Showing Protein Nicotinate phosphoribosyltransferase (BMDBP00635)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00635 |
| Secondary Accession Numbers | None |
| Name | Nicotinate phosphoribosyltransferase |
| Synonyms | Not Available |
| Gene Name | NAPRT |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Coenzyme transport and metabolism |
| Specific Function | Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 14 |
| Locus | Not Available |
| SNPs | NAPRT |
| Gene Sequence |
>1602 bp ATGGCGGCGGAGCAGGACCCCGAGGGGCGCGCGGCGGCGCGGCCGCTGCTCACCGACCTG TACCAAGCCACCATGGCGCTGGGCTATTGGCGCGCCGGCCGCGCGCAGGACCAGGCCGAG TTCGAGCTCTTCTTCCGCCAGTGCCCGTTCGGCGGAGCCTTCGCCTTGGCCGCGGGACTG CGCGACTGCGTGCGTTTCCTGCGTGCCTTCCGCCTGCGGGACGCAGATGTGCAGTTCCTG GCTTCGGCGCTGCCCCCAGACACAGACCCCGCGTTCTTTGAGCACCTTCGTGCACTCGAC TGCTCTGGTGTGACGGTGCGGGCCCTGCCCGAGGGCTCCCTCGCCTTCCCCGGCGTTCCG CTACTGCAGGTGTCCGGGCCGCTCCTGGTGGTGCAGCTGCTGGAGACGCCGCTCCTCTGC CTGGTCAGCTACGCCAGCCTCATCGCCACAAATGCCGCGCGCCTTCGCCTGATCGCAGGG CCCGACAAGCGGCTGCTGGAAATGGGTCTTCGGCGTGCTCAGGGCCCCGACGGGGGTCTT ACTGCTTCTACCTACAGCTACCTGGGCGGCTTCGATGCCAGCAGCAACGTGCTCGCAGGA CAGCTAAGGGGCGTGCCGGTGGCTGGGACCCTGGCGCACTCCTTTGTCACTTCCTTTTCA GGCAGTGAGGTGCCCCCTGACCCGATGTTGGCTCCAGCGGCTGGTCAGGGCTCCCAGGTG GATCTGGCTGCCAGTGTGGAGATGTGGCTGGAGCGTGTGTGTGGCCACCTGGGGCTGGGT GTGCAAGAGCCGCATCGGGGAGAGCGGGCAGCCTTTGTGGCCTATGCCCTGGCCTTTCCC CGGGCCTTCCAGGGCCTGCTGGACACCTACAGTGTGCGGAGGAGCGGGCTCCCCAACTTC CTGGCTGTAGCCCTGGCCCTGCAGGAGCTGGGCTACCAGGCAGTGGGCGTGAGGCTGGAC AGTGGCGATCTGCTTCAGCAGGCTCGGGAGATCCGCGGGGTCTTCCGGACAGCGGCAGCC CAGTTCGGGGTGCCCTGGCTGCAGTCGGTACCCATCGCTGTCAGCAACAACATTGACGAG GAGGAGCTGGCCCGACTAGCCCAGAAGGGCAGTGAGGTGAACGTCATTGGCATCGGCACT AGCGTGGTCACCTGCCCTCGCCAGCCTTCCCTGGGCTGTGTCTACAAGCTGGTGTCTGTG GGAGGCCAGCCGCGGATGAAGCTGACCGAGGACCCCGAGAAGCAGACATTGCCTGGGAGC AAGGCTGCCTTCCGGCTCCTGGGCTCTGATGATGTGCTGCAGTTGGCAGAGGAGCCACCT CCCCAGGCTGGCCAGGAGCTGAGAGTGTGGCCTCGAGGGGCCCGGGAGTCCCGTACTGTG AGGCCGGCCCACGTGGAGCCGCTGCTGCGACTCTGGGTCCAACAGGGACAGCTGTGTGAG CCGCTGCCATCTCTGGCTGAATCCAGAGCCTTTGCCCAGCAGTCCCTGCACCGTCTGAGC CCCGCCCACAGGCGGCTGGAGCAGCCGGCACTGTACCAGGTCGCACTGTCTGAGAAGCTC CAGGCCCTGGTGGACAGACTGAGTGCCAGAGGAGCCCTCTGA |
| Protein Properties | |
| Number of Residues | 538 |
| Molecular Weight | 57871.0 |
| Theoretical pI | 7.13 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Nicotinate phosphoribosyltransferase MAAEQDPEGRAAARPLLTDLYQATMALGYWRAGRAQDQAEFELFFRQCPFGGAFALAAGL RDCVRFLRAFRLRDADVQFLASALPPDTDPAFFEHLRALDCSGVTVRALPEGSLAFPGVP LLQVSGPLLVVQLLETPLLCLVSYASLIATNAARLRLIAGPDKRLLEMGLRRAQGPDGGL TASTYSYLGGFDASSNVLAGQLRGVPVAGTLAHSFVTSFSGSEVPPDPMLAPAAGQGSQV DLAASVEMWLERVCGHLGLGVQEPHRGERAAFVAYALAFPRAFQGLLDTYSVRRSGLPNF LAVALALQELGYQAVGVRLDSGDLLQQAREIRGVFRTAAAQFGVPWLQSVPIAVSNNIDE EELARLAQKGSEVNVIGIGTSVVTCPRQPSLGCVYKLVSVGGQPRMKLTEDPEKQTLPGS KAAFRLLGSDGSLLLDVLQLAEEPPPQAGQELRVWPRGARESRTVRPAHVEPLLRLWVQQ GQLCEPLPSLAESRAFAQQSLHRLSPAHRRLEQPALYQVALSEKLQALVDRLSARGAL |
| External Links | |
| GenBank ID Protein | AAI42358.1 |
| UniProtKB/Swiss-Prot ID | A5PK51 |
| UniProtKB/Swiss-Prot Entry Name | PNCB_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC142357 |
| GeneCard ID | NAPRT |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |