Showing Protein Glutamyl aminopeptidase (BMDBP00572)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00572 |
| Secondary Accession Numbers | None |
| Name | Glutamyl aminopeptidase |
| Synonyms | Not Available |
| Gene Name | ENPEP |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Amino acid transport and metabolism |
| Specific Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 6 |
| Locus | Not Available |
| SNPs | ENPEP |
| Gene Sequence |
>2871 bp ATGATCTTGGAGGAGAGATCATCTTGGGAAGGCTCTAAGAGATACTGCATTAAGACGAAA CATGTGGCCATTATCTGCGCAGTGGTGGTGGCTGTCGGATTAATAGTAGGACTTTCTGTG GGTCTGACCAGATCATGTGACTCTACAGAGGGCATGACCCAGGGCACGACCCAGGGCACG ACCCAGGCTCCTTCCCACCTGCCTCCCGTTACCAGCCCTCCAGAGGACCAGGGGGTCTGC CCTGCCAGTGAGGATGAAAGCGGAGGCTGGAAAGACTTCAGGCTGCCGGACTTCATCAAA CCAGTGCACTACGACCTGGAGGTGAAGCCCCTGATGGAGCAGGACACGTACACGGGCAGC GTGGACATCTCCATCAACGTGAGCTCATCCACCCGGTACCTGTGGCTACATCTCCGGGAG ACGAGGATCACCAGGCTCCCGGTGCTGAGGAGGCCGTCTGGGGAGCAGGTTCAAGTCAGG CAGTGCTTCGAATACAAGAAGCAGGAGTATGTGGTGGTGGAAGCAGAAGAAGAGCTTGAG CCCAACACTGGCGAGGGTCCCTACCACCTGATCCTGGAGTTCGCCGGCTGGCTGAACGGC TCGCTCGTGGGATTTTACAGAACGACATACGTGGAGAAAGGACAAACCAAGAGCATAGCA GCCACTGATCATGAACCAACAGATGCCAGGAAATCCTTCCCTTGTTTTGATGAGCCCAAC AAAAAGGCAACGTATACAATATCCATTGTCCACTCCAAAGAATATAAGGCGCTTTCGAAT ATGCCAGTGGAGAAAGAAGAGTCAGTGGATGATATATGGAGTCGGACAACTTTCCAGAAG TCTGTTCCCATGAGTACTTACCTGGTGTGCTTTGCAGTGCATCAGTTTGACTCTGTAACG AGAATATCAAACAGGGGGATACCTCTCACTATATATGTCCAGCCAGAGCAAAAGCACACA GCTGAATATGCTGCAAACATAACTAAAAGTGTGTTTGACTATTTTGAAGACTACTTTGGT ATGAGTTATTCTCTTCCTAAATTAGATAAAATTGCTATTCCAGATTTCGGCACTGGGGCT ATGGAGAACTGGGGACTCATCACTTACAGAGAAACAAACCTGCTTTATGACCCTGATGAA TCTGCCTCATCAAACAAACAGAGGGTGGCTGCTGTGATAGCCCATGAGCTTGTGCATCAG TGGTTTGGAAATATTGTGACCATGGAATGGTGGGACGACTTGTGGCTAAATGAAGGATTT GCTTCCTTCTTTGAGTACCTGGGAGTAGCCTATGCAGAAAAAGACTGGCAAATGCGTGAT CAGATGATACTTGATGATGTATTACCTGTGCAAGAGGATGATTCTTTGATGTCTTCACAC CCAATAGTAGTCACTGTAGCAACTCCTGATGAAATAACATCTGTTTTTGATGGAATTTCC TATAGTAAGGGAGCTTCCATTCTGAGAATGCTTGAAAACTGGATAACACGAGAGAAATTT CAAATAGGATGTCAGAATTACTTGAAAAAACACAAATTTGAGAATGCCAAAACTTCAGAT TTCTGGGCAGCACTTGAAGAGGCAAGTAATCTCCCAGTGAAAGAAGTAATGGACACCTGG ACCAATCAGATGGGTTACCCTGTACTTAACGTGGACAATATGAAGAACATCACACAGAAA CGCTTTCTATTGGACCCGAGAGCTAATGCTTCTGAGCCACATTCAGCTTTTGGTTACACA TGGAATATTCCAATTAAATGGACTGAAGATGATGAACAAAGGATTACATTATACAATAGG TCAGAAACAGGAGGAATCACTTTGGAATCTACTCTTAGTGGGAATGCTTTTCTCAAAATA AACCCTGATCATATTGGCTTTTATCGTGTAAATTATGAAGTGTCAACTTGGGAATGGATA