Identification
BMDB Protein ID BMDBP00503
Secondary Accession Numbers None
Name Nucleoside diphosphate kinase A 1
Synonyms Not Available
Gene Name NME1-1
Protein Type Enzyme
Biological Properties
General Function Nucleotide transport and metabolism
Specific Function Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 19
Locus Not Available
SNPs NME1-1
Gene Sequence
>459 bp
ATGGCCAACAGCGAGCGCACCTTCATTGCCATCAAGCCCGATGGAGTCCAGCGAGGCCTC
ATTGGAGAAATAATCAAGCGTTTTGAGCAAAAGGGATTCCGTCTTGTTGCCATGAAATTC
ATGCGGGCTTCTGAAGACCTTCTCAAGGAGCACTATATTGACCTGAAGGACCGTCCATTC
TTTGCTGGCCTGGTGAAATACATGCACTCAGGGCCAGTGGTTGCCATGGTCTGGGAGGGA
CTGAATGTTGTGAAGACAGGTCGAGTGATGCTTGGGGAGACTAACCCTGCGGACTCCAAG
CCTGGGACCATCCGTGGGGACTTTTGCATCCAAGTTGGCAGGAACATTATCCATGGCAGT
GATTCCGTGGAGAGTGCAGAGAAGGAGATTGCCTTGTGGTTTCACCCTGAGGAACTGGTG
AATTACAAGAGCTGTGCTCAGAACTGGATCTACGAGTGA
Protein Properties
Number of Residues 152
Molecular Weight 17261.0
Theoretical pI 7.58
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Nucleoside diphosphate kinase A 1
MANSERTFIAIKPDGVQRGLIGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPF
FAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGS
DSVESAEKEIALWFHPEELVNYKSCAQNWIYE
GenBank ID Protein CAA63532.1
UniProtKB/Swiss-Prot ID P52174
UniProtKB/Swiss-Prot Entry Name NDKA1_BOVIN
PDB IDs
GenBank Gene ID X92956
GeneCard ID NME1-1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available