Showing Protein Inositol monophosphatase 1 (BMDBP00456)
| Identification | |||
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| BMDB Protein ID | BMDBP00456 | ||
| Secondary Accession Numbers |
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| Name | Inositol monophosphatase 1 | ||
| Synonyms | Not Available | ||
| Gene Name | IMPA1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Carbohydrate transport and metabolism | ||
| Specific Function | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates (By similarity). Is equally active with myo-inositol monophosphate and D-galactose 1-phosphate. | ||
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 14 | ||
| Locus | Not Available | ||
| SNPs | IMPA1 | ||
| Gene Sequence |
>834 bp ATGGCTGATCCTTGGCAGGAATGCATGGATTATGCAGTAACCCTGGCAGGACAAGCTGGA GAGGTGGTTCGTGAAGCGCTCAAGAATGAAATGAATATTATGGTTAAAAGTTCTCCGGCT GATTTGGTAACTGCTACTGACCAAAAAGTTGAAAAAATGCTTATCACATCCATAAAGGAA AAGTATCCATCTCACAGTTTCATTGGTGAGGAATCTGTGGCAGCTGGGGAAAAAAGTATC TTAACCGACAACCCTACATGGATCATTGACCCTATTGATGGAACAACTAACTTTGTACAT GGATTTCCTTTTGTAGCTGTTTCAATTGGCTTTGTGGTAAATAAAAAGATGGAGTTTGGA ATTGTGTACAGTTGCCTGGAGGATAAGATGTACACTGGCCGGAAAGGAAAAGGTGCCTTT TGTAATGGTCAAAAACTACAGGTTTCACACCAAGAAGATATTACCAAATCTCTCTTGGTG ACAGAGTTGGGCTCTTCCAGAACACCAGAGACTGTGAGAATTATTCTTTCTAATATAGAA AGGCTTCTTTGCCTTCCCATCCATGGGATCCGGGGTGTTGGAACAGCAGCTCTGAACATG TGCCTGGTGGCCGCTGGGGCTGCGGACGCGTATTATGAAATGGGGATCCACTGCTGGGAT GTTGCAGGCGCCGGCATCATTGTGACTGAAGCTGGCGGAGTGCTCCTGGATGTCACAGGT GGACCATTTGATTTGATGTCACGAAGAGTAATTGCTTCAAGCAATAAAACATTAGCAGAA AGGATAGCCAAAGAAATTCAGATAATACCTCTTCAAAGAGATGATGAAGATTAA |
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| Protein Properties | |||
| Number of Residues | 277 | ||
| Molecular Weight | 30056.0 | ||
| Theoretical pI | 4.81 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Inositol monophosphatase MADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKE KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFG IVYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIE RLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTG GPFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDED |
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| External Links | |||
| GenBank ID Protein | AAA30589.1 | ||
| UniProtKB/Swiss-Prot ID | P20456 | ||
| UniProtKB/Swiss-Prot Entry Name | IMPA1_BOVIN | ||
| PDB IDs | |||
| GenBank Gene ID | J05394 | ||
| GeneCard ID | IMPA1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||