Identification
BMDB Protein ID BMDBP00552
Secondary Accession Numbers None
Name Carboxypeptidase E
Synonyms Not Available
Gene Name CPE
Protein Type Enzyme
Biological Properties
General Function Amino acid transport and metabolism
Specific Function Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 17
Locus Not Available
SNPs CPE
Gene Sequence
>1428 bp
ATGGCCCGGCGAGGGGGCTGCGCGCTGCTGGTGCTGTGCGGCTCGCTGGCCGCCTGTGCC
TGGCTGCTGGGCGCCGAGGCCCGGGGGCCTGGGGGCCCTGTGGCGGGCGCAAGGCGGCGC
CGGCGGCCCCAGGAGGACGGCATCTCCTTTGAGTACCACCGCTACCCAGAGCTTCGTGAA
GCGCTCGTGTCCGTGTGGCTGCAGTGCGCCGCGGTCAGCAGGATCTACACGGTGGGGCGC
AGCTTCGAGGGCCGCGAGCTGCTGGTGCTCGAGCTGTCCGACAACCCCGGCGTCCACGAG
CCGGGTGAGCCTGAATTTAAATACATCGGGAATATGCATGGCAATGAAGCTGTCGGACGG
GAGCTGCTCATTTTTCTGGCCCAGTACCTGTGCAATGAGTACCAAAAAGGGAATGAGACA
ATTGTCCAGCTGATCCACAACACCCGAATCCACATCATGCCTTCTCTGAACCCTGATGGC
TTTGAAAAGGCAGCATCTCAGCTTGGTGAGCTGAAGGACTGGTTCGTGGGTCGAAGCAAT
GCCCAGGGAATAGATCTGAACCGGAACTTTCCCGACCTGGACAGAATAGTTTATATTAAT
GAGAAAGAAGGTGGTCCAAATAATCATCTGTTGAAAAATCTGAAGAAAATTGTGGATCAA
AACACAAAGCTTGCTCCTGAGACGAAGGCTGTCATTCATTGGATTATGGATATTCCTTTT
GTGCTCTCTGCCAATCTTCACGGAGGAGACCTTGTGGCCAATTATCCATATGATGAGACG
AGGAGTGGTAGTGCTCATGAATACAGCTCCTGCCCAGATGACGACATCTTCCAAAGCTTA
GCTCGGGCATACTCATCCTTCAACCCCCCAATGTCGGACCCAGATCGGCCCCCATGTCGC
AAGAATGATGATGACAGCAGCTTTGTAGAAGGAACGACCAATGGTGCTGCATGGTACAGC
GTGCCTGGAGGAATGCAAGATTTCAATTACCTCAGCAGCAACTGCTTTGAGATTACTGTG
GAGCTTAGCTGTGAAAAGTTTCCACCTGAAGAGACTTTGAAGAACTACTGGGAGGATAAC
AAAAACTCCCTCATTAGCTACATTCAGCAGATACACCGAGGAGTTAAAGGATTTGTCCGA
GATCTTCAGGGTAACCCAATTGCTAATGCCACCCTCTCTGTGGAAGGAATAGACCATGAT
GTCACATCTGCAAAGGATGGTGATTACTGGAGATTGCTCGTCCCTGGAAACTATAAACTT
ACAGCCTCAGCACCGGGCTATCTGGCAATAGCAAAGAAAGTGGCAGTTCCTTATAGCCCT
GCTGTCAGGGTTGATTTTGAACTGGAGTCATTTTCTGAAAGGAAAGAAGAAGAGAAGGAA
GAATTAATGGAATGGTGGAAGATGATGTCAGAAACTTTAAACTTTTAA
Protein Properties
Number of Residues 475
Molecular Weight 53309.0
Theoretical pI 4.94
Pfam Domain Function Not Available
Signals
  • 1-27
Transmembrane Regions Not Available
Protein Sequence
>Carboxypeptidase E
MARRGGCALLVLCGSLAACAWLLGAEARGPGGPVAGARRRRRPQEDGISFEYHRYPELRE
ALVSVWLQCAAVSRIYTVGRSFEGRELLVLELSDNPGVHEPGEPEFKYIGNMHGNEAVGR
ELLIFLAQYLCNEYQKGNETIVQLIHNTRIHIMPSLNPDGFEKAASQLGELKDWFVGRSN
AQGIDLNRNFPDLDRIVYINEKEGGPNNHLLKNLKKIVDQNTKLAPETKAVIHWIMDIPF
VLSANLHGGDLVANYPYDETRSGSAHEYSSCPDDDIFQSLARAYSSFNPPMSDPDRPPCR
KNDDDSSFVEGTTNGAAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKNYWEDN
KNSLISYIQQIHRGVKGFVRDLQGNPIANATLSVEGIDHDVTSAKDGDYWRLLVPGNYKL
TASAPGYLAIAKKVAVPYSPAVRVDFELESFSERKEEEKEELMEWWKMMSETLNF
GenBank ID Protein AAI42182.1
UniProtKB/Swiss-Prot ID P04836
UniProtKB/Swiss-Prot Entry Name CBPE_BOVIN
PDB IDs Not Available
GenBank Gene ID BC142181
GeneCard ID CPE
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available