Showing Protein Hyaluronidase-2 (BMDBP00424)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00424 |
| Secondary Accession Numbers | None |
| Name | Hyaluronidase-2 |
| Synonyms | Not Available |
| Gene Name | HYAL2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in hyalurononglucosaminidase activity |
| Specific Function | Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 22 |
| Locus | Not Available |
| SNPs | HYAL2 |
| Gene Sequence |
>1422 bp ATGTGGACAGGCCTGGGCCCCGCCGTCACACTGGCCCTGGTGTTGGTGGTGGCATGGGCC ACGGAGCTGAAGCCCACAGCACCACCCATCTTCACGGGCCGGCCCTTTGTGGTCGCATGG GATGTGCCCACACAGGACTGTGGCCCGCGCCACAAGATGCCATTGGACCCAAAGGACATG AAGGCCTTTGATGTTCAGGCTTCACCTAACGAGGGTTTTGTAAATCAGAACATCACCATC TTCTACCGTGACCGGCTGGGCATGTATCCACACTTCAATTCGGTGGGGAGGTCAGTACAT GGTGGTGTGCCACAGAATGGCAGCCTCTGGGTACACCTGGAGATGCTGAAGGGACACGTG GAACACTACATTCGTACACAGGAGCCTGCAGGGCTGGCAGTCATCGACTGGGAGGACTGG CGGCCAGTGTGGGTGCGCAACTGGCAGGACAAGGATGTGTACCGCCGATTATCACGCCAT TTGGTAGCCATTCGCCACCCTGATTGGCCACCAGAGCGCGTAGCCAAGGAGGCGCAGTAT GAGTTTGAGTTCGCTGCACGGCAGTTCATGCTGGAGACATTGCGATTTGTCAAGGCGTTT CGGCCTCGGCACCTATGGGGCTTCTACCTCTTCCCTGACTGTTACAACCATGATTATGTG CAGAACTGGGAGACCTATACAGGCCGCTGCCCTGATGTTGAGGTCTCCCGAAATGACCAG CTGGCCTGGCTCTGGGCCGAGAGCACGGCCCTCTTCCCCTCTGTCTACTTGGAAGAGACA CTGGCTTCCTCCACTCACGGCCGCAACTTTGTCAGCTTTCGTGTCCAGGAGGCTCTTCGC GTGGCTGACGTCCACCATGCCAACCATGCACTCCCCGTCTACGTCTTCACGAGGCCCACC TATAGCCGTGGACTCACAGGGCTTAGCGAGATGGATCTCATCTCCACCATTGGTGAGAGT GCTGCCCTGGGTGCAGCTGGCGTCATCCTCTGGGGTGACGCAGGGTTTACCACCAGCAAC GAGACCTGCCGACGCCTCAAGGATTATCTGACTCGGTCATTGGTACCCTATGTCGTCAAT GTGTCCTGGGCTGCCCAGTACTGCAGCTGGGCCCAGTGCCATGGCCATGGGCGCTGTGTG CGCCGGGACCCCAACGCTCACACCTTCCTGCACCTCAGTGCCAGCAGCTTCCGTCTAGTG CCTAGCCACGCACCTGATGAGCCGCGGCTGCGACCAGAGGGGGAACTCAGTTGGGCCGAC CGCAACCACCTACAGATGCACTTTCGCTGCCAGTGCTACTTAGGCTGGGGCGGTGAGCAA TGCCAGTGGGACCGCAGGCGGGCAGCTGGGGGTGCCAGTGGGGCCTGGGCTGGGTCCCAC CTCACTGGCCTGCTGGCAGTGGCAGTCCTGGCCTTCACCTAG |
| Protein Properties | |
| Number of Residues | 473 |
| Molecular Weight | 53881.0 |
| Theoretical pI | 7.66 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Hyaluronidase-2 MWTGLGPAVTLALVLVVAWATELKPTAPPIFTGRPFVVAWDVPTQDCGPRHKMPLDPKDM KAFDVQASPNEGFVNQNITIFYRDRLGMYPHFNSVGRSVHGGVPQNGSLWVHLEMLKGHV EHYIRTQEPAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRHLVAIRHPDWPPERVAKEAQY EFEFAARQFMLETLRFVKAFRPRHLWGFYLFPDCYNHDYVQNWETYTGRCPDVEVSRNDQ LAWLWAESTALFPSVYLEETLASSTHGRNFVSFRVQEALRVADVHHANHALPVYVFTRPT YSRGLTGLSEMDLISTIGESAALGAAGVILWGDAGFTTSNETCRRLKDYLTRSLVPYVVN VSWAAQYCSWAQCHGHGRCVRRDPNAHTFLHLSASSFRLVPSHAPDEPRLRPEGELSWAD RNHLQMHFRCQCYLGWGGEQCQWDRRRAAGGASGAWAGSHLTGLLAVAVLAFT |
| External Links | |
| GenBank ID Protein | AAL78385.1 |
| UniProtKB/Swiss-Prot ID | Q8SQG8 |
| UniProtKB/Swiss-Prot Entry Name | HYAL2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF411973 |
| GeneCard ID | HYAL2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |