Showing Protein 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (BMDBP00549)
| Identification | |||||
|---|---|---|---|---|---|
| BMDB Protein ID | BMDBP00549 | ||||
| Secondary Accession Numbers | None | ||||
| Name | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | ||||
| Synonyms | Not Available | ||||
| Gene Name | HIBCH | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Lipid transport and metabolism | ||||
| Specific Function | Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity). | ||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 2 | ||||
| Locus | Not Available | ||||
| SNPs | HIBCH | ||||
| Gene Sequence |
>1161 bp ATGGGGTTGCAGGGGTTGTGCAGACTCATGTCGAGGTTTAATTCATATAAAAGGACTAAT ATCATACTGCAGCATTTGAAAATGTCTAATCACACAGATGCAGCAGCAGAAGTCCTGTTG GAAAGAAAAGGTTGTGCAGGAGTGATAACACTAAACAGACCAAGGTTTCTGAATACCCTG ACTCTTGGTATGATTCGGCAGATTTACGCACAGCTAAAGAAGTGGGAACAAGATCCGAAA ACTTTCCTGATCATCATAAAGGGAGCTGGTGAAAAGGCTTTCTGTGCTGGAGGTGATATC AGAGCACTCTCAGAAGCTAGAAATACAAACCAGAAAATGCTTCAAGATTTATTCCGAGAG GAATATATTCTGAACAATGCCATTGATTCTTGCCAGAAACCATATATTGCACTTATTCAT GGAATTACAATGGGTGGGGGAGTTGGTGTCTCAGTTCATGGGCAATTCCGAGTGGCTACC GAAAAGTCTGTTTTTGCGATGCCAGAAACAGCAATAGGGCTATTCCCTGATGTGGGTGGA GGTTATTTCTTGCCACGACTTCAAGGAAAACTTGGGTACTTCCTTGCATTAACAGGATTC AGGCTGAAAGGAAGAGATGTGTACACAGCAGGAATTGCTACACACTTCGTAGATTTTGAA AAGTTGGGCATGCTAGAAGAAGATTTGTTAGCCCTGAAATCTCCTTCAAAAGAAAATATT GCAGATGTCTTAGAAACTTACCATGCAAAGTCAAAGACTGATCAAGACAAGCCTTTTATA CTCGAGGAACACATGGACAAAATAAACAGTTGGTTCTCAGCTAATACTGTGGAACAGATT GTTGACAATTTACAGCAAGACGGCTCATCTTTTGCCCTGGAGCAGCTGAAGGTAATTAAA AAAATGTCTCCAACTTCACTAAAGATCACACTAAGGCAACTCATGGAGGGGTCTTCAAAG ACCTTGCCAGAAGTATTAATTATGGAATATCGGCTGAGTCAAGCTTGTATGAAAGGCCAT GACTTTCATGAAGGCGTTAGGGCAGTTTTAATAGATAAAGACCAGAGTCCAAAGTGGAAA CCAGCTGACCTAAAAGAAGTTACTGATGAAGATTTGAATGATTACTTCAAATCTCTGGGA AGTAATGATTTGAAATTTTGA |
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| Protein Properties | |||||
| Number of Residues | 386 | ||||
| Molecular Weight | 43349.0 | ||||
| Theoretical pI | 8.21 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>3-hydroxyisobutyryl-CoA hydrolase, mitochondrial MGLQGLCRLMSRFNSYKRTNIILQHLKMSNHTDAAAEVLLERKGCAGVITLNRPRFLNTL TLGMIRQIYAQLKKWEQDPKTFLIIIKGAGEKAFCAGGDIRALSEARNTNQKMLQDLFRE EYILNNAIDSCQKPYIALIHGITMGGGVGVSVHGQFRVATEKSVFAMPETAIGLFPDVGG GYFLPRLQGKLGYFLALTGFRLKGRDVYTAGIATHFVDFEKLGMLEEDLLALKSPSKENI ADVLETYHAKSKTDQDKPFILEEHMDKINSWFSANTVEQIVDNLQQDGSSFALEQLKVIK KMSPTSLKITLRQLMEGSSKTLPEVLIMEYRLSQACMKGHDFHEGVRAVLIDKDQSPKWK PADLKEVTDEDLNDYFKSLGSNDLKF |
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| External Links | |||||
| GenBank ID Protein | AAI13275.1 | ||||
| UniProtKB/Swiss-Prot ID | Q2HJ73 | ||||
| UniProtKB/Swiss-Prot Entry Name | HIBCH_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | BC113274 | ||||
| GeneCard ID | HIBCH | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||