Showing Protein Adenylate cyclase type 1 (BMDBP00442)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00442 | ||
| Secondary Accession Numbers | None | ||
| Name | Adenylate cyclase type 1 | ||
| Synonyms | Not Available | ||
| Gene Name | ADCY1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Signal transduction mechanisms | ||
| Specific Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:2472670, PubMed:2022671. PubMed:19029295). Mediates responses to increased cellular Ca(2+)/calmodulin levels (PubMed:2022671, PubMed:19029295). May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity). | ||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 4 | ||
| Locus | Not Available | ||
| SNPs | ADCY1 | ||
| Gene Sequence |
>3405 bp ATGGCGGGGGCGCCGCGCGGCCGAGGCGGCGGCGGAGGCGGAGGCGGCGCGGGCGAGTCT GGGGGCGCCGAGCGGGCGGCGGGGCCGGGCGGCCGGCGCGGGCTGCGGGCGTGCGATGAG GAGTTCGCGTGCCCCGAGCTGGAGGCGCTGTTCCGCGGCTACACGCTGCGGCTGGAGCAG GCGGCGACGCTGAAGGCGCTGGCCGTGCTCAGCCTGCTGGCGGGCGCGCTGGCCCTGGCC GAGCTGCTGGGCGCGCCGGGGCCCGCGCCCGGCCTGGCTAAGGGCTCGCACCCCGTGCAC TGCGTGCTCTTCCTGGCGCTGCTCGTGGTCACCAACGTCCGCTCGCTGCAGGTGCCCCAG CTGCAGCAGGTCGGCCAGCTCGCGCTGCTCTTCAGCCTCACCTTCGCTCTGCTGTGCTGT CCCTTCGCGCTCGGCGGCCCCGCCGGTGCCCACGCCGGGGCGGCAGCGGTGCCGGCGACA GCCGATCAGGGAGTCTGGCAGCTCCTTTTGGTCACCTTCGTGTCCTATGCCCTGCTGCCC GTGCGCAGCCTGCTGGCCATCGGCTTCGGGCTCGTGGTGGCCGCCTCGCACTTGCTGGTC ACGGCTACGTTGGTCCCCGCCAAGCGCCCACGTCTCTGGAGAACGCTGGGTGCCAACGCT CTGCTCTTCCTCGGTGTGAACGTGTATGGCATCTTCGTGAGGATCCTGGCTGAGCGCGCC CAGAGGAAGGCCTTCCTGCAGGCCCGGAACTGCATTGAGGACCGGCTGAGGCTGGAGGAT GAGAATGAGAAGCAGGAGCGGCTGCTCATGAGCCTCCTGCCTCGGAATGTTGCCATGGAG ATGAAGGAGGACTTCCTGAAGCCCCCTGAGAGGATTTTCCACAAGATTTACATCCAGCGG CATGACAACGTGAGCATCCTCTTTGCAGACATCGTGGGCTTCACAGGCTTGGCGTCACAG TGCACGGCCCAGGAGCTGGTGAAACTCCTCAATGAGCTCTTCGGGAAGTTTGACGAGCTG GCCACAGAGAACCACTGCCGCCGCATCAAGATCCTGGGAGATTGCTACTACTGCGTGTCT GGCCTCACTCAGCCCAAGACTGACCACGCCCACTGCTGTGTGGAGATGGGCCTGGACATG ATCGACACCATCACGTCCGTGGCTGAGGCCACTGAGGTGGACTTGAACATGCGTGTGGGG CTGCACACCGGCAGGGTCCTCTGCGGGGTCCTGGGCCTGCGTAAGTGGCAGTATGATGTG TGGTCCAACGACGTGACCCTGGCCAACGTCATGGAGGCTGCCGGCCTGCCTGGGAAGGTT CACATCACAAAGACCACCCTGGCGTGCCTGAATGGTGACTATGAGGTGGAGCCGGGACAC GGACACGAGAGGAACAGTTTTCTGAAAACTCATAACATTGAGACCTTTTTTATTGTGCCC TCGCATCGGCGAAAGATATTTCCAGGGCTGATTCTCTCAGACATAAAACCGGCCAAGAGG ATGAAGTTCAAGACCGTGTGCTACCTGCTGGTGCAGCTCATGCACTGCCGGAAGATGTTC AAGGCCGAGATCCCTTTCTCCAACGTCATGACCTGTGAGGATGACGACAAGCGGAGGGCA CTGAGAACAGCCTCGGAAAAACTCAGAAACCGCTCGTCTTTCTCTACAAACGTTGTCCAA ACCACCCCCGGCACACGTGTCAACAGGTACATCGGCCGCCTCCTGGAAGCCCGCCAGATG GAGCTGGAGATGGCAGACCTGAACTTCTTCACCCTGAAGTACAAGCAAGCTGAGCGAGAG