Showing Protein Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (BMDBP00454)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00454 |
| Secondary Accession Numbers | None |
| Name | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial |
| Synonyms | Not Available |
| Gene Name | IDH3G |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Energy production and conversion |
| Specific Function | Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | X |
| Locus | Not Available |
| SNPs | IDH3G |
| Gene Sequence |
>1179 bp ATGGCGCTGAAGGTGGCGACGGCCGCGGGCGGCGCTGTGAAGGCAGCGCTCAGGCCGGCC CTCCTCTGGCGTCCTTGGGAGGTTCTAGGTTCCCACGAGGCCCCCCGGAGGAGCTTCTCA CAACAAACAATTCCCCCGTCGGCGAAGTATGGTGGGCGGCACACGGTGACCATGATCCCG GGAGATGGCATTGGGCCAGAGCTCATGCTGCACGTCAAGTCAGTGTTCAGGCATGCATGT GTGCCTGTGGACTTTGAAGAGGTGCACGTGAGCTCCACCGCGGACGAGGAGGACATCCGC AATGCCATCATGGCCATCCGTCGGAACCGCGTAGCCCTGAAGGGCAACATTGAAACAAAC CACAACCTGCCCCCATCCCACAAATCGCGAAACAACATCCTTCGCACCAGCCTGGACCTC TATGCCAACGTCATCCACTGTAAGAGCCTGCCAGGTGTGGTGACCCGGCATCGGGACATT GATATCCTCATTGTCCGGGAGAACACAGAGGGCGAGTACAGCAGCCTGGAACACGAGAGT GTGGCGGGCGTGGTGGAGAGCCTGAAGATCATCACCAAGGCCAAGTCCCTGCGTATTGCT GAGTACGCCTTCCAACTGGCCCAGGAGAGCGGGCGCAAGAAAGTGACAGCCGTGCACAAG GCCAACATCATGAAACTGGGCGATGGGCTTTTCCTCCAGTGCTGCAGGGAAGTGGCAGCC CGCTACCCCCAGATCACCTTTGAGAATATGATTGTGGACAACACCACCATGCAGCTGGTG TCCCGGCCCCAGCAGTTTGATGTCATGGTGATGCCCAATCTCTATGGCAACATCGTCAAC AACGTCTGTGCTGGGCTAGTTGGGGGCCCCGGCCTTGTGGCTGGGGCCAACTATGGCCAT GTGTATGCCGTGTTTGAGACGGCTACAAGGAACACAGGGAAGAGTATTGCCAATAAGAAC ATTGCCAACCCCACAGCTACACTGCTGGCAAGTTGCATGATGCTCGACCACCTCAAGCTG CACTCCTATGCCACCTCCATCCGCAAGGCCGTCCTGGCATCCATGGACAATGAAAACATG CACACCCCAGACATCGGGGGCCAGGGCACCACGTCGGAAGCCATCCAGGACATCATCCGC CATATCCGTGTCATTAACGGTCGGGCCGTGGAGGCCTAG |
| Protein Properties | |
| Number of Residues | 392 |
| Molecular Weight | 42863.0 |
| Theoretical pI | 9.16 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial MALKVATAAGGAVKAALRPALLWRPWEVLGSHEAPRRSFSQQTIPPSAKYGGRHTVTMIP GDGIGPELMLHVKSVFRHACVPVDFEEVHVSSTADEEDIRNAIMAIRRNRVALKGNIETN HNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHRDIDILIVRENTEGEYSSLEHES VAGVVESLKIITKAKSLRIAEYAFQLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAA RYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGH VYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENM HTPDIGGQGTTSEAIQDIIRHIRVINGRAVEA |
| External Links | |
| GenBank ID Protein | AAX46754.1 |
| UniProtKB/Swiss-Prot ID | Q58CP0 |
| UniProtKB/Swiss-Prot Entry Name | IDH3G_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BT021907 |
| GeneCard ID | IDH3G |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |