Identification
BMDB Protein ID BMDBP00529
Secondary Accession Numbers
  • BMDBP03098
Name Acetylcholinesterase
Synonyms Not Available
Gene Name ACHE
Protein Type Enzyme
Biological Properties
General Function Lipid transport and metabolism
Specific Function Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Pathways Not Available
Reactions
Acetylcholine → Choline details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 25
Locus Not Available
SNPs ACHE
Gene Sequence
>1842 bp
ATGAGGCCCCCGTGGTGTCCCCTGCACACGCCCTCCCTGACTCCCCCGCTCCTTCTCCTC
CTCTTCCTTCTGGGAGGAGGGGCAGAGGCCGAGGGCCCAGAGGACCCAGAGCTGCTGGTG
ATGGTGCGTGGGGGCCGACTGCGGGGTCTCCGCCTAATGGCCCCCAGGGGCCCTGTCTCT
GCTTTTCTGGGCATCCCCTTCGCAGAGCCACCTGTGGGCCCCCGTCGCTTTCTGCCACCA
GAGCCCAAGCGGCCCTGGCCAGGGGTGCTGAATGCCACGGCCTTCCAAAGCGTCTGCTAC
CAGTATGTGGACACCTTGTACCCCGGCTTTGAGGGCACTGAGATGTGGAACCCCAACCGT
GAGCTGAGTGAGGACTGCCTCTACCTCAACGTGTGGACACCGTACCCCCGGCCTTCGTCC
CCCACCCCTGTCCTCGTCTGGATCTATGGGGGTGGCTTCTACAGCGGGGCCTCCTCCCTG
GATGTGTACGATGGCCGTTTCCTGACCCAGGCTGAGGGGACTGTGCTGGTGTCCATGAAC
TACCGGGTGGGCGCCTTTGGCTTCTTGGCTCTGCCGGGGAGCCGGGAGGCCCCAGGCAAT
GTGGGGCTACTGGATCAGAGGCTGGCACTGCAGTGGGTGCAGGAGAATGTGGCAGCCTTC
GGGGGGGACCCAACGTCAGTGACTCTGTTTGGGGAAAGTGCAGGTGCCGCTTCTGTGGGC
ATGCACCTGCTGTCCCCACCCAGCCGGGGCCTGTTCCACAGGGCCGTGCTGCAGAGCGGG
GCACCCAATGGGCCCTGGGCCACGGTGGGCGTAGGAGAGGCCCGCCGGAGGGCCACACTG
CTGGCCCGCCTTGTGGGTTGTCCCCCGGGTGGGGCTGGTGGCAATGACACAGAGCTGGTG
GCCTGCCTGCGGGCACGGCCAGCTCAGGACCTGGTGGACCATGAGTGGCGCGTGCTGCCT
CAGGAAAGCGTCTTCCGCTTCTCCTTCGTGCCTGTGGTGGACGGAGACTTCCTCAGTGAC
ACACCCGAGGCCCTCATCAATGCTGGAGACTTCCATGGCCTGCAGGTGCTGGTGGGTGTG
GTGAAGGATGAGGGCTCCTATTTTCTGGTTTATGGGGCCCCAGGCTTCAGCAAAGACAAC
GAGTCTCTCATCAGCCGGGCCCAGTTCCTGGCCGGGGTGCGGGTCGGGGTCCCCCAGGCA
AGTGACCTGGCTGCCGAGGCTGTGGTCCTGCATTACACAGACTGGCTGCACCCTGAGGAC
CCAGCACGCCTGAGGGAGGCCTTGAGTGATGTGGTGGGTGACCACAACGTCGTGTGCCCC
GTGGCCCAGCTGGCTGGGCGACTGGCCGCTCAGGGCGCTCGTGTCTATGCCTACATCTTT
GAACACCGTGCATCCACGCTCTCCTGGCCCCTCTGGATGGGGGTGCCCCACGGCTACGAG
ATCGAGTTCATCTTCGGGCTCCCCCTGGAACCCTCGCTCAACTACACCATCGAGGAGAGA
ACCTTTGCCCAGCGACTGATGAGATACTGGGCCAACTTCGCCCGCACAGGAGACCCCAAT
GACCCCCGGGACCCCAAAGCCCCACAGTGGCCACCGTATACGGCGGGAGCGCAGCAGTAC
GTGAGCCTGAATCTGCGGCCTCTAGAGGTGCGGCGAGGGCTGCGAGCCCAGGCCTGCGCT
TTCTGGAATCGCTTCCTGCCCAAACTACTCAGCGCCACCGACACGCTGGACGAGGCGGAG
CGCCAGTGGAAGGCCGAGTTCCATCGCTGGAGCTCCTACATGGTGCACTGGAAGAACCAG
TTTGACCATTACAGCAAGCAGGATCGCTGCTCAGACCTGTGA
Protein Properties
Number of Residues 613
Molecular Weight 67664.0
Theoretical pI 6.07
Pfam Domain Function Not Available
Signals
  • 1-30
Transmembrane Regions Not Available
Protein Sequence
>Acetylcholinesterase
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
GenBank ID Protein AAC64270.1
UniProtKB/Swiss-Prot ID P23795
UniProtKB/Swiss-Prot Entry Name ACES_BOVIN
PDB IDs
GenBank Gene ID AF061815
GeneCard ID ACHE
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available