| Identification |
|---|
| BMDB Protein ID
| BMDBP00486 |
| Secondary Accession Numbers
| None |
| Name
| Nucleoside diphosphate kinase 7 |
| Synonyms
|
Not Available
|
| Gene Name
| NME7 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). |
| Pathways
|
- Purine Metabolism
- Pyrimidine Metabolism
|
| Reactions
|
| Adenosine triphosphate + Guanosine diphosphate → ADP + Guanosine triphosphate |
details
|
| Adenosine triphosphate + dGDP → ADP + dGTP |
details
|
| Adenosine triphosphate + IDP → ADP + Inosine triphosphate |
details
|
| Uridine triphosphate + ADP → Uridine 5'-diphosphate + Adenosine triphosphate |
details
|
| Cytidine triphosphate + ADP → CDP + Adenosine triphosphate |
details
|
| dCDP + Adenosine triphosphate → dCTP + ADP |
details
|
| dTDP + Adenosine triphosphate → Thymidine 5'-triphosphate + ADP |
details
|
| Deoxyuridine triphosphate + ADP → dUDP + Adenosine triphosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 16 |
| Locus
| Not Available |
| SNPs
| NME7 |
| Gene Sequence
|
>1134 bp
ATGAATCATAGTGAGAGGTTCGTTTTCATCGCAGAGTGGTTTGATCCAAATGCTTCACTA
TTTCGACGTTATGAACTTTTATTTTACCCCGGGGATGGATCTGTTGAAATGCATGATGTA
AAGAATCATCGCACCTTTTTAAAGCGGACAAAATATGAAGATCTTCACCTGGAAGATTTA
TTTATAGGCAACAAAGTGAACATCTTTTCTCGACAACTGGTGCTGCTTGACTATGGAGAT
CAATACACAGCTCGTCAACTGGGCAGTAAGAAAGAAAAAACATTAGCCCTGATTAAACCA
GATGCAGTATCAAAAGCTGGAGAAATAATTGAAATAATAAACAAAGCTGGATTTACTCTA
ACCAAACTCAAAATGATGACGCTATCAAGGAAAGAAGCAACAGATTTTCATATAGACCAT
CAGTCAAGGCCCTTTTTAAATGAGCTGATCCAGTTTATTACAAGTGGACCTATAATTGCC
ATGGAGATTTTACGAGATGATGCTGTATGTGAATGGAAGAGACTTCTTGGACCTGCGAAC
TCTGGACTGGCACGTACAGATGCTCCTGAAAGCATTAGAGCCCTCTTTGGAACAGATGGC
ATAAAGAATGCAGCTCATGGCCCCGATTCTTTTGCTTGTGCTGCCAGAGAAATGGAGTTA
TTTTTTCCTTCAAGTGGAGTGTGTGGGCCAGCAAACACTGCTAAATTTACTAATTGTACT
ACTTGTTGCATTGTTAAGCCCCATGCTGTCAGCGAAGGACTTCTGGGAAAGATCCTGATG
ACTATCCGAGATGCAGGTTTTGAAATCTCAGCTATGCAGATGTTTAACATGGATCGGATT
AATGTTGAAGAGTTTTATGAAGTTTATAAAGGAGTAGTGTCTGAGTATAATGAAATGGTG
ACAGAAATGTATTCTGGGCCTTGTGTAGCAATGGAGATTCAACAAACTAATCCTACAATG
ACATTTCGAGAATTCTGTGGACCTGCTGATCCTGAAATTGCCCGACATTTACGCCCTGGA
ACCCTCCGAGCAATCTTTGGTAAAACTAAGATCCAGAATGCTGTTCACTGTACGGATCTG
CCAGAAGATGGTCTATTAGAGGTTCAGTATTTCTTCAAAATCTTGGATAACTAG
|
| Protein Properties |
|---|
| Number of Residues
| 377 |
| Molecular Weight
| 42599.0 |
| Theoretical pI
| 6.02 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Nucleoside diphosphate kinase 7
MNHSERFVFIAEWFDPNASLFRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYEDLHLEDL
FIGNKVNIFSRQLVLLDYGDQYTARQLGSKKEKTLALIKPDAVSKAGEIIEIINKAGFTL
TKLKMMTLSRKEATDFHIDHQSRPFLNELIQFITSGPIIAMEILRDDAVCEWKRLLGPAN
SGLARTDAPESIRALFGTDGIKNAAHGPDSFACAAREMELFFPSSGVCGPANTAKFTNCT
TCCIVKPHAVSEGLLGKILMTIRDAGFEISAMQMFNMDRINVEEFYEVYKGVVSEYNEMV
TEMYSGPCVAMEIQQTNPTMTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL
PEDGLLEVQYFFKILDN
|
| External Links |
|---|
| GenBank ID Protein
| AAX08797.1 |
| UniProtKB/Swiss-Prot ID
| Q5E9Y9 |
| UniProtKB/Swiss-Prot Entry Name
| NDK7_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020780 |
| GeneCard ID
| NME7 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
