Showing Protein Pyruvate carboxylase, mitochondrial (BMDBP00615)
| Identification | |||||||||
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| BMDB Protein ID | BMDBP00615 | ||||||||
| Secondary Accession Numbers |
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| Name | Pyruvate carboxylase, mitochondrial | ||||||||
| Synonyms | Not Available | ||||||||
| Gene Name | PC | ||||||||
| Protein Type | Enzyme | ||||||||
| Biological Properties | |||||||||
| General Function | Involved in ATP binding | ||||||||
| Specific Function | Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (By similarity). | ||||||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||||||
| Cellular Location | Not Available | ||||||||
| Gene Properties | |||||||||
| Chromosome Location | 29 | ||||||||
| Locus | Not Available | ||||||||
| SNPs | PC | ||||||||
| Gene Sequence |
>3537 bp ATGCTGAAGTTTCAGACTGTCCGGGGGAGCCTGAGGCTCCTGGCTATCCGCCGGACCTCC ACCGCAACCGCTGCCTCTCCCAATGTCCGGCGCCTGGAGTACAAGCCCATCAAGAAGGTC ATGGTGGCCAACAGAGGCGAGATCGCCATCCGTGTGTTCCGGGCCTGCACGGAGCTGGGC ATCCGCACGGTGGCTGTCTACTCGGAGCAGGACACGGGCCAAATGCACCGACAGAAAGCT GACGAAGCCTACCTCATCGGCCGGGGTCTTGCCCCGGTGCAGGCCTATCTGCACATTCCA GACATCATTAAGGTCGCCAAGGAGAACAACGTGGACGCTGTGCACCCGGGCTACGGGTTC CTGTCGGAGCGGGCCGACTTTGCCCAGGCCTGCCAGGATGCTGGGGTCCGGTTCATTGGG CCAAGCCCCGAGGTGGTCCGCAAGATAGGTGACAAGGTGGAGGCCCGGACCATCGCCATC GCCGCAGATGTGCCCGTGGTGCCCGGCACGAATGCCCCCATCACTTCCCTGCACGAGGCC CACGAGTTCTCCAACACCTACGGCTTCCCCATCATCTTCAAGGCCGCCTACGGGGGCGGG GGCCGCGGCATGAGGGTCGTGCACAGCTACGAGGAGCTGGAGGAGAACTACACCCGGGCC TACTCGGAGGCTCTGGCCGCCTTCGGGAACGGGGCGCTGTTCGTGGAGAAGTTCATCGAG AAGCCACGCCACATCGAGGTGCAGATCCTGGGGGACCAGTACGGGAACATCCTTCACCTC TACGAGCGGGACTGCTCCATCCAGCGGCGGCACCAGAAAGTGGTGGAGATCGCCCCGGCT GCCCACTTGGACCCCCAGCTGCGCACCCGGCTCACTAGCGACTCCGTCAAGCTTGCAAAG CAGGTGGGCTACGAGAACGCGGGCACCGTGGAGTTCCTGGTGGACAGGCACGGCAAGCAC TACTTCATCGAGGTCAACTCGCGCCTGCAGGTGGAGCACACGGTGACCGAGGAGATCACA GATGTGGACCTGGTCCACGCCCAGATCCACGTGGCCGAGGGCCGGAGCCTGCCTGACCTG GGCCTCCGGCAGGAGAACATCCGCATCAACGGCTGTGCCATCCAGTGCCGGGTTACCACC GAGGACCCTGCGCGCAGCTTCCAGCCCGACACCGGCCGCATCGAGGTGTTCCGGAGCGGG GAGGGCATGGGCATCCGCCTGGACAACGCCTCTGCCTTCCAAGGCGCCGTCATCTCCCCC CACTACGACTCCCTGCTGGTCAAGGTCATCGCTCACGGCAAGGACCACCCCACGGACGCC ACCAAGATGAGCAGAGCCCTGGCCGAGTTCCGAGTCCGAGGCGTGAAGACCAACATCCCC TTCCTGCAGAACGTGCTCAACAACCAGCAGTTCCTGGCAGGCACCGTGGACACGCAGTTC ATCGACGAGAACCCAGAGCTGTTCCAGCTGCGGCCCGCACAGAACCGGGCCCAGAAGCTG CTGCACTACCTCGGACACGTCATGGTGAATGGCCCAACTACTCCGATCCCCGTCAAGGCC AGCCCCAGCCCCACGGACCCCATCGTCCCTGTGGTGCCCATAGGCCCACCCCCAACGGGT TTCAGAGACATCCTGCTACGGGAGGGGCCCGAGGGCTTTGCTCGAGCGGTGCGGAACCAT GAGGGGCTGCTGCTGATGGACACGACCTTCAGGGACGCCCACCAGTCACTGCTGGCCACT CGAGTGCGCACCCACGATCTCAAAAAGATCTCCCCCTATGTTGCCCACAGCTTCAACAAA CTCTTCAGCATAGAGAACTGGGGAGGAGCCACCTTTGACGTCGCCATGCGCTTCCTGTAC GAGTGCCCCTGGCGACGGCTGCAGGAGCTCCGGGAGCTCGTCCCCAACATCCCATTCCAG ATGCTGCTGCGGGGGGCCAACGCCGTGGGCTACACCAACTACCCCGACAATGTGGTCTTC AAGTTCTGCGAGGTGGCCAAGGAGAATGGCATGGACATCTTCCGGGTCTTTGACTCCCTC AACTACCTGCCCAACCTGCTGCTGGGCATGGAGGCGGCGGGCAGTGCTGGTGGCGTGGTG GAGGCCGCCATCTCCTACACGGGTGACGTGTCCGACCCCAGCCGCACCAAGTACTCGCTG CAGTACTACATGGGCTTGGCCGAGGAGCTGGTGCGAGCCGGCACCCACATCCTGTGCATC