| Identification |
|---|
| BMDB Protein ID
| BMDBP00445 |
| Secondary Accession Numbers
| None |
| Name
| Diphosphoinositol polyphosphate phosphohydrolase 3-beta |
| Synonyms
|
Not Available
|
| Gene Name
| NUDT11 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| NUDT11 |
| Gene Sequence
|
>804 bp
ATGAAGTGCAAGCCGAACCAGACGCGGACCTACGACCCGGAGGGGTTCAAGAAGCGGGCG
GCGTGCCTGTGCTTCCGGAGCGAGCGCGAGGACGAGGTGCTGTTAGTGAGTAGCAGTCGG
TACCCGGACCGCTGGATCGTGCCGGGCGGGGGCATGGAGCCCGAGGAGGAGCCGGGCGGT
GCGGCCGTCCGCGAGGTGTTTGAAGAAGCGGGAGTCAAGGGGAAGTTAGGCCGGCTCCTG
GGCAATTTCGAGCAGAACCAAGATCGCAAGCACAGAACGTACGTGTATGTACTGACTGTC
ACTGAGATTCTGGAGGATTGGGAAGATTCGGTTAGCATTGGGAGGAAGCGAGAGTGGTTC
AAAGTCGAAGATGCGATCAAGGTTCTCCAGTGCCACAAGCCCGTGCATGCCGAATATCTG
CAAAAACTAAAGCTGGGCGGTTCCCCAACCAATGGAAACTCCGTGGCCCCGTCCCCCGCC
GGAGGGCGATCCCTAGTGAATGGCATAGATGTTCAGATTTACTTTGAAAGAATCAAGTAT
ATGAACCCAGTGATGAATGGAATTATGAAGACAGGTGAGCTCTTTCACACTCCCAAGGAC
ACAGCTCGTCCTATCCTTTTGGACACTTCCTCCCTGTTTATTGCAATGACTATTCTCCAG
GTTGTTGCACTACTTCTGTATCTGTACAGACTTCTAATTTGGCACCTATGGCCTTCTTTG
TGCTCTTATGATTATGTGTCTGTATTTCCCACCAGGTTATGTGACCTTGAGTGCAAAGAC
CTTATTTCTTTCATCTTTTTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 164 |
| Molecular Weight
| 18519.0 |
| Theoretical pI
| 6.28 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Diphosphoinositol polyphosphate phosphohydrolase 3-beta
MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGG
AAVREVFEEAGVKGKLGRLLGNFEQNQDRKHRTYVYVLTVTEILEDWEDSVSIGRKREWF
KVEDAIKVLQCHKPVHAEYLQKLKLGGSPTNGNSVAPSPPEGDP
|
| External Links |
|---|
| GenBank ID Protein
| AAX46684.1 |
| UniProtKB/Swiss-Prot ID
| Q58CW0 |
| UniProtKB/Swiss-Prot Entry Name
| NUD11_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT021837 |
| GeneCard ID
| NUDT11 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
