| Identification |
|---|
| BMDB Protein ID
| BMDBP00597 |
| Secondary Accession Numbers
| None |
| Name
| Dihydropteridine reductase |
| Synonyms
|
Not Available
|
| Gene Name
| QDPR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases. |
| Pathways
|
|
| Reactions
|
| Tetrahydrobiopterin + NADP → Dihydrobiopterin + NADPH |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| Not Available |
| SNPs
| QDPR |
| Gene Sequence
|
>729 bp
ATGGCGGCGGCCGCGGGCGAGGCGCGCCGGGTGCTGGTGTACGGCGGCCGGGGCGCGCTG
GGCTCGCGATGCGTGCAGGCCTTCCGGGCCCGCAACTGGTGGGTTGCCAGCATCGACGTG
CAGGAGAACGAAGAGGCCAGTGCCAACGTCGTGGTTAAAATGACGGACTCGTTCACGGAG
CAGGCCGACCAGGTGACAGCTGAGGTGGGGAAGCTCCTGGGCACAGAGAAGGTGGACGCG
ATCCTTTGTGTGGCTGGAGGATGGGCCGGGGGCAATGCCAAGTCCAAGTCGCTCTTTAAA
AACTGTGACCTGATGTGGAAGCAGAGCGTGTGGACATCCACCATCTCCAGCCACCTGGCC
ACCAAGCACCTCAAGGAAGGAGGCCTCCTGACCTTGGCAGGGGCCAGGGCCGCCCTGGAC
GGGACGCCCGGGATGATCGGCTACGGCATGGCCAAGGCCGCGGTTCACCAGCTCTGCCAG
AGCCTGGCCGGGAAGAGCAGTGGCCTGCCGCCCGGGGCTGCAGCCGTCGCCCTGCTCCCG
GTCACCCTGGACACCCCGGTGAACAGGAAGTCAATGCCCGAAGCCGACTTCAGCTCCTGG
ACGCCCTTGGAGTTCCTGGTCGAAACCTTCCATGACTGGATCACAGAGAAGAATCGACCA
AGCTCAGGAAGCCTAATCCAGGTGGTGACCACGGAGGGGAAGACAGAGCTTACCGCAGCA
TCTCCATAA
|
| Protein Properties |
|---|
| Number of Residues
| 242 |
| Molecular Weight
| 25504.0 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dihydropteridine reductase
MAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVQENEEASANVVVKMTDSFTE
QADQVTAEVGKLLGTEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSVWTSTISSHLA
TKHLKEGGLLTLAGARAALDGTPGMIGYGMAKAAVHQLCQSLAGKSSGLPPGAAAVALLP
VTLDTPVNRKSMPEADFSSWTPLEFLVETFHDWITEKNRPSSGSLIQVVTTEGKTELTAA
SP
|
| External Links |
|---|
| GenBank ID Protein
| AAI02194.1 |
| UniProtKB/Swiss-Prot ID
| Q3T0Z7 |
| UniProtKB/Swiss-Prot Entry Name
| DHPR_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC102193 |
| GeneCard ID
| QDPR |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