GCTACGAATCTTTCCGTCAACCACACGGACTTTTCTTCTGCTGATCGTGCAAGTTTTATT GATGATGCTTTTGCCTTGGCACGAGCTCAGCTTCTAAATTATAAGGAGGCTCTGAACTTG ACCAAGTATCTCAAGGAAGAAAAGGAATATTTACCATGGCACAGAGTCATTTCAGCTGTA ACCTATATTATTAGCATGTTTGAAGATGATAAAGAGCTATACCCTGTGATTGAGAAATAC TTCCGAGATCAAGTGAAGCCCATTGCAGATTCTCTGGGATGGAATGATGTTGGAGACCAC CTCACAAAATTACTCCGTGCGTCTGTATTAGGACTGGCGTGCAAGATGGGAGACAGCGAT GCCTTGAACAACGCTTCCCAGTTATTTCAGGAGTGGCTAACTGGGACTGTAAGTCTTCCT GTAAATCTCAGGCTTCTGGTATATCGGTATGGTATGCAGAACTCTGGCAATGAGACTTCA TGGAATTACACTCTCGAGCAATACCAGAAAACTTCATTAGCTCAAGAAAAAGAAAAGCTA CTGTATGGATTAGCATCAGTGAAGAATGTTACTCTTTTGTCAAGGTATTTGGATTTACTC AAGGACTCAAACCTTATTAAAACGCAGGATGTGTTTACAGTCATTCAGTACATCTCATAC AACAGCTATGGGAAGACTATGGCCTGGAATTGGATACAACTCAACTGGGAATATCTAGTC AACAGGTATACACTCAATAACAGAAACCTTGGCCGGATTGTCACTATAGCAGAGCCATTC AACACTGAACTACAACTCTGGCAGATCAAGAGCTTTTTCGAAAGATATCCTGAAGCTGGA GCGGGACAAAAACCTAGGGAGCAAGTACTGGAAACAGTGAAAAACAATATCGAGTGGCTA AAACAAAACAGGGACACCATAAGAAACTGGTTTCTTGATTTGAATGGTTAA |
| Protein Properties | |
| Number of Residues | 956 |
| Molecular Weight | 109801.0 |
| Theoretical pI | 4.92 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Glutamyl aminopeptidase MILEERSSWEGSKRYCIKTKHVAIICAVVVAVGLIVGLSVGLTRSCDSTEGMTQGTTQGT TQAPSHLPPVTSPPEDQGVCPASEDESGGWKDFRLPDFIKPVHYDLEVKPLMEQDTYTGS VDISINVSSSTRYLWLHLRETRITRLPVLRRPSGEQVQVRQCFEYKKQEYVVVEAEEELE PNTGEGPYHLILEFAGWLNGSLVGFYRTTYVEKGQTKSIAATDHEPTDARKSFPCFDEPN KKATYTISIVHSKEYKALSNMPVEKEESVDDIWSRTTFQKSVPMSTYLVCFAVHQFDSVT RISNRGIPLTIYVQPEQKHTAEYAANITKSVFDYFEDYFGMSYSLPKLDKIAIPDFGTGA MENWGLITYRETNLLYDPDESASSNKQRVAAVIAHELVHQWFGNIVTMEWWDDLWLNEGF ASFFEYLGVAYAEKDWQMRDQMILDDVLPVQEDDSLMSSHPIVVTVATPDEITSVFDGIS YSKGASILRMLENWITREKFQIGCQNYLKKHKFENAKTSDFWAALEEASNLPVKEVMDTW TNQMGYPVLNVDNMKNITQKRFLLDPRANASEPHSAFGYTWNIPIKWTEDDEQRITLYNR SETGGITLESTLSGNAFLKINPDHIGFYRVNYEVSTWEWIATNLSVNHTDFSSADRASFI DDAFALARAQLLNYKEALNLTKYLKEEKEYLPWHRVISAVTYIISMFEDDKELYPVIEKY FRDQVKPIADSLGWNDVGDHLTKLLRASVLGLACKMGDSDALNNASQLFQEWLTGTVSLP VNLRLLVYRYGMQNSGNETSWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLL KDSNLIKTQDVFTVIQYISYNSYGKTMAWNWIQLNWEYLVNRYTLNNRNLGRIVTIAEPF NTELQLWQIKSFFERYPEAGAGQKPREQVLETVKNNIEWLKQNRDTIRNWFLDLNG |
| External Links | |
| GenBank ID Protein | AAI09477.1 |
| UniProtKB/Swiss-Prot ID | Q32LQ0 |
| UniProtKB/Swiss-Prot Entry Name | AMPE_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC109476 |
| GeneCard ID | ENPEP |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |