Showing Protein Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (BMDBP00651)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00651 |
| Secondary Accession Numbers | None |
| Name | Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 |
| Synonyms | Not Available |
| Gene Name | POMGNT1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in alpha-1,3-mannosylglycoprotein 2-beta-N-ace |
| Specific Function | Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose. |
| Pathways |
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| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | POMGNT1 |
| Gene Sequence |
>1983 bp ATGGACGACTGGAAGCCCAGCCCCCTCATCAAGCCCTTTGGGGCGCGAAAAAAGCGGAGC TGGTATCTTACCTGGAAGTATAAACTGACCAACCAGCGGGCCCTGCGGAGGTTCTGTCAG ACAGGAGCCGTGCTTTTCCTACTGGTGACCGTCATTGTCAACATCAAGTTGATCCTGGAC ACACGACGAGCTATCAGCGAGGCCAGTGAAGACCTGGAGCCAGAACAAGACTATGATGAG GCCCTGGGCCGATTGGAGCCTCCACGGCGCATAGGCAGTGGTCCCCGACGTGTCCTGGAT GTGGAGGTATACTCAAGCCGCAGCAAAGTGTATGTGGCAGTGGACGGCACCACGGTGCTG GAGGATGAGGCCCAGGAGCAGGGCCGGGGCATCCACGTCATCGTCCTCAACCAGGCCACG GGCCATGTGATGGCAAAGCGAGTGTTTGACACCTATTCACCTCATGAGGATGAGGCCATG GTGCTGTTCCTCAACATGGTGGCACCTGGCCGAGTGCTCATCTGCACCGTCAAGGACGAG GGCTCCTTCCACCTCAAGGACACCGCCAAGGCTCTGCTGAGGAGCCTAGGCAGCCAGGCT GGCCCTGCCCTGGGCTGGAGAGACACCTGGGCCTTCGTGGGACGAAAAGGAGGTCCTGTG CTCGGGGAGAAACATTCTAAGTCACCTGCCCTCTCCTCCTGGGGGGATCCAGTTCTGCTG AAGACAGATGTGCCGCTGAGCTCAGCTGAAGAGGCAGAGTGCCACTGGGCAGACACAGAG CTGAACCGTCGCCGCCGCCGCTTCTGCAGCAAAGTTGAGGGCTATGGGAGCGTGTGCAGC TGCAAGGACCCCACACCCATCGAGTTCAGCCCTGACCCACTCCCAGACAACAAGGTCCTC AATGTGCCTGTGGCTGTCATTGCAGGGAACCGGCCCAATTACCTGTACAGGATGCTGCGC TCTCTACTCTCAGCCCAGGGGGTGTCTCCCCAGATGATAACAGTTTTCATCGATGGCTAC TATGAGGAGCCGATGGATGTGGTGGCGCTGTTTGGTCTGAGGGGCATCCAGCACACTCCC ATCAGCATCAAGAACGCCCGTGTGTCTCAGCACTACAAGGCCAGCCTCACTGCCACTTTC AACCTGTTTCCGGAAGCCAAGTTTGCTGTGGTTCTGGAAGAGGACCTGGACATTGCTGTG GATTTTTTCAGTTTCCTGAGCCAATCCATCCACCTGCTGGAGGAGGACGACAGCTTGTAC TGTATCTCTGCCTGGAATGACCAGGGCTATGAGCACACGGCAGAGGACCCAGCACTGCTA TACCGTGTGGAGACCATGCCTGGGCTGGGCTGGGTGCTCAGGAAGTCCTTGTACAAGGAG GAGCTTGAACCCAAGTGGCCCACACCAGAAAAGCTCTGGGACTGGGACATGTGGATGCGG ATGCCGGAACAACGCCGAGGCCGAGAATGCATTATCCCTGACGTGTCCCGATCCTACCAC TTCGGCATCGTTGGCCTCAACATGAATGGCTACTTCCATGAGGCCTACTTCAAGAAGCAC AAGTTCAACACGGTTCCAGGTGTCCAGCTCAGGAACGTGGACAGTCTGAAGAAGGATGCT TATGAAGTGGAAGTTCACAGGCTGCTCAGCGAAGCAGAGGTTCTGGACCACAGCAAGAAC CCTTGTGAAGACTCTTTCCTGCCAGACACAGAGGGCCACACCTACGTGGCCTTTATCCGG ATGGAGAAGGACGATGACTTCACCACCTGGACTCAGCTTGCCAAGTGCCTCCGAATCTGG GACCTGGATGTGCGTGGCAACCACCGGGGCCTGTGGAGACTGTTTCGGAAGAAGAACCAC TTCCTGGTGGTGGGGGTCCCAGCCTCCCCGTACTCGATGAAGAAGCCACCATCAATCACC CCAATTTTCTTGGAGTCACCCCCAAAGGAGGAGGGAGGCCCAGGAGCTGCAGAACAGACA TGA |
| Protein Properties | |
| Number of Residues | 660 |
| Molecular Weight | 75077.0 |
| Theoretical pI | 6.7 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILD TRRAISEASEDLEPEQDYDEALGRLEPPRRIGSGPRRVLDVEVYSSRSKVYVAVDGTTVL EDEAQEQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDE GSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLL KTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVL NVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTP ISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLY CISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMR MPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKDA YEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLRIW DLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSMKKPPSITPIFLESPPKEEGGPGAAEQT |
| External Links | |
| GenBank ID Protein | AAX08670.1 |
| UniProtKB/Swiss-Prot ID | Q5EAB6 |
| UniProtKB/Swiss-Prot Entry Name | PMGT1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BT020653 |
| GeneCard ID | POMGNT1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |