| Identification |
|---|
| BMDB Protein ID
| BMDBP00431 |
| Secondary Accession Numbers
| None |
| Name
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta |
| Synonyms
|
Not Available
|
| Gene Name
| PDE6B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 3',5'-cyclic-GMP phosphodiesterase activity |
| Specific Function
| This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| PDE6B |
| Gene Sequence
|
>2562 bp
ATGAGCCTCAGTGAGGGGCAGGTGCACAGGTTCCTGGACCAGAACCCCGGCTTCGCGGAC
CAGTACTTTGGGAGGAAGCTGAGCCCGGAGGATGTGGCCAATGCCTGCGAGGACGGGTGC
CCCGAGGGCTGCACCAGCTTCCGAGAGCTGTGCCAGGTGGAGGAGAGCGCGGCCCTGTTC
GAGCTGGTGCAGGACATGCAGGAGAACGTGAACATGGAGCGCGTGGTCTTCAAGATCCTG
CGGCGCCTCTGCTCCATCCTGCACGCCGACCGCTGCAGCCTCTTCATGTACCGCCAGCGC
AATGGTGTGGCCGAGCTCGCCACCCGCCTCTTCAGCGTGCAGCCCGACAGCGTCCTGGAG
GACTGCCTGGTGCCTCCTGACTCTGAGATCGTCTTCCCGCTGGACATCGGGGTCGTGGGC
CACGTGGCTCAGACCAAGAAGATGGTGAATGTCCAGGACGTGATGGAGTGCCCCCACTTC
AGCTCCTTCGCGGATGAGCTGACCGACTATGTGACGAGGAACATCCTGGCCACACCCATC
ATGAACGGCAAAGATGTCGTGGCTGTGATCATGGCTGTGAACAAGCTGGATGGCCCATGT
TTCACAAGTGAAGATGAAGACGTTTTCCTGAAATACCTGAACTTCGGGACATTAAACCTG
AAGATCTACCACTTGAGCTACCTGCACAACTGCGAGACTCGCCGTGGCCAGGTGCTGCTG
TGGTCGGCCAACAAGGTGTTTGAGGAGCTGACAGACATCGAGAGGCAGTTTCACAAGGCC
TTCTACACTGTACGGGCCTATCTGAACTGTGACCGGTACTCGGTGGGCCTCCTGGACATG
ACCAAGGAGAAGGAATTCTTTGATGTGTGGCCCGTGCTGATGGGAGAGGCCCAGGCGTAC
TCGGGCCCCCGCACACCTGACGGCCGAGAAATCCTCTTCTACAAAGTCATAGACTACATC
CTCCACGGCAAGGAAGACATCAAGGTCATCCCCTCACCCCCGGCTGACCACTGGGCCCTT
GCCAGCGGCCTTCCAACCTACGTGGCAGAAAGCGGTTTTATCTGTAATATTATGAATGCC
CCTGCCGACGAAATGTTCAATTTTCAGGAGGGGCCTCTGGACGACTCTGGGTGGATCGTC
AAGAACGTCCTCTCCATGCCCATCGTCAACAAGAAGGAGGAGATCGTGGGGGTCGCGACA
TTTTACAACAGGAAGGACGGGAAGCCCTTCGATGAGCAGGATGAAGTCCTGATGGAGTCT
CTCACACAGTTCCTGGGCTGGTCGGTGCTGAACACTGACACCTACGACAAGATGAACAAG
CTGGAGAACCGCAAGGACATCGCCCAAGACATGGTCCTGTACCACGTGAGATGTGACAGA
GAGGAAATCCAGCTGATCCTGCCAACCAGAGAACGCCTCGGGAAGGAGCCTGCCGACTGC
GAGGAGGACGAGCTGGGGAAAATCCTGAAGGAAGTGCTGCCCGGGCCCGCCAAGTTCGAC
ATCTATGAGTTCCACTTCTCGGACCTGGAGTGCACGGAACTGGAGCTGGTCAAATGCGGT
ATCCAGATGTACTATGAGCTGGGTGTGGTTCGAAAGTTCCAGATCCCCCAGGAGGTCCTG
GTGCGGTTCCTGTTCTCCGTGAGCAAGGGCTACAGGAGAATCACCTACCACAACTGGCGC
CACGGCTTCAACGTGGCCCAGACCATGTTCACGCTGCTCATGACAGGCAAGCTGAAGAGC
TACTACACGGACCTGGAGGCCTTTGCCATGGTGACCGCCGGCCTGTGCCATGACATTGAC
CATCGGGGCACCAACAACCTCTACCAGATGAAGTCCCAGAACCCTTTAGCCAAGCTCCAC
GGCTCCTCGATTTTGGAGCGACACCACCTGGAGTTCGGGAAGTTCCTGCTCTCCGAGGAG
ACCCTGAACATCTACCAGAACCTGAACCGGCGGCAGCACGAGCACGTGATCCACCTCATG
GACATCGCCATCATCGCCACAGACCTGGCGCTCTACTTTAAAAAAAGGACAATGTTCCAG
AAGATTGTGGATGAGTCCAAGAACTACGAGGACAGGAAGAGCTGGGTGGAGTACCTGTCC
TTGGAGACCACGAGGAAGGAGATCGTCATGGCCATGATGATGACGGCATGTGACCTGTCT
GCCATCACCAAGCCCTGGGAAGTCCAGAGCAAGGTTGCTCTGCTGGTGGCAGCTGAGTTC
TGGGAGCAAGGGGACTTGGAGAGGACGGTTCTGGATCAGCAGCCCATCCCAATGATGGAC
CGGAACAAGGCAGCTGAGCTCCCCAAGCTACAGGTCGGCTTCATCGACTTCGTGTGCACG
TTTGTGTACAAGGAGTTCTCCCGCTTCCACGAGGAGATCCTGCCCATGTTTGACCGGCTG
CAGAACAACAGGAAGGAGTGGAAGGCCTTGGCCGATGAGTACGAAGCCAAGGTGAAGGCC
CTGGAGGAGGACCAGAAGAAAGAGACGACGGCCAAGAAAGTGGGCACAGAAATCTGCAAC
GGCGGCCCGGCACCCCGGTCTTCTACCTGCCGCATCCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 853 |
| Molecular Weight
| 98331.0 |
| Theoretical pI
| 5.03 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
MSLSEGQVHRFLDQNPGFADQYFGRKLSPEDVANACEDGCPEGCTSFRELCQVEESAALF
ELVQDMQENVNMERVVFKILRRLCSILHADRCSLFMYRQRNGVAELATRLFSVQPDSVLE
DCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVMECPHFSSFADELTDYVTRNILATPI
MNGKDVVAVIMAVNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQAY
SGPRTPDGREILFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNA
PADEMFNFQEGPLDDSGWIVKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMES
LTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDREEIQLILPTRERLGKEPADC
EEDELGKILKEVLPGPAKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVL
VRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDID
HRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLM
DIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLS
AITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCT
FVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKVKALEEDQKKETTAKKVGTEICN
GGPAPRSSTCRIL
|
| External Links |
|---|
| GenBank ID Protein
| AAA30440.1 |
| UniProtKB/Swiss-Prot ID
| P23439 |
| UniProtKB/Swiss-Prot Entry Name
| PDE6B_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| J05553 |
| GeneCard ID
| PDE6B |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
