Identification
BMDB Protein ID BMDBP00641
Secondary Accession Numbers None
Name Xaa-Pro aminopeptidase 1
Synonyms Not Available
Gene Name XPNPEP1
Protein Type Enzyme
Biological Properties
General Function Amino acid transport and metabolism
Specific Function Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 26
Locus Not Available
SNPs XPNPEP1
Gene Sequence
>1872 bp
ATGGCTCCAAAGATAACTTCAGAGCTGCTTCGGCAGCTGAGACAAGCCATGAGGAACTTG
GAGTATGTGACGGAACCAATCCAGGCCTACATCATCCCGTCGGGAGACGCCCATCAGAGT
GAGTACATTGCTCCGTGTGATTGTCGGCGCGCCTTTGTCTCTGGATTTGATGGCTCTGCA
GGCACAGCCATCGTCACAGAAGAACATGCGGCCATGTGGACTGACGGGCGCTACTTTCTC
CAGGCTGCCAAGCAGATGGACAGCAACTGGACACTCATGAAGATGGGTCTGAAGGACACA
CCAACTCAGGAAGACTGGCTGGTGAGTGTACTTCCTGAAGGATCCAGGGTTGGTGTAGAC
CCACTGATCATTCCTACAGATTACTGGAAGAAGATGGCCAAGGTTCTGAGAAGTGCTGGC
CACCACCTCATTCCTGTCAAGGACAACCTAGTGGACAAGATCTGGACAGACCGCCCCGAG
CGTCCCTGCAAACCGCTCATCACACTGGGCCTGGATTACACAGGCATCTCCTGGAAGGAC
AAGGTTGCAGACCTTCGGTTGAAAATGGCTGAGAGGAACGTCGTGTGGTTTGTGGTCACT
GCCCTGGATGAGATTGCGTGGCTATTCAATCTCCGAGGATCAGACGTAGAGCACAATCCT
GTATTTTTCTCCTATGCAATCTTAGGACTAGAGACGATCATGCTCTTCATTGATGGTGAC
CGCATAGACGCCCCCATTGTGAAGGAACACCTACTGCTTGACTTGGGCCTGGAAGCCGAG
TACAGAATCCAGGTGCTTCCGTACAAGTCCATCCTGAGCGAGCTCAAGATCCTGTGTGCC
AGCCTTTCCCCAAGGGAGAAGGTGTGGGTCAGTGACAAGGCCAGCTATGCTGTGAGCGAG
GCCATCCCCAAGGATCATCGCTGCTGTATGCCTTACACCCCCATCTGCATCGCCAAAGCT
GTGAAGAATTCTGCTGAATCAGAAGGCATGAGGCGAGCTCACATTAAAGATGCTGTTGCC
TTGTGTGAACTCTTTAACTGGCTGGAAAAAGAGGTGCCCAAAGGTGGTGTGACAGAGATC
TCAGCTGCCAACAAAGCTGAGGAATTCCGCAGGCAGCAGGCCGACTTTGTGGACCTGAGC
TTCCCAACCATTTCCAGTACGGGACCCAATGGCGCCATCATTCACTACGCGCCGGTCCCT
GAGACGAATAGGACCTTGTCTCTGGATGAGGTGTACCTCATTGACTCGGGTGCTCAATAC
AAGGACGGAACCACAGACGTCACCCGCACCATGCATTTTGGAACTCCTACAGCTTACGAG
AAGGAATGCTTCACATACGTCCTCAAGGGCCACATAGCTGTGAGCGCAGCGGTTTTCCCG
ACTGGAACCAAAGGCCACCTCCTTGACTCCTTTGCCCGCTCAGCGTTATGGGATTCTGGC
CTGGATTACCTGCATGGAACGGGGCATGGTGTTGGGTCTTTTCTGAATGTTCATGAGGGT
CCATGTGGCATCAGTTATAAAACATTCTCTGATGAGCCCTTGGAGGCCGGCATGATCGTC
ACTGATGAGCCAGGGTATTATGAAGATGGGGCTTTTGGAATTCGCATTGAGAATGTTGTC
CTGGTGGTGCCTGTTAAGACCAAGTATAACTTCAACAACCGGGGAAGCCTGACCTTTGAA
CCTCTGACTTTGGTTCCAATACAGACCAAAATGATAGATGTGGATTCTCTAACAGACAAA
GAGTGTGACTGGCTCAACAGCTACCACCTGACCTGCAGGGACGTGATCGGGAAGGAGCTG
CAAAAGCAGGGCCGCCAGGAAGCCCTCGAGTGGCTCATCAGAGAGACGCAGCCCATCTCC
AAACAGCCTTAA
Protein Properties
Number of Residues 623
Molecular Weight 69790.0
Theoretical pI 5.41
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Xaa-Pro aminopeptidase 1
MAPKITSELLRQLRQAMRNLEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA
GTAIVTEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD
PLIIPTDYWKKMAKVLRSAGHHLIPVKDNLVDKIWTDRPERPCKPLITLGLDYTGISWKD
KVADLRLKMAERNVVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAILGLETIMLFIDGD
RIDAPIVKEHLLLDLGLEAEYRIQVLPYKSILSELKILCASLSPREKVWVSDKASYAVSE
AIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI
SAANKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQY
KDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG
LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV
LVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNSYHLTCRDVIGKEL
QKQGRQEALEWLIRETQPISKQP
GenBank ID Protein ABF57317.1
UniProtKB/Swiss-Prot ID Q1JPJ2
UniProtKB/Swiss-Prot Entry Name XPP1_BOVIN
PDB IDs Not Available
GenBank Gene ID BT025361
GeneCard ID XPNPEP1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available