CGAAAGTACCACCAGCTTCAGGACGAGTATTTCACCAGCGCCGTGGTTCTGGCTCTCATT CTGGCCGCCTTATTCGGCCTTGTCTACCTTCTAATAATCCCACAGAGTGTGGCTGTCCTG CTCCTGCTGGTGTTCTGCATCTGCTTCCTGGTGGCCTGTGTCCTGTACCTACACATCACC CGGGTCCAGTGTTTTCCAGGGTGCCTGACCATCCAGATCCGCACCGTCTTGTGCATCTTC ATCGTGGTCTTAATCTACTCTGTGGCCCAAGGCTGTGTGGTGGGCTGCCTGCCTTGGTCC TGGAGCTCCAGTCCCAACGGGTCCCTGGTGGTCCTGTCTTCTGGGGGCCGGGACCCAGTG CTGCCTGTCCCGCCCTGCGAGTCTGCGCCCCATGCCCTGCTGTGCGGCCTCGTGGGCACC CTCCCGCTGGCCATATTCCTGCGGGTCTCCTCCTTGCCAAAAATGATCCTGCTCGCCGTG CTCACCACCTCCTACATCCTCGTCCTGGAGCTCAGCGGGTACACGAAGGCCATGGGGGCC GGTGCCATCTCAGGGCGCAGCTTCGAGCCGATCATGGCCATCCTGCTATTCTCGTGCACG CTGGCCCTGCACGCCCGGCAGGTGGATGTCAAGCTGCGGCTGGACTACCTCTGGGCGGCC CAGGCAGAGGAGGAGCGGGATGACATGGAGAAAGTGAAGCTGGACAACAAGAGGATTCTC TTCAACCTCCTGCCAGCCCACGTTGCCCAGCACTTCCTAATGTCCAACCCTCGCAACATG GACCTGTATTACCAGTCATACTCGCAGGTGGGGGTCATGTTTGCATCCATCCCCAACTTC AATGACTTCTACATCGAGCTGGATGGCAACAACATGGGGGTGGAATGTCTACGCCTTCTG AATGAGATCATCGCTGACTTTGATGAGCTCATGGACAAAGACTTTTACAAGGACCTAGAG AAGATCAAGACCATTGGGAGCACGTACATGGCTGCTGTGGGGCTGGCGCCCACTGCTGGG ACCAAGGCTAAGAAGTGCATCTCCTCCCACCTCAGCACGTTGGCAGATTTTGCCATCGAG ATGTTTGATGTCCTGGATGAGATCAACTACCAGTCTTATAACGACTTTGTGCTCCGTGTT GGCATCAATGTTGGCCCCGTGGTGGCTGGAGTGATCGGGGCTCGCAGGCCGCAGTATGAC ATTTGGGGGAACACGGTCAATGTGGCCAGTCGGATGGACAGTACCGGCGTCCAGGGCAGG ATCCAGGTCACAGAGGAAGTTCACCGGCTGCTGCGGCGGGGTTCCTACCGCTTCGTGTGC CGAGGCAAAGTCAGTGTCAAGGGCAAGGGTGAGATGCTGACATACTTCCTGGAAGGCAGG ACCGATGGAAATGGCTCCCAAACCAGGTCCCTGAACTCAGAGCGGAAAATGTATCCTTTC GGAAGAGCTGGCCTCCAGACCAGACTGGCTGCGGGTCACCCCCCGGTACCTCCTGCAGCC GGCCTCCCAGTTGGAGCTGGGCCAGGGGCTCTGCAGGGCTCGGGGCTTGCCCCAGGCCCC CCAGGCCAACACCTGCCCCCTGGAGCCTCTGGGAAGGAGGCTTAG |
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| Protein Properties | |||
| Number of Residues | 1134 | ||
| Molecular Weight | 123979.0 | ||
| Theoretical pI | 8.42 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Adenylate cyclase type 1 MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGIFVRILAERA QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA LRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV LPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA GAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPF GRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA |
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| External Links | |||
| GenBank ID Protein | AAA79957.1 | ||
| UniProtKB/Swiss-Prot ID | P19754 | ||
| UniProtKB/Swiss-Prot Entry Name | ADCY1_BOVIN | ||
| PDB IDs | |||
| GenBank Gene ID | M25579 | ||
| GeneCard ID | ADCY1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||