Showing Protein Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (BMDBP00628)
| Identification | |||
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| BMDB Protein ID | BMDBP00628 | ||
| Secondary Accession Numbers |
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| Name | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | ||
| Synonyms | Not Available | ||
| Gene Name | DLST | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Energy production and conversion | ||
| Specific Function | Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity). | ||
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 10 | ||
| Locus | Not Available | ||
| SNPs | DLST | ||
| Gene Sequence |
>1368 bp ATGCTGTCCCGGTCCCGCTGCGCGTCCCGGGCGTTCAGCCGCTCGCTGTCCGCCTTCCAG AAGGGGAACTGCCCTCTAGTGAGACGTTCCCTGCCTGGGATCTCCTTATGTCAGGGACCA GGTTACCCTGACAGCAGGAAGACTGTCATTAACAGCAGTAATATCTTCAGCGTTCGCTTC TTTAGAACTACAGCTGTGTGCAAGGATGATGTGATTACAGTCAAAACCCCAGCATTTGCA GAATCTGTCACAGAGGGGGATGTCAGGTGGGAGAAAGCTGTTGGAGACACAGTTGCAGAA GATGAAGTGGTTTGTGAGATTGAAACTGACAAGACCTCTGTGCAGGTTCCGTCACCAGCA AATGGCGTGATTGAAGCTCTTTTGGTACCTGATGGGGGAAAAGTAGAAGGAGGCACTCCT CTTTTCACACTCAGGAAAACTGGCGCTGCTCCTGCTAAGGCCAAGCCAGCTGCAGCCCCT GCTGCCGCAGCCCCAAAAGCAGAACCCACAGTGTCTGCTGTTCCTCCTCCCCCTGCAGCA CCTATACCCACCCAGATGCCACCTGTGCCCTCGCCCTCACAGCCGCTCACTAGCAAACCA GTGTCTGCTGTAAAACCCACCGCTGCCCCTCCAAGAGCTGAGGCAGGAGCTGGTGTAGGT CTGCGTTCAGAACATCGGGAGAAGATGAACAGGATGCGGCAACGCATCGCCCAGCGTCTG AAGGAGGCTCAGAACACCTGCGCGATGCTCACCACTTTCAATGAGATTGACATGAGTAAT ATCCAGGAGATGCGGGCTCGGCACAAAGATGCTTTTCTGAAGAAACATAACCTCAAACTA GGCTTCATGTCAGCATTTGTGAAGGCCTCAGCCTTTGCCTTGCAGGAGCAGCCTGTGGTA AATGCAGTGATTGACGATGCAACCAAAGAGGTGGTGTATAGGGATTATATTGACATCAGC GTTGCGGTGGCCACCCCTCGGGGTCTGGTTGTTCCCGTCATCAGGAATGTGGAAACAATG AATTATGCCGATATTGAGCGAACCATCAGTGAACTGGGAGAGAAGGCCCGGAAGAATGAA CTTGCCATTGAAGATATGGATGGTGGTACTTTTACCATCAGCAATGGAGGTGTTTTTGGC TCGCTCTTTGGAACACCCATCATCAACCCCCCTCAGTCTGCCATCCTGGGCATGCATGCC ATCGTTGATAGGCCAGTGGTCATAGGAGGCAAGGTGGAGGTGCGGCCCATGATGTACGTG GCCCTGACGTATGATCACCGGCTGATCGATGGCAGAGAGGCTGTGACTTTCCTCCGCAAA ATTAAGGCAGCGGTAGAGGATCCCAGAGTCCTCCTACTGGACCTTTAG |
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| Protein Properties | |||
| Number of Residues | 455 | ||
| Molecular Weight | 48973.0 | ||
| Theoretical pI | 9.36 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial MLSRSRCASRAFSRSLSAFQKGNCPLVRRSLPGISLCQGPGYPDSRKTVINSSNIFSVRF FRTTAVCKDDVITVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPA NGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAAAPAAAAPKAEPTVSAVPPPPAA PIPTQMPPVPSPSQPLTSKPVSAVKPTAAPPRAEAGAGVGLRSEHREKMNRMRQRIAQRL KEAQNTCAMLTTFNEIDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVV NAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTISELGEKARKNE LAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIVDRPVVIGGKVEVRPMMYV ALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL |
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| External Links | |||
| GenBank ID Protein | ABG67046.1 | ||
| UniProtKB/Swiss-Prot ID | P11179 | ||
| UniProtKB/Swiss-Prot Entry Name | ODO2_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | BT026207 | ||
| GeneCard ID | DLST | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||