| Identification |
|---|
| BMDB Protein ID
| BMDBP00488 |
| Secondary Accession Numbers
| |
| Name
| 2-hydroxyacyl-CoA lyase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| ILVBL |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway. |
| Pathways
|
Not Available
|
| Reactions
|
| 2-Hydroxyphytanoyl-CoA → Pristanal + Formyl-CoA |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| ILVBL |
| Gene Sequence
|
>1920 bp
ATGAGAAGCAGGTGTCAGCTCATGGAGACCGCGGTGGCTGCCGCCCCAGTTTGGGGCTTC
TTCTCCTCTTTTCTGCTCCTGGCCTTTGGGACGCTAGTGGCCGCCTTGCTGGGCGCCGCT
CACCGCCTGGGGCTCTTCTATCAGTTGATGCACAAGGTGGACACGGCAAGCACCCGGCAT
GGTGGGGAAAATGTGGCAGCCGTGCTGAAGGCCCACGGTGTGCGCTTCCTTTTCACACTG
GTCGGCGGGCACATTTCGCCACTGCTGGTGGCCTGTGAGAAGTTGGGCATCCGCGTGGTG
GACACCCGCCACGAAGTCACAGCTGTCTTTGCCGCTGATGCTGTAGCCCGCCTGACCGGG
ACAGTGGGCGTGGCTGCAGTGACGGCCGGTCCCGGCCTCACCAACACAGTGACTGCGGTG
AAGAATGCCCAGATAGCCCAGTCCCCAGTCCTGCTCCTGGGTGGGGCTGCCAGCACCCTG
CTGCAGAATCGGGGTGCACTCCAGGCAATTGATCAGATAGCCCTGTTCCGGCCGCTCTGC
AAGTTTTGTGCTTCTGTGCGGAGAGTGCGGGATATCATCCCCACCCTGAGGGCTGCGATG
GCCGCTGCACAGTCGGGCACCCCCGGCCCGGTGTTTGTGGAACTGCCTCTGGACGTGCTG
TACCCCTACTTCATGGTTCAGAAGGAGATGGTGCCAGCTAAGCCGCCCAAGGGCCTCATG
AGTCGAGCGGTCCACTGGTACTTGGCGAATTCCCTGGCCAACCTCTTTGCAGGAGCTTGG
GAGCCTCAGCCTGAGGGGCCTCTGCCCCTGGACATTCCCCAGGCCTCCCCCCAGCAGGTT
CAGCGATGTGTGGAGATCTTGAGTCGGGCCAAAAAGCCCCTCATGCTAATTGGGAGCCAG
GCCCTGCTGCCTCCGACATCCTCAGACAAGCTTCGGGTTGCCGTGGAGACCCTGGGCATC
CCTTGCTTCCTGGCGGGGATGGCACGGGGACTGCTGGGCCGCAACCACCCCCTCCATTTC
CGGCAGAACCGCAGGGCTGCCCTGAAGAAGGCAGACGTGGTCGTCCTGGCAGGAGCAGTG
TGTGACTTCCGCCTGTCCTATGGGCGTGTCCTCAGCCGCAGCAGCAAAATCATTGTTGTC
AACCGTGACCGGAAGGAGATGCTGATCAACTCAGACATTTTCTGGAAGCCCCAAGAGGCT
GTGCAGGGAGATGTGGGCTCCTTCGTGGTGAAGCTGGTGGAGGGCCTCCGGGGTCAGATG
TGGGCCTCAGACTGGGCAGAGGAGCTTCGGCAAGCCGACCAACAGAAGGAGCAGGCCTTT
CGGGAGAAGGCACTGATGCCCGTAGCCCAGCATCTTAACCCGGTGCGGGTCCTGCAGCTG
GTGGAGGACACTCTGCCTGACAACTCCATCCTGGTGGTTGATGGCGGGGACTTCGTGGGC
ACAGCTGCCTACCTGGTGCAGCCCCGTGGGCCCTTGCGTTGGCTTGATCCTGGGGCCTTT
GGGACTCTGGGGGTTGGTGCCGGATTTGCACTTGGGGCCAAACTGTGTCGGCCGGATGCG
GAGGTCTGGTGCTTGTTTGGGGATGGAGCGTTTGGCTATAGCCTCATCGAATTTGACACC
TTCGTCAGACACAAGATCCCAGTGATGGCCTTGATAGGAAATGATGCTGGCTGGACCCAG
ATTTCCAGGGAGCAGGTGCCCTCTCTGGGCAGCAATGTGGCCTGTGGCTTGGCTTACACT
GATTATCACAAGGCAGCCCAGGGACTGGGGGCCCAGGGCTTGCTGCTGTCACGCGAGAAT
GAGGATCAGGTGGTCAAGGTGCTGCGTGACGCCCAGCAGTGGTGCCAGGATGGCCACCCG
GTTGTGGTCAACATTCTCATCGGGAGGACGGACTTCCGGGACGGCTCCATCGCCATGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 632 |
| Molecular Weight
| 68110.0 |
| Theoretical pI
| 8.96 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Acetolactate synthase-like protein
METAVAAAPAWGFFSSFLLLAFGTLVAALLGAAHRLGLFYQLMHKVDTASTRHGGENVAA
VLKAHGVRFLFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAVARLTGTVGVAAV
TAGPGLTNTVTAVKNAQIAQSPVLLLGGAASTLLQNRGALQAIDQIALFRPLCKFCASVR
RVRDIIPTLRAAMAAAQSGTPGPVFVELPLDVLYPYFMVQKEMVPAKPPKGLMSRAVHWY
LANSLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKKPLMLIGSQALLPPTS
SDKLRVAVETLGIPCFLAGMARGLLGRNHPLHFRQNRRAALKKADVVVLAGAVCDFRLSY
GRVLSRSSKIIVVNRDRKEMLINSDIFWKPQEAVQGDVGSFVVKLVEGLRGQMWASDWAE
ELRQADQQKEQAFREKALMPVAQHLNPVRVLQLVEDTLPDNSILVVDGGDFVGTAAYLVQ
PRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIP
VMALIGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAQGLGAQGLLLSRENEDQVVKV
LRDAQQWCQDGHPVVVNILIGRTDFRDGSIAM
|
| External Links |
|---|
| GenBank ID Protein
| AAX08821.1 |
| UniProtKB/Swiss-Prot ID
| A6QQT9 |
| UniProtKB/Swiss-Prot Entry Name
| HACL2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020804 |
| GeneCard ID
| ILVBL |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
