Showing Protein Isoaspartyl peptidase/L-asparaginase (BMDBP00565)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00565 | ||
| Secondary Accession Numbers | None | ||
| Name | Isoaspartyl peptidase/L-asparaginase | ||
| Synonyms | Not Available | ||
| Gene Name | ASRGL1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Amino acid transport and metabolism | ||
| Specific Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. | ||
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 29 | ||
| Locus | Not Available | ||
| SNPs | ASRGL1 | ||
| Gene Sequence |
>927 bp ATGAACCCCGTCGTCGTGGTCCACGGTGGCGGAGCCAGCAATATCTCCAAAGACCGGAAA GAGCGGGTGCGCCAGGGCATCCTCAGAGCCGCCACCGTGGGTTACAACATCCTCAAGCAG GGAGGGAGCGCCGTTGACGCGGTGGAAGGAGCCGTGACAGTGCTGGAAGACGATCCCGAC TTCAACGCAGGTTGTGGATCTGTCTTGAACGAAAACGGGGAGGTTGAAATGGATGCCAGT ATCATGAATGGGAAAGACCTGTCTGCAGGGGCGGTGTCTGCAGTCCGCTGTATCGCAAAT CCCATTAAACTTGCACGGCTTGTTATGGACAAGACACCTCACTGCTTTCTGACTGACCAA GGTGCAGCAAGATTTGCAGCAGCCAATGGGATTCCAACAATTCCTGGACAACAGCTGGTA ACAGAAAGAAGCAGAAAACGCCTGGAAAAAGAAAAGCTTGAAAAAGATGCTCAGAAACCA GACTGTCAGAAAAACTTGGGGACTGTGGGTGCTGTTGCCTTGGACTGCCAAGGAAACCTG GCTTATGCAACCTCAACAGGGGGCATCGTCAACAAGATGCCGGGCCGCGTCGGGGACACG CCGTGTGTAGGATCTGGAGGTTACGCTGACAATGACATCGGAGCTGTCTCAACGACAGGG CACGGTGAGAGCATCCTGAAGGTGAATCTGGCCAGACTCGCGCTCTTCCACGTTGAACAG GGAAAATCACTAGAAGAAGCTGCCAACGCATCACTGGGTCATATGAAGTCAAAGGTCAAG GGCGTAGGTGGTATCATCATGGTCAACAAAGCAGGAGAGTGGGCGGTGAAGTGGACCTCC ACATCCATGCCCTGGGCAGCGGCAAAGGATGGCAAGCTGCACTCGGGAATTGACTTCGGC GACACGAGCATCATTGACCTGTCCTAA |
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| Protein Properties | |||
| Number of Residues | 308 | ||
| Molecular Weight | 32050.0 | ||
| Theoretical pI | 7.47 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>L-asparaginase MNPVVVVHGGGASNISKDRKERVRQGILRAATVGYNILKQGGSAVDAVEGAVTVLEDDPD FNAGCGSVLNENGEVEMDASIMNGKDLSAGAVSAVRCIANPIKLARLVMDKTPHCFLTDQ GAARFAAANGIPTIPGQQLVTERSRKRLEKEKLEKDAQKPDCQKNLGTVGAVALDCQGNL AYATSTGGIVNKMPGRVGDTPCVGSGGYADNDIGAVSTTGHGESILKVNLARLALFHVEQ GKSLEEAANASLGHMKSKVKGVGGIIMVNKAGEWAVKWTSTSMPWAAAKDGKLHSGIDFG DTSIIDLS |
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| External Links | |||
| GenBank ID Protein | AAI09622.1 | ||
| UniProtKB/Swiss-Prot ID | Q32LE5 | ||
| UniProtKB/Swiss-Prot Entry Name | ASGL1_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | BC109621 | ||
| GeneCard ID | ASRGL1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||