Identification
BMDB Protein ID BMDBP00562
Secondary Accession Numbers None
Name Aspartoacylase
Synonyms Not Available
Gene Name ASPA
Protein Type Enzyme
Biological Properties
General Function Amino acid transport and metabolism
Specific Function Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity).
Pathways
  • Aspartate Metabolism
Reactions
N-Acetyl-L-aspartic acid + Water → Acetic acid + L-Aspartic acid details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 19
Locus Not Available
SNPs ASPA
Gene Sequence Not Available
Protein Properties
Number of Residues 313
Molecular Weight 35738.0
Theoretical pI 6.65
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Aspartoacylase
MTSCHVAEDPIKKVAIFGGTHGNELTGVFLVKHWLENSTEIQRTGLEVKPFITNPRAVKK
CTRYIDCDLNRVFDPENLGKKKSEDLPYEVRRAQEINHLFGPKDSEDSYDIIFDLHNTTS
NMGCTLILEDSRNDFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVG
PQPQGVLRADILDQMRKMIQHALDFIHNFNEGKEFPPCAIEVYKIMRKVDYPRNESGEIS
AIIHPKLQDQDWKPLHPEDPVFLTLDGKTIPLGGDQTVYPVFVNEAAYYEKKEAFAKTTK
LTLNANSIRSSLH
GenBank ID Protein AAD14980.1
UniProtKB/Swiss-Prot ID P46446
UniProtKB/Swiss-Prot Entry Name ACY2_BOVIN
PDB IDs Not Available
GenBank Gene ID S74726
GeneCard ID ASPA
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available