCCAAGGACAAGCTCAGGAGC
TACGCCTCCCGCATCCAGCGCCCCTTCTCTGTGAAGTTTGACCCGTACACACTGGCCATC
GACGTGCTGGACAGTCCCCACGCCATCCGGCACGCCCTGGACGGCGTCCAGGACGAGATG
CAGGCCCTGGCCCATGCTCTGAACGCCATCAGCTAG
Protein Properties
Number of Residues 491
Molecular Weight 55123.0
Theoretical pI 5.96
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Tyrosine 3-monooxygenase
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAASSSE
SAEAAAWLERDGEAVLTLLFALPPTRPPALTRAIKVFETFEAHLHHLETRPAQPLRAGSP
PLECFVRCEVPGPVVPALLSALRRVAEDVRAAGESKVLWFPRKVSELDKCHHLVTKFDPD
LDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYSTLRGLYPTH
ACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPAAGLLSARDFLASLAFR
VFQCTQYIRHASSPMHSPEPECCHELLGHVPMLADRTFAQFSQDIGLASLGVSDEEIEKL
STLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQT
YQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRHALDGVQDEM
QALAHALNAIS
GenBank ID Protein AAA30779.1
UniProtKB/Swiss-Prot ID P17289
UniProtKB/Swiss-Prot Entry Name TY3H_BOVIN
PDB IDs
GenBank Gene ID M36794
GeneCard ID TH
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available