Showing Protein Trimethyllysine dioxygenase, mitochondrial (BMDBP00622)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 8 metabolites
Identification
BMDB Protein ID BMDBP00622
Secondary Accession Numbers None
Name Trimethyllysine dioxygenase, mitochondrial
Synonyms Not Available
Gene Name TMLHE
Protein Type Enzyme
Biological Properties
General Function Secondary metabolites biosynthesis, transport and catabolism
Specific Function Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Pathways
  • Amine and polyamine biosynthesis
  • Carnitine biosynthesis
  • Carnitine Synthesis
Reactions
N6,N6,N6-Trimethyl-L-lysine + Oxoglutaric acid + Oxygen → 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinic acid + Carbon dioxide details
3-Dehydroxycarnitine + Oxoglutaric acid + Oxygen → L-Carnitine + Succinic acid + Carbon dioxide details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location X
Locus Not Available
SNPs TMLHE
Gene Sequence 
>1266 bp
ATGTGGTGTCACAGGTTGTCCCACCTACAAAGCAGGCTCCAGGACCTGCTGAGGGGACGG
GTCACACGTTGGGCCCTTCAACAGTCCAACTTCAAAAGCTTATTTCCACTAGCCATCTAT
TGGCACCATACAGCCTCCAAGTCTCTGAATTGTGTTTGGCAGCAACATGAAGATCATTTT
GAACTGCAATATGCTAACAATGTGATGCGCTTTGATTATGTCTGGCTTCGAGACCACTGC
CGCTCAGCATCTTGCTACAACTCTAAGACTCACCAGCGCAGCCTAGACACTGCCAGCGTG
GATTTATGTATCCAGCCACAGACCATTCATCTGGATGAGACCACACTCTTTTTCACTTGG
CCAGATGGTCATGTGACTAGATATGATTTGGATTGGCTCATGAAAAACAGCTATGAAGGG
CAGAAACAAAAGGTCATCCAGCCTAGAATCTTATGGAATGCTGAAATCTACCAGCAAGCC
CAAGTTCCAGCTGTAGATTTCCAGACGTTCTTAGAAACCAAGGAGGGACTGAAGAACTTT
CTGCAGAACTTTCTGCTCTATGGAATTGCTTTTGTGGAAAATGTCCCTCCTACTCAGAAA
CACACAGAGAAGCTGGCAGAAAGGATCAGCTTGATCAGAGAAACCATCTATGGAAGGATG
TGGTTTTTCACTTCAGACTTCTCCAGAGGTGACACTGCATACACCAAGCTAGCTCTGGAT
CGGCACACTGACACCACCTATTTTCAAGAGCCCTGTGGCATTCAAGTGTTTCACTGTCTT
AAGCATGAAGGAACAGGTGGCAGGACACTGCTAGTTGATGGATTCTATGCAGCAGAACAA
GTACTTCAAAAGGCACCTGAGGAATTTGAACTCCTCAGTAAAGTGCCATTGAAGCATGAA
TATATTGAAAATGTTGGAGAATGTCAAAACCACATGATTGGGGTTGGGCCAGTCTTAAAT
ATCTACCCATGGAATAAAGAGCTCTATTTGATCAGGTACAACAACTATGACCGGGCTGTC
ATAAATACTGTACCTTATGATGTTGTCCATCGTTGGTATACAGCACACCGGACTCTAACC
AGAGAGTTGAGGAGGCCTGAGAATGAGTTTTGGGTCAAACTCAAGCCTGGCAAGGTACTA
TTTATAGACAACTGGCGTGTCCTACATGGCAGGGAATCCTTCACAGGCTACCGCCAACTC
TGTGGCTGCTATTTAACAAGGGATGATGTATTAAACACTGCTCGTCTCTTGGGCCTTCAG
GCTTAA
Protein Properties
Number of Residues 421
Molecular Weight 49837.0
Theoretical pI 7.97
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>Trimethyllysine dioxygenase, mitochondrial
MWCHRLSHLQSRLQDLLRGRVTRWALQQSNFKSLFPLAIYWHHTASKSLNCVWQQHEDHF
ELQYANNVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIQPQTIHLDETTLFFTW
PDGHVTRYDLDWLMKNSYEGQKQKVIQPRILWNAEIYQQAQVPAVDFQTFLETKEGLKNF
LQNFLLYGIAFVENVPPTQKHTEKLAERISLIRETIYGRMWFFTSDFSRGDTAYTKLALD
RHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHE
YIENVGECQNHMIGVGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLT
RELRRPENEFWVKLKPGKVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARLLGLQ
A
GenBank ID Protein AAI20319.1
UniProtKB/Swiss-Prot ID Q0VC74
UniProtKB/Swiss-Prot Entry Name TMLH_BOVIN
PDB IDs Not Available
GenBank Gene ID BC120318
GeneCard ID TMLHE
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available