Showing Protein Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (BMDBP00625)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00625 |
| Secondary Accession Numbers | None |
| Name | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial |
| Synonyms | Not Available |
| Gene Name | SUCLA2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Energy production and conversion |
| Specific Function | ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. |
| Pathways |
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| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 12 |
| Locus | Not Available |
| SNPs | SUCLA2 |
| Gene Sequence |
>1392 bp ATGGCGGCCTCCGTGTTCTACAGCCGGCTCTTGGCTGCCGCCACCCTGAGGAGCCACCGA CCCCGAACGGCGCTGCCGGCCGCCGCCCAGGTCCTGGGAAGCTCTGGATTGTTTAACAAC CATGGAGTCCAAATACAGCATCAACAGCAAAGGAATCTCTCGCTGCATGAATACCTGAGT ATGGAATTGTTGCAGGAAGCTGGCGTCTCCATTCCCAAAGGACATGTGGCTAAGTCACCA GATGAAGCTTATGCGATTGCCAAAAAATTAGGTTCAAAAGATGTTGTGATAAAGGCGCAA GTTTTGGCTGGTGGCAGAGGAAAAGGAACATTTGAAAGTGGCCTCAAAGGAGGAGTGAAG ATAGTTTTCTCTCCAGAAGAAGCAAAAGCTGTTTCCTCACAAATGATTGGGAAAAAGTTG TTTACCAAGCAAACAGGAGAAAAGGGCAGGATATGCAATCAAGTATTGGTTTGTGAACGA AGATATCCCAGGAGAGAATACTACTTTGCAATCACAATGGAAAGGTCATTTCAAGGTCCT GTATTAATAGGAAGTTCTCACGGTGGTGTCAACATTGAAGATGTTGCTGCTGAGACTCCC GAGGCCATAGTTAAAGAGCCTATCGATATCGTAGAAGGCATCAAAAAGGAACAAGCTGTC CGGCTTGCACAGAAGATGGGATTTCCAGCCAGTATTGTGGATTCTGCAGCAGAAAACATG ATCAAGCTTTATGACCCTTTTCTGAAATACGATGCAACCATGGTAGAAATAAATCCAATG GTAGAGGATTCAGATGGAGCTGTGCTGTGTATGGATGCAAAGATCAATTTTGATTCTAAT TCAGCTTATCGTCAGAAGAAAATCTTTGACCTGCAGGACTGGACCCAGGAAGATGAAAGG GACAAAGATGCAGCTAAGGCAGATCTCAACTACATTGGCCTTGACGGAAATATCGGCTGT CTAGTGAATGGTGCTGGTTTGGCTATGGCTACAATGGATATAATAAAACTCCATGGAGGG ACTCCAGCCAACTTTCTTGATGTTGGTGGTGGTGCCACAGTCCATCAAGTAACAGAAGCG TTTAAACTTATCACTTCAGATAAAAAGGTACTATCTATTTTGGTCAACATTTTTGGAGGA ATCATGCGGTGTGACGTTATTGCACAGGGTATAGTCATGGCAGTAAAGGATTTGGAAATT AAAATACCTATTGTGGTACGGTTACAAGGTACACGAGTTGATGATGCTAAGGCACTGATA GCGGACAGTGGACTTAAAATCCTTGCTTGTGATGACTTGGATGAAGCTGCTAAAATGGTT GTAAAGCTCTCTGAGATAGTGACCTTAGCCAAGCAAGCCCAGGTGGATGTGAAATTTCAG TTGCCAATCTGA |
| Protein Properties | |
| Number of Residues | 463 |
| Molecular Weight | 50130.0 |
| Theoretical pI | 7.21 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial MAASVFYSRLLAAATLRSHRPRTALPAAAQVLGSSGLFNNHGVQIQHQQQRNLSLHEYLS MELLQEAGVSIPKGHVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERRYPRREYYFAITMERSFQGP VLIGSSHGGVNIEDVAAETPEAIVKEPIDIVEGIKKEQAVRLAQKMGFPASIVDSAAENM IKLYDPFLKYDATMVEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER DKDAAKADLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA FKLITSDKKVLSILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPIVVRLQGTRVDDAKALI ADSGLKILACDDLDEAAKMVVKLSEIVTLAKQAQVDVKFQLPI |
| External Links | |
| GenBank ID Protein | AAI18444.1 |
| UniProtKB/Swiss-Prot ID | Q148D5 |
| UniProtKB/Swiss-Prot Entry Name | SUCB1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC118443 |
| GeneCard ID | SUCLA2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |