| Identification |
|---|
| BMDB Protein ID
| BMDBP00594 |
| Secondary Accession Numbers
| None |
| Name
| L-xylulose reductase |
| Synonyms
|
Not Available
|
| Gene Name
| DCXR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 19 |
| Locus
| Not Available |
| SNPs
| DCXR |
| Gene Sequence
|
>735 bp
ATGGATTTGAGACTCGCGGGGCGCCGGGCGCTCGTCACGGGGGCGGGCAAAGGCATCGGT
CGCAGTATTGTCAAGGCGCTACACGCGGCTGGCGCCCGAGTGGTGGCCGTGAGCCGGACC
CAGGCCGACCTGGACAGCCTGGTCCGCGAGTGCCCCGGGGTAGAGACCGTGTGCGTGGAC
CTAGCTGACTGGGAGGCCACGGAGCAGGCGCTGGGAGGTGTTGGCCCTGTGGACCTGCTG
GTGAACAATGCAGCTGTGGCGTTTCTACAGCCCTTCCTGGAGGTCACCAAGGAGGCATAT
GACATGTCTTTCAGTGTGAACCTTCGGGCGGTCATCCAGGTGTCGCAGATTGTGGCCCGA
GGCCTGATAGCTCGGGGAGCCCCAGGGGTCATCGTGAATGTTTCTAGCCAGGCCTCCCAA
CGGGGACTGACTAACCACAGTGTCTACTGCTCCACTAAGGGTGCCTTGGACACACTGACC
AAAGTGATGGCTGTGGAGCTTGGGCCACACAAGATCCGTGTGAATGCAGTCAACCCCACG
GTGGTGATGACACCCATGGGCCAGGCCGCCTGGAGTGACCCTCAGAAGGCCAAGGCCATG
CTGGACCGCATCCCCCTTGGCAGGTTTGCCGAGGTGGAGAACGTGGTGGACACCATCCTC
TTCCTGCTCAGTGACCGCAGCAGCATGACCACAGGCTCCACTGTGCCAGTGGATGGGGGC
TTCCTGGCTACCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 244 |
| Molecular Weight
| 25650.0 |
| Theoretical pI
| 8.07 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>L-xylulose reductase
MDLRLAGRRALVTGAGKGIGRSIVKALHAAGARVVAVSRTQADLDSLVRECPGVETVCVD
LADWEATEQALGGVGPVDLLVNNAAVAFLQPFLEVTKEAYDMSFSVNLRAVIQVSQIVAR
GLIARGAPGVIVNVSSQASQRGLTNHSVYCSTKGALDTLTKVMAVELGPHKIRVNAVNPT
VVMTPMGQAAWSDPQKAKAMLDRIPLGRFAEVENVVDTILFLLSDRSSMTTGSTVPVDGG
FLAT
|
| External Links |
|---|
| GenBank ID Protein
| ABF57435.1 |
| UniProtKB/Swiss-Prot ID
| Q1JP75 |
| UniProtKB/Swiss-Prot Entry Name
| DCXR_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT025479 |
| GeneCard ID
| DCXR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
