| Identification |
|---|
| BMDB Protein ID
| BMDBP00629 |
| Secondary Accession Numbers
| None |
| Name
| 5-aminolevulinate synthase, erythroid-specific, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| ALAS2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| Not Available |
| Pathways
|
- 5-aminolevulinate from glycine: step 1/1
- Porphyrin-containing compound metabolism
- Protoporphyrin-IX biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Not Available |
| SNPs
| ALAS2 |
| Gene Sequence
|
>1764 bp
ATGGTGACAGCAGCCATGTTGCTACAGCGTTGCCCAGTGCTTATCCGGAGCCCCACAGGC
CTCCTGGGCAAGATGATTAAGACTCACCAGTTCCTGTTTGGTATTGGACGTTGTCCCATT
CTGGCCACCCAAGGACCAAGTTTTTCTCAAATCCACCTTAAGGCAACCAAGGCTGGAGGG
GATTCTCCATCTTGGGCCAAGAGCCACTGTCCCTTCATGCTGTTGGAACTCCAGGATGGG
AAGAGTAAAATTGTGCAAAAAGCAGCCCCAGAAGTCCAGGAAGATGTGAAGACTTTCAAG
ACAGACTTGCCCACCTCTCTGGCCTCAACCAGCCTGAAGAAGACATTCTCCAGTCCCCAA
GAGCCAGAGAAAAATTCGGAGAAGGTCACACACCTGATTCAGAACAACATGGCTGGAGAC
CATGTCTTTGGTTATGACCAGTTTTTTAGGGACAAAATCATGGAGAAGAAACAGGACCAC
ACCTATCGTGTTTTCAAGACTGTGAATCGCTGGGCTGATGCATACCCCTTTGCTGAACAC
TTCTTTGAGGCATCTGTGGCCTCAAAGGATGTGTCTGTCTGGTGCAGTAATGACTACCTG
GGCATGAGCCGGCACCCTCGGGTCTTGCAAGCCACACAAGAGATCCTGCAGCGCCATGGA
GCTGGAGCTGGTGGCACCCGCAACATCTCGGGTACCAGTAAGTTCCATGTCGAGCTGGAG
CAAGAGCTGGCTGAGCTGCACCAGAAGGACTCAGCCCTGCTCTTCTCTTCCTGCTTTGTG
GCCAATGACTCCACTCTCTTCACCTTGGCCAAGATCTTGCCAGGGTGTGAGATTTACTCA
GATGCAGGCAACCATGCTTCCATGATCCAAGGTATCCGCAACAGTGGAGCAGCTAAGTTT
GTCTTCAGGCACAATGATCCTGACCACCTGAAGAAACTTCTAAAGAAGTCCAACCCTGAG
ACACCCAAAATCGTGGCCTTCGAGACTGTTCACTCCATGGACGGTGCCATCTGTCCCCTT
GAGGAATTGTGTGATGTGGCCCATCAGTATGGGGCTCTGACCTTCGTGGATGAAGTTCAT
GCTGTAGGACTGTATGGGTCCCGGGGTGCTGGGATTGGGGAGCGTGATGGAATTATGCAC
AAGATTGACATCATCTCTGGAACTCTTGGCAAAGCCTTTGGCTGTGTGGGTGGCTACATT
GCCAGCACCCGTGACTTGGTGGACATGGTACGTTCCTATGCTGCTGGCTTCATCTTCACC
ACTTCACTGCCTCCCATGGTGCTCTCTGGGGCTCTGGAATCCGTGCGACTGCTCAAAGGA
GAGGAGGGCCAAGCCCTGAGGAGGGCCCACCAACGCAATGTCAAGCACATGCGTCAGCTA
CTAATGGACAGGGGCCTTCCTGTCATTCCATGCCCCAGCCACATCATCCCCATTCGGGTG
GGTGATGCAATGCTGAACACCAGGATCTGTGATCTCCTGCTCTCCAAGTATGGCATCTAT
GTGCAGGCCATCAACTACCCAACTGTCCCCCGGGGTGAGGAGCTGCTGCGCTTGGCACCC
TCCCCCCACCACAGCCCTCAGATGATGGAAGACTTTGTGGAGAAGCTGCTAGAAGCCTGG
ACTGAGGTGGGACTCCCCCTCCAGGATATATCTATAGCTGCCTGCAATTTCTGCCGCCGT
CCTGTACACTTCGAGCTCATGAGTGAGTGGGAACGTTCCTACTTTGGGAACATGGGGCCC
CAGTATGTCACCACTTATGCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 587 |
| Molecular Weight
| 65137.0 |
| Theoretical pI
| 7.9 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>5-aminolevulinate synthase, erythroid-specific, mitochondrial
MVTAAMLLQRCPVLIRSPTGLLGKMIKTHQFLFGIGRCPILATQGPSFSQIHLKATKAGG
DSPSWAKSHCPFMLLELQDGKSKIVQKAAPEVQEDVKTFKTDLPTSLASTSLKKTFSSPQ
EPEKNSEKVTHLIQNNMAGDHVFGYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAEH
FFEASVASKDVSVWCSNDYLGMSRHPRVLQATQEILQRHGAGAGGTRNISGTSKFHVELE
QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
VFRHNDPDHLKKLLKKSNPETPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVH
AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
GDAMLNTRICDLLLSKYGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLEAW
TEVGLPLQDISIAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
|
| External Links |
|---|
| GenBank ID Protein
| AAI02939.1 |
| UniProtKB/Swiss-Prot ID
| Q3ZC31 |
| UniProtKB/Swiss-Prot Entry Name
| HEM0_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC102938 |
| GeneCard ID
| ALAS2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
