Identification
BMDB Protein ID BMDBP00439
Secondary Accession Numbers None
Name Xylosyltransferase 2
Synonyms Not Available
Gene Name XYLT2
Protein Type Enzyme
Biological Properties
General Function Involved in acetylglucosaminyltransferase activity
Specific Function Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
Pathways
  • Chondroitin sulfate biosynthesis
  • Glycan metabolism
  • Heparan sulfate biosynthesis
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 19
Locus Not Available
SNPs XYLT2
Gene Sequence Not Available
Protein Properties
Number of Residues 867
Molecular Weight 97189.0
Theoretical pI 8.69
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 16-36
Protein Sequence
>Xylosyltransferase 2
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSVLEDDEPGEKGRQKKSRPLDPSEG
SKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRHRTGRRIPPTPPPEAPGR
QNLSGAAAEEALVGAAGFPHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASSKQC
QQEIANVVCLHQAGSLMPKAVPRHCQRAGKMSPGIPWDEVRAQQPADGPPVRIAYMLVVH
GRAIRQLKRLLKAVYHKQHFFYVHVDERSNYLHREVVELARQYDNVRVTPWRMVTIWGGA
SLLRMYLRSMQDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDN
SRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLVA
QLRQFYTYTLLPAESFFHTVLEISPACESLVDNNMRVTTWNRKMGSKSQYKHIVDWCGCS
PNDFKPQDFLRLQQTARPTFFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVY
DEPDGIHSLSDVTLTLYHSFSRLGLRRAEASLRAPGESSCRFEPRGLPSSVHLYFYDDHF
QGYLVTQAVQSSAQGPAETLEMWLMPQGSLKLLGHSDQASRLQSLEVGQVGTEWDPKERL
FRNFGGLLGPLDEPVAMQRWARGPNLTVTVVWIDPTYVVATSYDIVVDAETEVTQYKPPL
SRPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKGKFSQMIAGPPHNEYMEQSF
QGLSGILNLPQLEPAEEAARLHAELTGPALEAWTDGEQSSFWSVAGVCAVGPSACPSLEL
CRLTSWSSLSPDPKSELGPVKADGRLR
GenBank ID Protein CAI29053.1
UniProtKB/Swiss-Prot ID Q5QQ49
UniProtKB/Swiss-Prot Entry Name XYLT2_BOVIN
PDB IDs Not Available
GenBank Gene ID AJ866726
GeneCard ID XYLT2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available