Showing Protein 5,6-dihydroxyindole-2-carboxylic acid oxidase (BMDBP00664)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00664 | ||
| Secondary Accession Numbers | None | ||
| Name | 5,6-dihydroxyindole-2-carboxylic acid oxidase | ||
| Synonyms | Not Available | ||
| Gene Name | TYRP1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Involved in copper ion binding | ||
| Specific Function | Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. | ||
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 8 | ||
| Locus | Not Available | ||
| SNPs | TYRP1 | ||
| Gene Sequence |
>1614 bp ATGAAATCTCCTACACTCCTCTCTCTGGGTTACATGTTCCTAGTCCTGCTTTTTTTCCAG CAGGCCTGGGCTCAGTTCCCAAGAGAGTGTGCTACCATTGAGGCTTTGAGGAATGGCGTG TGTTGCCCAGACCTGTCCCCACTGTCTGGGCCTGGGTCTGACCGCTGCGGTCTCTCATCA GGGAGGGGCAGATGTGAGGTGGTGATAGCCGACTCCCGGCCCCACAGCCACCACTACCCG CACGATGGCAGAGATGACCGAGAGGGCTGGCCCACACGCTCCTTCAACAGGACATGCCAC TGCAATGGCAATTTCTCAGGACACAACTGTGGAACCTGCCGCCCTGGCTGGGGAGGGGCT GCCTGTGACCAGAGGGTTCTCACAGTCAGGAGAAACCTTCTGGACTTAAGCACAGAAGAA AAGAACCGCTTTGTCCGGGCCCTGGATATGGCAAAGCGCACCACTCACCCTCAGTTTGTC ATTGCCACAAGGAGGTCAGAAGAAATACTGGGGCCAGATGGCAACACACCGCAGTTTGAG AACATTTCCATTTATAACTACTTCGTTTGGACACACTACTACTCAGTCAAAAAGACTTTC TTGGGAGCAGGACAGGAAAGCTTTGGTGAGGTGGATTTCTCTCACGAGGGACCAGCATTT CTCACCTGGCACAGGTACCACCTGCTGCAGCTGGAGAGAGACATGCAGGAAATGTTGCAG GATCCTTCTTTCTCCCTCCCTTACTGGAATTTTGCCACTGGGAAGAACACCTGCGACATT TGCACCGATGACTTGATGGGATCAAGAAGCAACTTTGATTCCACTCTTATAAGCCCGAAC TCTGTCTTTTCTCAATGGCGAGTGGTCTGCGAATCCTTGGAAGATTATGATACCCTGGGA ACCCTTTGCAACAGCACTGAGGGTGGGCCAATTAAGAGAAACCCAGCTGGAAATGTGGCC AGGCCAATGGTGCAACGTCTTCCTAAACCACAGGATGTCGCGCAGTGCTTGGAAGTTGGT TCATATGACACACCTCCTTTTTATTCTAATTCTACAAACAGCTTCCGAAACACAGTGGAA GGTTACAGTCATCCCACAGGAAGGTATGACCCTGCTGTGCGAAGCCTTCACAATTTGGCT CATCTATTCCTGAATGGAACAGGGGGACAAACTCATTTATCTCCCAATGATCCTATTTTT GTCCTCCTACATACATTCACTGATGCAGTATTTGATGAATGGCTGAGGCGATACAATGCT GATATATCCACATATCCACTGGAAAATGCCCCTATTGGACATAACAGACAATACAATATG GTACCATTTTGGCCTCCAGTTACCAACATAGAAATGTTTGTTACTGCTCCAGACAACCTG GGCTATACTTACGAAGTTCAATGGCCAAGTCGGAGTTTTAGCATTTCTGAGATTGTCACC ATAGCAGTAGTGGCTGCATTATCACTGGTTGCGGTCATTTTTGCGGGCGCTTCTTGTCTG ATTCGTGCCAGAAGCAACATGGATGAAGCAAATCAGCCTCTCCTTACTGATCAGTATCAA CACTACATTGAAGAATATGAAAAAATCCATAATCCTAACCAGTCTGTGGTCTAG |
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| Protein Properties | |||
| Number of Residues | 537 | ||
| Molecular Weight | 60617.0 | ||
| Theoretical pI | 6.19 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>5,6-dihydroxyindole-2-carboxylic acid oxidase MKSPTLLSLGYMFLVLLFFQQAWAQFPRECATIEALRNGVCCPDLSPLSGPGSDRCGLSS GRGRCEVVIADSRPHSHHYPHDGRDDREGWPTRSFNRTCHCNGNFSGHNCGTCRPGWGGA ACDQRVLTVRRNLLDLSTEEKNRFVRALDMAKRTTHPQFVIATRRSEEILGPDGNTPQFE NISIYNYFVWTHYYSVKKTFLGAGQESFGEVDFSHEGPAFLTWHRYHLLQLERDMQEMLQ DPSFSLPYWNFATGKNTCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCESLEDYDTLG TLCNSTEGGPIKRNPAGNVARPMVQRLPKPQDVAQCLEVGSYDTPPFYSNSTNSFRNTVE GYSHPTGRYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNA DISTYPLENAPIGHNRQYNMVPFWPPVTNIEMFVTAPDNLGYTYEVQWPSRSFSISEIVT IAVVAALSLVAVIFAGASCLIRARSNMDEANQPLLTDQYQHYIEEYEKIHNPNQSVV |
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| External Links | |||
| GenBank ID Protein | AAL38167.2 | ||
| UniProtKB/Swiss-Prot ID | Q8WN57 | ||
| UniProtKB/Swiss-Prot Entry Name | TYRP1_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | AF445638 | ||
| GeneCard ID | TYRP1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||