AAGGACATGGCTGGGCTGCTGAAGCCTACGGCCTGCACCATGCTGGTCAGCTCCCTCCGG GACCGCTTCCCTGACCTCCCGCTGCACATCCACACCCACGACACGTCAGGGGCGGGCGTG GCAGCCATGCTGGCCTGTGCTCACGCAGGGGCTGACGTGGTGGATGTGGCGGCTGACTCC ATGTCTGGAATGACATCACAGCCCAGCATGGGGGCCCTGGTGGCCTGTACCCGAGGGACG CCCCTGGACACAGGCGTGCCCCTGGAGCGTGTGTTCGACTACAGCGAGTACTGGGAGGGG GCCCGGGGGCTGTACGCGGCCTTTGACTGCACGGCCACCATGAAGTCTGGCAACTCGGAC GTGTATGAGAACGAGATCCCAGGGGGCCAGTACACCAACCTGCACTTCCAGGCGCACAGC ATGGGGCTCGGCTCCAAGTTCAAGGAGGTCAAGAAGGCCTACGTGGAGGCCAACCAGATG CTGGGCGACCTCATCAAGGTGACGCCCTCCTCCAAGATCGTGGGGGACCTGGCCCAGTTC ATGGTGCAGAACGGGCTGACCCGAGCTGAGGCCGAAGCGCAGGCAGAGGAGCTGTCCTTC CCCCGCTCGGTGGTGGAGTTCCTGCAGGGCTACATCGGCATCCCCCACGGGGGCTTCCCA GAGCCCCTTCGCTCCAAGGTGCTGAAAGACCTGCCGAGGGTGGAGGGCCGGCCAGGAGCC TCCCTCCCACCCCTGGACCTGCAGGCGCTGGAGAAGGAGCTGACGGAACGGCACGGGGAG GAGGTGACCCCGGAGGACGTGCTCTCAGCCGCCATGTACCCCGACGTCTTTGCCCACTTC AAGGACTTCACTGCCACCTTCGGCCCCCTGGACAGCCTCAATACGCGCCTCTTCCTGCAG GGACCCAAGATTGCAGAGGAGTTTGAGGTGGAGCTGGAGCGAGGCAAGACGCTGCACATC AAAGCCTTGGCCATAAGTGACCTCAACCGGGCGGGCCAGAGGCAGGTCTTCTTCGAGCTC AACGGACAGCTGCGGTCCATCCTGGTCAAGGACACCCAGGCCATGAAGGAGATGCACTTC CACCCCAAGGCCCTGAAGGACGTCAAGGGCCAGATTGGGGCACCCATGCCCGGGAAGGTG ATAGACATCAAGGTGGCAGCAGGGGCCAAGGTGACCAAGGGCCAACCCCTGTGTGTGCTC AGCGCCATGAAGATGGAGACTGTAGTGACCTCGCCCGTGGAGGGCACTGTCCGCAAGGTC CACGTGACTAAGGACATGACGCTGGAGGGTGACGACCTCATCCTGGAGATCGAGTGA |
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| Protein Properties | |||||||||
| Number of Residues | 1178 | ||||||||
| Molecular Weight | 129698.0 | ||||||||
| Theoretical pI | 6.83 | ||||||||
| Pfam Domain Function | Not Available | ||||||||
| Signals |
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| Transmembrane Regions | Not Available | ||||||||
| Protein Sequence |
>Pyruvate carboxylase, mitochondrial MLKFQTVRGSLRLLAIRRTSTATAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG IRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQF IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPIVPVVPIGPPPTG FRDILLREGPEGFARAVRNHEGLLLMDTTFRDAHQSLLATRVRTHDLKKISPYVAHSFNK LFSIENWGGATFDVAMRFLYECPWRRLQELRELVPNIPFQMLLRGANAVGYTNYPDNVVF KFCEVAKENGMDIFRVFDSLNYLPNLLLGMEAAGSAGGVVEAAISYTGDVSDPSRTKYSL QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV AAMLACAHAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTGVPLERVFDYSEYWEG ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM LGDLIKVTPSSKIVGDLAQFMVQNGLTRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFP EPLRSKVLKDLPRVEGRPGASLPPLDLQALEKELTERHGEEVTPEDVLSAAMYPDVFAHF KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAISDLNRAGQRQVFFEL NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVAAGAKVTKGQPLCVL SAMKMETVVTSPVEGTVRKVHVTKDMTLEGDDLILEIE |
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| External Links | |||||||||
| GenBank ID Protein | AAO27903.1 | ||||||||
| UniProtKB/Swiss-Prot ID | Q29RK2 | ||||||||
| UniProtKB/Swiss-Prot Entry Name | PYC_BOVIN | ||||||||
| PDB IDs | Not Available | ||||||||
| GenBank Gene ID | AY185595 | ||||||||
| GeneCard ID | PC | ||||||||
| GenAtlas ID | Not Available | ||||||||
| HGNC ID | Not Available | ||||||||
| References | |||||||||
| General References | Not Available | ||||||||