| Identification |
|---|
| BMDB Protein ID
| BMDBP00516 |
| Secondary Accession Numbers
| |
| Name
| Isocitrate dehydrogenase [NADP] cytoplasmic |
| Synonyms
|
Not Available
|
| Gene Name
| IDH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Energy production and conversion |
| Specific Function
| May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. |
| Pathways
|
Not Available
|
| Reactions
|
| Isocitric acid + NADP → Oxoglutaric acid + NADPH + Carbon dioxide |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| IDH1 |
| Gene Sequence
|
>1245 bp
ATGTCTCAAAAAATCCAAGGCGGGTCTGTGGTAGAGATGCAAGGAGATGAAATGACACGG
ATCATTTGGGAGTTGATTAAAGAGAAACTCATTTTTCCCTACGTGGAACTGGACCTGCAC
AGCTACGATTTAGGCATAGAGAATCGCGATGCCACCAACGACCAGGTCACCAAGGACGCT
GCAGAAGCTATAAAGAAGTACAACGTTGGTGTCAAGTGTGCCACCATCACCCCCGATGAG
AAGAGAGTGGAGGAATTCAAGTTGAAACAAATGTGGAAGTCTCCAAATGGCACCATCCGA
AATATCCTGGGTGGCACTGTCTTCAGGGAAGCTATTATCTGCAAAAATATACCCCGGCTT
GTGAGCGGATGGGTAAAACCCATTATCATAGGTCGTCATGCTTATGGGGATCAATATAGA
GCAACCGATTTTGTTGTGCCAGGGCCTGGAAAAGTAGAGATATCCTACACACCAAGCGAT
GGATCCCCCAAAACGGTATACCTAGTACATAACTTCACAGAGAGTGGTGGTGTTGCCATG
GGGATGTACAATCAAGATAAGTCAATCGAAGATTTTGCGCACAGTTCTTTCCAGATGGCT
TTGTCTAAGAACTGGCCTTTGTATCTGAGCACCAAAAACACTATTCTGAAGAAATACGAT
GGACGTTTTAAAGACATCTTTCAGGAGATATATGACAAGCAGTACAAATCTGAGTTTGAA
GCTCAGAATATCTGGTATGAGCACAGGCTCATTGATGACATGGTGGCCCAAGCTATGAAA
TCGGAGGGGGGCTTCATTTGGGCCTGTAAGAACTATGATGGGGACGTGCAGTCGGACTCC
GTGGCCCAAGGTTATGGCTCTCTCGGCATGATGACCAGTGTGCTGGTTTGTCCAGATGGC
AAGACAGTAGAAGCAGAGGCTGCCCACGGGACTGTAACCCGTCACTACCGAATGTACCAG
AAAGGACAGGAGACATTGACCAATCCCATTGCTTCCATTTTTGCCTGGACCAGAGGCTTA
GCCCACAGAGCTAAGCTTGATAACAATAAAGAGCTCAGCTTTTTTGCAAAGGCTTTGGAA
GAAGTCTGTATTGAGACCATTGAGGCTGGCTTCATGACCAAGGACTTAGCTGCATGTATT
AAAGGTTTACCCAACGTGCAACGTTCTGACTACTTGAATACATTTGAGTTCATGGATAAA
CTCGGAGAGAACCTGCAGTTAAAACTAGCCCAGGCCAAACTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 414 |
| Molecular Weight
| 46785.0 |
| Theoretical pI
| 6.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Isocitrate dehydrogenase [NADP] cytoplasmic
MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM
GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE
AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL
|
| External Links |
|---|
| GenBank ID Protein
| AAD34457.1 |
| UniProtKB/Swiss-Prot ID
| Q9XSG3 |
| UniProtKB/Swiss-Prot Entry Name
| IDHC_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| AF136009 |
| GeneCard ID
| IDH1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
