Showing Protein Protein-L-isoaspartate(D-aspartate) O-methyltransferase (BMDBP00397)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00397 |
| Secondary Accession Numbers | None |
| Name | Protein-L-isoaspartate(D-aspartate) O-methyltransferase |
| Synonyms | Not Available |
| Gene Name | PCMT1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Posttranslational modification, protein turnover, chaperones |
| Specific Function | Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 9 |
| Locus | Not Available |
| SNPs | PCMT1 |
| Gene Sequence |
>684 bp ATGGCCTGGAAATCCGGCGGCGCCAGCCACTCGGAGCTAATCCACAACCTCCGCAAAAAT GGAATCATCAAGACAGATAAAGTGTTTGAAGTAATGTTGGCCACAGACCGCTCCCACTAT GCAAAATGTAACCCTTATATGGATTCTCCACAATCAATAGGGTTCCAAGCAACAATCAGT GCTCCACACATGCATGCATATGCACTAGAACTTCTATTTGATCAGTTGAATGAAGGAGCT AAAGCTCTTGATGTAGGATCTGGAAGTGGAATCCTTACTGCATGTTTTGCACGTATGGTT GGACCTAGTGGGAAAGTCATAGGAATTGACCACATTAAAGAGCTAGTAGATGACTCAATA AATAATGTCAGAAAGGATGATCCAATGCTTTTGTCTACAGGGAGGGTGCAACTGGTTGTG GGGGATGGACGAATGGGATATGCCGCAGAAGCCCCTTATGATGCTATTCACGTAGGAGCT GCAGCCCCAGTTGTGCCCCAGGCACTAATAGACCAGTTAAAGCCTGGTGGAAGATTGATA TTGCCAGTTGGTCCTGCAGGTGGAAACCAGATGTTGGAGCAGTATGACAAGCTGCAAGAT GGCAGTGTCAAAATGAAACCTCTGATGGGAGTGATATACGTGCCTTTAACAGATAAAGAA AAGCAGTGGTCCAGGTGGAAGTGA |
| Protein Properties | |
| Number of Residues | 227 |
| Molecular Weight | 24565.0 |
| Theoretical pI | 7.69 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Protein-L-isoaspartate(D-aspartate) O-methyltransferase MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNPYMDSPQSIGFQATIS APHMHAYALELLFDQLNEGAKALDVGSGSGILTACFARMVGPSGKVIGIDHIKELVDDSI NNVRKDDPMLLSSGRVQLVVGDGRMGYAAEAPYDAIHVGAAAPVVPQALIDQLKPGGRLI LPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKEKQWSRWK |
| External Links | |
| GenBank ID Protein | AAI09664.1 |
| UniProtKB/Swiss-Prot ID | P15246 |
| UniProtKB/Swiss-Prot Entry Name | PIMT_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC109663 |
| GeneCard ID | PCMT1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |