Showing Protein DNA polymerase beta (BMDBP00472)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00472 |
| Secondary Accession Numbers | None |
| Name | DNA polymerase beta |
| Synonyms | Not Available |
| Gene Name | POLB |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Replication, recombination and repair |
| Specific Function | Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 27 |
| Locus | Not Available |
| SNPs | POLB |
| Gene Sequence |
>1008 bp ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGCATCACCGACATGCTCACA GAACTCGCAAACTTTGAGAAGAACGTGAACCAGGCTATCCACAAATACAATGCCTACAGA AAAGCAGCATCTGTGATAGCAAAGTACCCACACAAAATAAAGAGTGGAGCGGAAGCTAAG AAACTGCCTGGAGTAGGAACAAAAATTGCTGAAAAAATTGATGAGTTTTTAGCTACTGGA AAATTGCGTAAACTGGAAAAGATTCGGCAGGATGATACGAGTTCATCCATCAATTTCCTG ACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAG ACATTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAACGAATTGGGCTA AAATATTTTGAGGACTTTGAGAAAAGAATTCCTCGTGAAGAAATGTTACAAATGCAAGAT ATTGTACTAAGTGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTCCTTCTCACCCATCCAAGCTTT ACCTCTGAGTCAGCCAAACAGCCCAAACTGTTACATCGTGTTGTGGAGCAGTTACAAAAG GTCCGTTTCATTACAGACACTCTGTCAAAGGGTGAAACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAACGATGAAAAGGAATATCCACACAGGAGAATTGATATCAGGTTGATA CCCAAGGATCAGTATTACTGCGGTGTCCTCTATTTCACTGGGAGTGATATTTTCAATAAG AATATGAGAGCTCATGCCCTAGAAAAAGGCTTCACAATCAATGAATACACAATCCGTCCC CTGGGTGTCACTGGCGTTGCCGGGGAGCCCCTGCCCGTGGACAGTGAGAAGGACATCTTC GACTACATCCAGTGGAAATACCGTGAGCCCAAGGACCGAAGCGAGTGA |
| Protein Properties | |
| Number of Residues | 335 |
| Molecular Weight | 38267.0 |
| Theoretical pI | 9.53 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>DNA polymerase beta MSKRKAPQETLNGGITDMLTELANFEKNVNQAIHKYNAYRKAASVIAKYPHKIKSGAEAK KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLSEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESAKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE |
| External Links | |
| GenBank ID Protein | AAI03230.1 |
| UniProtKB/Swiss-Prot ID | Q27958 |
| UniProtKB/Swiss-Prot Entry Name | DPOLB_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC103229 |
| GeneCard ID | POLB |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |