Showing Protein Aspartate aminotransferase, mitochondrial (BMDBP00569)
| Identification | |||
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| BMDB Protein ID | BMDBP00569 | ||
| Secondary Accession Numbers |
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| Name | Aspartate aminotransferase, mitochondrial | ||
| Synonyms | Not Available | ||
| Gene Name | GOT2 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Amino acid transport and metabolism | ||
| Specific Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | ||
| Pathways | Not Available | ||
| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 18 | ||
| Locus | Not Available | ||
| SNPs | GOT2 | ||
| Gene Sequence |
>1293 bp ATGGCCCTGCTGCACTCTGGCCGCTTCCTGTCCGGAGTCGCCGCGGCTTTCCACCCAGGC CTCGCTGCCGCGGCTTCTGCCAGAGCCAGCTCCTGGTGGGCTCATGTGGAGATGGGGCCC CCAGATCCCATCCTGGGAGTAACAGAAGCCTTTAAGAGAGACACCAACAGCAAAAAGATG AACCTGGGAGTTGGTGCCTACCGGGATGATAATGGAAAGCCTTACGTGCTTCCAAGTGTC CGGAAGGCGGAGGCCCAGATTGCTGCAAAAAATTTGGATAAAGAATACCTGCCCATTGCG GGGCTGGCTGAATTTTGTAAGGCATCTGCAGAACTAGCCCTGGGTGAGAACAATGAAGTG TTGAAAAGTGGCCGGTATGTCACCGTGCAGACCATTTCTGGAACCGGGGCCTTAAGGATC GGAGCCAGTTTTCTGCAAAGATTTTTTAAGTTCAGCCGGGATGTCTTCCTGCCCAAACCA ACCTGGGGGAATCATACACCCATCTTCAGGGATGCTGGCATGCAGCTCCAGAGTTATCGG TACTATGACCCCAAGACGTGCGGCTTTGACTTCACAGGCGCTATTGAGGACATTTCAAAA ATACCAGCGCAGAGTGTCATTCTCCTGCACGCCTGTGCCCACAACCCCACGGGAGTGGAC CCTCGTCCTGAGCAGTGGAAGGAGATGGCGACAGTGGTGAAGAAAAACAATCTCTTTGCA TTCTTTGACATGGCCTACCAAGGCTTTGCCAGTGGCGATGGTAACAAGGATGCCTGGGCT GTGCGCCACTTCATCGAACAGGGCATTAATGTTTGTCTCTGCCAGTCCTATGCCAAGAAC ATGGGCTTATACGGTGAGCGTGTGGGAGCCTTCACTGTGGTCTGCAAAGATGCCGAGGAA GCCAAAAGAGTTGAGTCCCAGTTGAAGATCCTGATCCGTCCCATGTATTCCAACCCCCCT ATCAATGGGGCCCGGATTGCCTCCACTATTCTCACCAGCCCGGATTTGCGGAAACAATGG TTGCACGAAGTGAAGGGCATGGCCGACCGCATCATCAGCATGCGGACACAGCTGGTGTCC AACCTCAAGAAGGAGGGCTCCTCCCACAACTGGCAGCACATCATTGACCAGATCGGCATG TTTTGTTACACAGGCCTAAAGCCTGAACAGGTGGAGCGGCTGACCAAGGAGTTCTCCATC TACATGACAAAGGATGGCCGCATCTCTGTGGCAGGGGTCACCTCAGGCAACGTGGCATAC CTTGCTCACGCCATTCACCAGGTCACCAAGTAA |
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| Protein Properties | |||
| Number of Residues | 430 | ||
| Molecular Weight | 47514.0 | ||
| Theoretical pI | 9.45 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>Aspartate aminotransferase, mitochondrial MALLHSGRFLSGVAAAFHPGLAAAASARASSWWAHVEMGPPDPILGVTEAFKRDTNSKKM NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIAGLAEFCKASAELALGENNEV LKSGRYVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQSYR YYDPKTCGFDFTGAIEDISKIPAQSVILLHACAHNPTGVDPRPEQWKEMATVVKKNNLFA FFDMAYQGFASGDGNKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEE AKRVESQLKILIRPMYSNPPINGARIASTILTSPDLRKQWLHEVKGMADRIISMRTQLVS NLKKEGSSHNWQHIIDQIGMFCYTGLKPEQVERLTKEFSIYMTKDGRISVAGVTSGNVAY LAHAIHQVTK |
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| External Links | |||
| GenBank ID Protein | CAA80960.1 | ||
| UniProtKB/Swiss-Prot ID | P12344 | ||
| UniProtKB/Swiss-Prot Entry Name | AATM_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | Z25466 | ||
| GeneCard ID | GOT2 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||