Identification
BMDB Protein ID BMDBP00525
Secondary Accession Numbers None
Name Adenylosuccinate synthetase isozyme 2
Synonyms Not Available
Gene Name ADSS2
Protein Type Enzyme
Biological Properties
General Function Nucleotide transport and metabolism
Specific Function Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Pathways
  • AMP biosynthesis via de novo pathway
  • AMP from IMP: step 1/2
  • Purine Metabolism
Reactions
Guanosine triphosphate + Inosinic acid + L-Aspartic acid → Guanosine diphosphate + Hydrogen phosphate + Adenylsuccinic acid details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
SNPs ADSS2
Gene Sequence Not Available
Protein Properties
Number of Residues 456
Molecular Weight 50156.0
Theoretical pI 6.72
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Adenylosuccinate synthetase isozyme 2
MAFAETNPATSSLPNGDCGRPRTRPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC
QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL
EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR
MCDLVSDFGGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMERIKPMVRDGVYFLYE
ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY
TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL
TKLDILDMFTEIKVGVAYKLDGEIIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKE
LPINAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF
GenBank ID Protein AAI51542.1
UniProtKB/Swiss-Prot ID A7MBG0
UniProtKB/Swiss-Prot Entry Name PURA2_BOVIN
PDB IDs Not Available
GenBank Gene ID BC151541
GeneCard ID ADSS2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available