Showing Protein tRNA (guanine(37)-N1)-methyltransferase (BMDBP00404)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00404 |
| Secondary Accession Numbers | None |
| Name | tRNA (guanine(37)-N1)-methyltransferase |
| Synonyms | Not Available |
| Gene Name | TRMT5 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in tRNA (guanine-N1-)-methyltransferase activity |
| Specific Function | Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 10 |
| Locus | Not Available |
| SNPs | TRMT5 |
| Gene Sequence |
>1494 bp ATGAGGAGCTTATTGAAACAATTTGCATTCTCAAGAAGACTTCTCAAAGTGGAAAGCTGT AGAATAACTGAGTCAGCATCACTGATTCTACTACCTTGGGCATCGTTGATACAGAAGCTT AACAGAGTACCTGTTATTTTCTTGCTGGATCAAAGAAAAAGATTCTCAACCATGCCTGAA ATAGAAACAAATCACAGAGACTCTGAATTGTTTTCCCCACCCTCTGAAGTTCGAGGAATG ACAGAACTTGATAGAACAGCTTTTAAAAAGACAGTCACCATCCCAGTGCTTAAAGTGAGG AAAGAAGTAGTCAATAAACTGATGCGATCCCTTAAAAGAGCAGCACTGCAGCGCCCAGGC ATAAAACGTGTGATTGAAGATCCAGAAGATGGAGAAGGTAGACTAATTATGTTGGATCCC TATAAAATGTTTACTGTTGACTCCTTTGAGAAAGAAGAACTCAGTATTTTAAAGCAGCTG AATGTCAATCCACAGATATCGAAATATAATTTGGACCTAACTTATGAAAACTTTAAGTCA GAAGAAATCTTGAGAGCTGTGCTTCCTGAAGGTCAAGATGTGACCTCAGGGTTTAGCAGA GTTGGACACATTGCTCACCTGAACCTTCGAGATCATCAACTACCTTACAAGCATTTAATT GGCCAAGTTATGATTGACAAAAATCCAGGAATCACCTCAGCAGTAAATAAAATCAATAAT ATTGATAATACCTACCGAAATTTTGAAATGGAAGTACTATCTGGAGAGGAGAATATGATG ACAAAGGTTCGAGAAAACAATTACACCTATGAATTTGATTTTTCAAAAGTCTACTGGAAT CCTCGTCTCTCCACAGAACACAGCCGTATCACAGAACTTCTCAAACCTGGGGATGTCCTA TTTGATGTCTTTGCTGGGGTTGGGCCCTTTGCCATTCCAGCAGCAAAGAAAAAGTGCACT GTGTTTGCTAATGATCTCAATCCTGAATCCCATAAATGGCTACTGCACAATTGTAAATTA AATAAAGTGGACCAAAAGGTAAAAGTCTTTAACTTGGATGGGAGAGACTTCCTGCAAGGA CCAGTCAGAGAAGAGTTAATGCAGCAGCTAGGACCACTGTCTAAAGAAAGAAAACACTCT GTGCACATTGTCATGAATTTGCCAGCAAAGGCTATTGAGTTTCTCAGTGCTTTCAAAGCA CTCTTAGAGGGACAGCCATGTGGCAGTGAACTCCTTCCCATTGTGCACTGTTACAGCTTT TCCAAAGATGCTAATCCAGCTAAGGATGTTCAGCAACGAGCTGCAACTGTGTTAGGCATC TCCTTGGAGGCATATAGTTCAGTTCACCTAGTAAGAAATGTGGCCCCTAACAAGGAAATG TTATGCATCACTTTTCGGATTCCTGCTGCTATACTTTACAAGAACCAGACCGTGAATCGA GACAATCATGAAGGTCCACCTCTTAAACGCCAGAGGACAGATAAAGACTTCTAA |
| Protein Properties | |
| Number of Residues | 497 |
| Molecular Weight | 56954.0 |
| Theoretical pI | 9.64 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>tRNA (guanine-N(1)-)-methyltransferase MRSLLKQFAFSRRLLKVESCRITESASLILLPWASLIQKLNRVPVIFLLDQRKRFSTMPE IETNHRDSELFSPPSEVRGMTELDRTAFKKTVTIPVLKVRKEVVNKLMRSLKRAALQRPG IKRVIEDPEDGEGRLIMLDPYKMFTVDSFEKEELSILKQLNVNPQISKYNLDLTYENFKS EEILRAVLPEGQDVTSGFSRVGHIAHLNLRDHQLPYKHLIGQVMIDKNPGITSAVNKINN IDNTYRNFEMEVLSGEENMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGDVL FDVFAGVGPFAIPAAKKKCTVFANDLNPESHKWLLHNCKLNKVDQKVKVFNLDGRDFLQG PVREELMQQLGPLSKERKHSVHIVMNLPAKAIEFLSAFKALLEGQPCGSELLPIVHCYSF SKDANPAKDVQQRAATVLGISLEAYSSVHLVRNVAPNKEMLCITFRIPAAILYKNQTVNR DNHEGPPLKRQRTDKDF |
| External Links | |
| GenBank ID Protein | AAI05168.1 |
| UniProtKB/Swiss-Prot ID | Q3MHN8 |
| UniProtKB/Swiss-Prot Entry Name | TRM5_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC105167 |
| GeneCard ID | TRMT5 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |