Showing Protein N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (BMDBP00612)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00612 |
| Secondary Accession Numbers | None |
| Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| Synonyms | Not Available |
| Gene Name | DDAH1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Amino acid transport and metabolism |
| Specific Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | DDAH1 |
| Gene Sequence |
>858 bp ATGGCTTCTCTCGGCCACCCAGCCACCTTTGGCCGGGCCACCCATGTCGTGGTACGGGCG CTGCCCGAGTCCCTCGCCCAACAGGCGCTGAGGCGCACCAAGGGCGACGAGGTGGATTTC GCCCGCGCTGAGCGGCAGCACCAGCTCTACGTGGGCGTGCTGGGCAGTAAACTGGGGCTG CAGGTGGTGCAGCTGCCCGCCGACGAGAGCCTCCCAGACTGCGTGTTCGTGGAGGACGTG GCCGTGGTGTGCGAGGAGACGGCCCTGATCACCCGCCCCGGGGCGCCGAGCCGGAGGAAG GAGGCTGACATGATGAAAGAAGCACTAGAAAAACTTCAGCTCAACATAGTAGAGATGAAA GATGAAAATGCAACTTTAGATGGTGGAGATGTCTTATTCACAGGCAGAGAATTTTTTGTG GGCCTTTCCAAAAGGACAAATCAACGAGGTGCGGAAATCTTGGCTGATACTTTTAAGGAC TATGCGGTCTCCACGGTCCCTGTGGTGGATGCTTTGCACTTGAAGAGTTTCTGCAGCATG GCTGGGCCTAACCTAATCGCTATTGGATCCAGTGAATCTGCACAGAAGGCCCTCAAGATC ATGCAACAGATGAGTGATCATCGCTACGACAAACTCACAGTGCCTGATGACACGGCCGCA AACTGCATATACCTGAATATCCCCAGCAAAGGCCACGTCTTGCTGCACCGAACCCCAGAA GAGTACCCAGAGAGTGCAAAGGTTTATGAAAAGCTGAAGGACCATATGCTGATCCCCGTG AGCAATTCTGAACTGGAAAAGGTGGACGGGCTGCTCACCTGCAGCTCGGTTTTAATTAAC AAGAAAGTAGACTCCTGA |
| Protein Properties | |
| Number of Residues | 285 |
| Molecular Weight | 31289.0 |
| Theoretical pI | 5.88 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 MASLGHPATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGL QVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMK DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSM AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPE EYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINKKVDS |
| External Links | |
| GenBank ID Protein | AAI49999.1 |
| UniProtKB/Swiss-Prot ID | P56965 |
| UniProtKB/Swiss-Prot Entry Name | DDAH1_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC149998 |
| GeneCard ID | DDAH1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |