Showing Protein Leukotriene A-4 hydrolase (BMDBP00610)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00610 | ||
| Secondary Accession Numbers | None | ||
| Name | Leukotriene A-4 hydrolase | ||
| Synonyms | Not Available | ||
| Gene Name | LTA4H | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Amino acid transport and metabolism | ||
| Specific Function | Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity (By similarity). | ||
| Pathways |
|
||
| Reactions |
|
||
| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 5 | ||
| Locus | Not Available | ||
| SNPs | LTA4H | ||
| Gene Sequence |
>1836 bp ATGCCCGAGGTAGTGGATACGTGCTCCTTGGCCTCCCCGGCGTCCGTCTGCCAGACCAAA CACCTGCACCTGCGTTGCAGCATCGACTTTACTCGCCGGGTACTGAGCGGGACCGCCGCG CTCACCATCCAGTCCCAGGAGGACAATCTGCGCAGCCTGATTCTGGATACAAAGGACCTC ACAATAGAAAAAGTGGTCATCAATGGACAAGAAGTCAAATATACTCTTGGAGAAAGACAA AGTTACAAAGGATCACCAATCGAAATCTCTCTTCCTATTGCTCTATGCAAAAATCAAGAA ATTGTTATAGAGATTTCTTTCGAGACATCTCCAAAATCTTCTGCTCTTCAGTGGCTCACT CCTGAACAAACTTCTGGGAAAGAGCACCCCTATCTCTTTAGTCAGTGCCAGGCTATCCAC TGTAGAGCTATTCTTCCTTGCCAGGACACTCCTTCCGTGAAATTAACCTACAGCGCAGAG GTGTCTGTCCCCAAAGAACTGGTGGCACTTATGAGTGCCATTCGTGACGGAGAAGCACCT GACCCAGAAGACCCGAACAGGAAAATTTACAGATTCAGCCAAAAAGTTCCAATCCCCTGC TACCTGATTGCTTTGGTTGTTGGAGCTTTAGAAAGCAGACAGATTGGCCCAAGGACATTG GTATGGTCCGAGAAAGAGCAGGTGGAAAAGTCTGCTTACGAATTTTCTGAGACTGAATCT ATGCTTAAAATTGCAGAAGATCTGGGAGGCCCATATATTTGGGGGCAGTATGACCTATTG GTCCTGCCGCCATCCTTTCCCTATGGCGGCATGGAGAACCCTTGCCTCACTTTTGTAACT CCTACTCTGCTGGCTGGTGACAAGTCACTCTCCAATGTTATAGCACATGAAATATCTCAT AGTTGGACAGGAAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAAGGA CATACCGTATACTTGGAACGCCACATTTGTGGACGACTGTTTGGTGAAAAGTTTAGACAT TTTCACGCTCTGGGCGGATGGGGAGAACTCCAGAATTCGATAAAGACTTTTGGGGAGACC CATCCTTTCACCAAACTCGTGGTTGACCTGACGAACACAGACCCTGACGTGGCATATTCT TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTCTTTTACCTTGAACAGCTTCTTGGAGGA CCAGAGGTTTTCCTAGGATTCTTAAAGGCTTATGTTGAGAAATTTTCCTACAAGAGCATA ACTACTGATAACTGGAAGGATTTCTTGTATTCCCACTTTAAAGATAAGGTTGATATTCTC AATCAAGTGGATTGGAACACCTGGCTGTACTCTCCTGGACTGCCCCCTGTAAAACCCAAT TATGATATGACCCTGACAAATGCTTGCATTTCCTTGAGTCAAAGATGGATCACTGCCAAA GATGATGATTTAAATTCATTCAGCTCAGCAGACCTAAAAGACTTCTCTTCCCATCAAGTG AATGAATTTTTAGCACAGATGCTCCAGAATGCACCTCTTCCATTGGGGCACATAAAGCGA ATGCAAGAGGTGTACAACTTCAATGCCATTAACAATTCTGAAATACGATTCAGATGGTTA CGACTCTGCATTCAATCGAAATGGGAGGAAGCAATTCCTTTGGCTCTAAAAATGGCAACT GAACAAGGAAGGATGAAGTTTACACGGCCCTTATTCAAGGACCTTGCTGCCTTTGACAAA TCCCATGATCAAGCCATCCGTACCTACAAGGAGCACAAGGCATCCATGCACCCTGTGACT GCCATGCTTGTGGGGAAAGATTTAAAAGTGGATTAA |
||
| Protein Properties | |||
| Number of Residues | 611 | ||
| Molecular Weight | 69306.0 | ||
| Theoretical pI | 6.33 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
|
||
| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>Leukotriene A-4 hydrolase MPEVVDTCSLASPASVCQTKHLHLRCSIDFTRRVLSGTAALTIQSQEDNLRSLILDTKDL TIEKVVINGQEVKYTLGERQSYKGSPIEISLPIALCKNQEIVIEISFETSPKSSALQWLT PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYSAEVSVPKELVALMSAIRDGEAP DPEDPNRKIYRFSQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES MLKIAEDLGGPYIWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFHALGGWGELQNSIKTFGET HPFTKLVVDLTNTDPDVAYSSVPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYKSI TTDNWKDFLYSHFKDKVDILNQVDWNTWLYSPGLPPVKPNYDMTLTNACISLSQRWITAK DDDLNSFSSADLKDFSSHQVNEFLAQMLQNAPLPLGHIKRMQEVYNFNAINNSEIRFRWL RLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAIRTYKEHKASMHPVT AMLVGKDLKVD |
||
| External Links | |||
| GenBank ID Protein | AAI02853.1 | ||
| UniProtKB/Swiss-Prot ID | Q3SZH7 | ||
| UniProtKB/Swiss-Prot Entry Name | LKHA4_BOVIN | ||
| PDB IDs | |||
| GenBank Gene ID | BC102852 | ||
| GeneCard ID | LTA4H | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||