| Identification |
|---|
| BMDB Protein ID
| BMDBP00393 |
| Secondary Accession Numbers
| None |
| Name
| Dolichol kinase |
| Synonyms
|
Not Available
|
| Gene Name
| DOLK |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| Not Available |
| SNPs
| DOLK |
| Gene Sequence
|
>1194 bp
ATGACCCGAGAGTGCGCTCCCCCGACCCCTGGGTCCGGGGCGCCGCTGAGTGGGTCCGTG
CTGGCAGAGGCGGCGGTGGTGTTCGTAGTGGTGCTGAGCATCCACGCAGCCGTGTGGGAT
CGATACTCGTGGTGCGCCGTGGCCCTCGCGGTGCAGGCCTTCTACGTTCAGTACAAATGG
GACCGGCTCCTACAGCAGGGAAGCGCGGTCTTCCAGTTCCGAATGTCCGCGAACAGCGGC
CTACTGCCCGCTTCGGTGGTCATGCCTTTGCTAGGACTTGTTATGAAGGAGCGCTGCCAG
GCTGCGGGGAACCCATATTTCGAGCGGTTTGGAATTGTGGTGGCGGCCACGGGCATGGCA
GTGGCCCTCTTCTCCTCAGTATTGGCCCTGGGCATCACTCGCCCGGTGCCCACCAACACC
TGTGTCATCTCGGGCTTGGCTGGAGGCGTCATCATTTACATCATGAAGCACTCGCTGAGT
GTCGGCGAGGTGATCGAGGTCCTGGAGGCCCTGCTGATCTTCGTGTACCTCAACATGATC
CTGCTGTACCTGCTGCCTCGCTGCTTCACCCCCGGAGAGGCGCTGCTGGTCCTGGGTGGC
ATCAGCTTCATGCTCAACCAGCTCATCAAGCGCTCTCTCACTGTGGTGGAAAGCCAGGGG
GACCCCTTGGACTTCTTCCTGCTCGTGGTGGTGGTAGGCATGGTGCTCATGGGCATCTTC
TTCAGCACCCTCTTTGTATTCATGGACTCGGGCACCTGGGCCTCTTCCATCTTCTTCCAC
CTCATGACCTGCGTCCTGGGCCTTGGCGTCGTCCTGCCCTGGCTGCACCGCCTCATCCGC
AGGAACCCCCTGCTGTGGCTTTTTCAATTCCTCTTCCAGACAGAGACCCGAGTCTACCTC
CTAGCTTATTGGTGTCTGCTGGCCACCGTGGCCTGCCTGGTGGTTCTGTACCAGAATGCC
AAGCGGTCATCTTCTGAGTCCAAGAAAGCACCAGGCCCCCACCATCACTCGAAAGTATTT
CCACTTCATTGTGGTAGCCACCTACATCCCAGGTATCATTTTGGACCGGCCCCTGCTCTA
CGTGGCCGCCACCGTATGTCTGGCTGTCTTCATCTTCCTGGAGTATGTGCGCTACTTCCG
CATCAAGCCCCTGGGCCATACCCTGCGAAGCCTTCTGTCCCTCTTCCTGGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 538 |
| Molecular Weight
| 59190.0 |
| Theoretical pI
| 8.63 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 19-39
- 75-95
- 112-132
- 135-155
- 164-184
- 189-209
- 225-245
- 255-275
- 298-318
- 338-354
- 360-380
- 402-422
- 437-457
- 473-493
- 496-516
|
| Protein Sequence
|
>Dolichol kinase
MTRECAPPTPGSGAPLSGSVLAEAAVVFVVVLSIHAAVWDRYSWCAVALAVQAFYVQYKW
DRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMA
VALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEALLIFVYLNMI
LLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIF
FSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYL
LAYWCLLATVACLVVLYQNAKRSSSESKKHQAPTITRKYFHFIVVATYIPGIILDRPLLY
VAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIW
LVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSI
FAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA
|
| External Links |
|---|
| GenBank ID Protein
| AAX46357.1 |
| UniProtKB/Swiss-Prot ID
| Q58CR4 |
| UniProtKB/Swiss-Prot Entry Name
| DOLK_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021510 |
| GeneCard ID
| DOLK |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
