Showing Protein Alpha-1-antiproteinase (BMDBP00438)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00438 |
| Secondary Accession Numbers | None |
| Name | Alpha-1-antiproteinase |
| Synonyms | Not Available |
| Gene Name | SERPINA1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in serine-type endopeptidase inhibitor activity |
| Specific Function | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Inhibits trypsin, chymotrypsin and plasminogen activator (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 21 |
| Locus | Not Available |
| SNPs | SERPINA1 |
| Gene Sequence |
>1251 bp ATGGCACTCTCCATCACGCGGGGCCTTCTGCTGCTGGCAGCCCTGTGCTGCCTGGCCCCC ATCTCCCTGGCTGGAGTTCTCCAAGGACACGCTGTCCAAGAGACAGATGATACATCCCAC CAGGAAGCAGCGTGCCACAAGATTGCCCCCAACCTGGCCAACTTTGCCTTCAGCATATAC CACCATTTGGCTCATCAGTCCAACACCAGCAACATCTTCTTCTCCCCCGTGAGCATCGCT TCAGCCTTTGCGATGCTCTCCCTGGGAGCCAAGGGCAACACTCACACTGAGATCCTGAAG GGCCTGGGTTTCAACCTCACTGAGCTCGCAGAGGCTGAGATCCACAAAGGCTTTCAGCAT CTTCTCCACACCCTGAACCAGCCAAACCACCAGCTGCAACTGACCACTGGCAATGGTCTG TTCATCAATGAGAGTGCAAAGCTAGTGGATACGTTTTTGGAGGATGTCAAGAACCTGTAT CACTCCGAAGCCTTCTCCATCAACTTCAGGGATGCTGAGGAGGCCAAGAAGAAGATCAAC GATTATGTAGAGAAGGGAAGCCATGGAAAAATTGTGGAGTTGGTAAAGGTTCTTGACCCA AACACAGTTTTTGCTCTGGTGAATTACATTTCCTTTAAAGGAAAATGGGAGAAGCCCTTC GAGATGAAGCACACCACAGAGAGGGACTTCCATGTGGACGAGCAAACCACTGTGAAGGTG CCCATGATGAACCGCCTGGGCATGTTTGACCTCCACTACTGCGACAAGCTCGCCAGCTGG GTGCTGCTGTTGGACTACGTGGGCAACGTCACCGCCTGCTTCATCCTGCCCGACCTGGGG AAACTGCAGCAGCTGGAGGACAAGCTCAACAACGAACTCCTCGCCAAGTTCCTGGAAAAG AAATATGCAAGTTCTGCCAATTTACATTTGCCCAAACTGTCCATTTCTGAAACGTACGAT CTAAAAAGTGTCCTGGGCGATGTGGGCATCACCGAGGTCTTCAGCGATAGGGCTGACCTC TCAGGGATCACCAAGGAACAGCCTCTGAAGGTGTCCAAGGCTCTCCACAAGGCTGCACTG ACCATCGATGAGAAAGGGACAGAAGCTGTCGGGTCCACGTTTCTGGAAGCCATCCCCATG TCCCTTCCCCCAGACGTCGAGTTCAACAGACCCTTCCTCTGCATCCTCTACGACAGAAAC ACCAAATCTCCCCTCTTCGTGGGAAAGGTGGTGAATCCCACCCAAGCCTAA |
| Protein Properties | |
| Number of Residues | 416 |
| Molecular Weight | 46104.0 |
| Theoretical pI | 6.51 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Alpha-1-antiproteinase MALSITRGLLLLAALCCLAPISLAGVLQGHAVQETDDTSHQEAACHKIAPNLANFAFSIY HHLAHQSNTSNIFFSPVSIASAFAMLSLGAKGNTHTEILKGLGFNLTELAEAEIHKGFQH LLHTLNQPNHQLQLTTGNGLFINESAKLVDTFLEDVKNLYHSEAFSINFRDAEEAKKKIN DYVEKGSHGKIVELVKVLDPNTVFALVNYISFKGKWEKPFEMKHTTERDFHVDEQTTVKV PMMNRLGMFDLHYCDKLASWVLLLDYVGNVTACFILPDLGKLQQLEDKLNNELLAKFLEK KYASSANLHLPKLSISETYDLKSVLGDVGITEVFSDRADLSGITKEQPLKVSKALHKAAL TIDEKGTEAVGSTFLEAIPMSLPPDVEFNRPFLCILYDRNTKSPLFVGKVVNPTQA |
| External Links | |
| GenBank ID Protein | CAA44840.1 |
| UniProtKB/Swiss-Prot ID | P34955 |
| UniProtKB/Swiss-Prot Entry Name | A1AT_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | X63129 |
| GeneCard ID | SERPINA1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |