Showing Protein Endonuclease G, mitochondrial (BMDBP00450)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00450 |
| Secondary Accession Numbers | None |
| Name | Endonuclease G, mitochondrial |
| Synonyms | Not Available |
| Gene Name | ENDOG |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Nucleotide transport and metabolism |
| Specific Function | Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 11 |
| Locus | Not Available |
| SNPs | ENDOG |
| Gene Sequence |
>900 bp ATGCAGTTGCTTCGGGCCGGCTTGACTCTGGCCCTGGGCGCAGGGCTGGGTGCAGCTGCC GAGAGCTGGTGGCGACAGCGGGCGGACGCGCGGGCGACGCCGGGGCTGCTGAGCCGGCTG CCGGTGCTGCCAGTGGCGGCGGCGGCGGGGCTTCCCGCGGTGCCAGGGGCTCCCGCGGGT GGCGGCCCGGGCGAGTTAGCCAAGTATGGGCTGCCCGGGGTGGCGCAACTCAAGAGCCGC GCGTCGTACGTGCTGTGTTACGACCCGCGCACCCGCGGCGCGCTCTGGGTGGTCGAGCAG CTGCGGCCCGAGGGGCTCCGCGGCGACGGCAACCGCAGCTCCTGCGACTTCCACGAGGAC GACTCGGTGCATGCGTACCACCGCGCCACCAACGCCGATTACCGCGGCAGCGGCTTCGAC CGCGGCCACCTCGCTGCCGCGGCCAACCACCGCTGGAGCCAGAAGGCAATGGACGACACC TTCTACCTGAGCAACGTCGCGCCCCAGGTGCCACACCTCAACCAAAATGCCTGGAACAAC CTGGAAAAGTACAGCCGCAGTCTGACCCGCACCTACCAAAATGTCTATGTCTGCACCGGG CCACTCTTCCTGCCCAGGACGGAGGCTGATGGGAAGTCCTACGTGAAGTACCAAGTCATT GGCAAGAACCACGTGGCGGTGCCCACCCACTTCTTCAAGGTGCTGATCCTGGAGGCGGCA GGTGGGCAGATAGAACTCCGCTCCTATGTGATGCCCAATGCGCCGGTGGATGAGGCAATC CCGCTGGAGCACTTCCTGGTGCCCATTGAGAGCATTGAGCGGGCCTCCGGGCTGCTCTTT GTGCCAAACATCCTGGCACGGGCGGGCAGCCTGAAGGCCATCACTGCTGGCAGCAAGTAA |
| Protein Properties | |
| Number of Residues | 299 |
| Molecular Weight | 32262.0 |
| Theoretical pI | 9.42 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Endonuclease G, mitochondrial MQLLRAGLTLALGAGLGAAAESWWRQRADARATPGLLSRLPVLPVAAAAGLPAVPGAPAG GGPGELAKYGLPGVAQLKSRASYVLCYDPRTRGALWVVEQLRPEGLRGDGNRSSCDFHED DSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPHLNQNAWNN LEKYSRSLTRTYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAA GGQIELRSYVMPNAPVDEAIPLEHFLVPIESIERASGLLFVPNILARAGSLKAITAGSK |
| External Links | |
| GenBank ID Protein | CAA51320.1 |
| UniProtKB/Swiss-Prot ID | P38447 |
| UniProtKB/Swiss-Prot Entry Name | NUCG_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | X72802 |
| GeneCard ID | ENDOG |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |