Identification
BMDB Protein ID BMDBP00671
Secondary Accession Numbers None
Name Ferritin heavy chain
Synonyms Not Available
Gene Name FTH1
Protein Type Enzyme
Biological Properties
General Function Inorganic ion transport and metabolism
Specific Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 29
Locus Not Available
SNPs FTH1
Gene Sequence
>546 bp
ATGACGACCGCATCCCCCTCGCAGGTGCGCCAGAACTACCACCAGGACTCGGAGGCCGCC
ATCAACCGCCAGATCAACCTGGAGCTCTACGCCTCCTATGTCTACCTGTCCATGTCGTAC
TATTTTGACCGTGATGATGTGGCTTTGAAGAACTTTGCCAAATACTTTCTTCACCAATCT
CATGAGGAGAGGGAACATGCTGAGAGACTGATGAAGCTGCAGAACCAGCGAGGCGGCCGA
ATCTTCCTTCAGGATATCAAGAAACCAGACCGTGATGACTGGGAGAATGGGCTGACTGCA
ATGGAATGTGCGCTGTGCTTGGAGAGAAGTGTGAATCAGTCACTACTGGAACTGCACAAA
CTGGCCACTGAAAAAAATGATCCCCATCTGTGTGATTTCATTGAGACTCATTACCTGAAT
GAGCAGGTGGAAGCCATCAAAGAATTGGGTGACCACATAACCAACCTGCGCAAGATGGGG
GCCCCTGGATCTGGCATGGCAGAGTACCTCTTTGACAAGCACACCCTGGGACACAGTGAG
AGCTAA
Protein Properties
Number of Residues 181
Molecular Weight 21052.0
Theoretical pI 5.76
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Ferritin heavy chain
MTTASPSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
HEEREHAERLMKLQNQRGGRIFLQDIKKPDRDDWENGLTAMECALCLERSVNQSLLELHK
LATEKNDPHLCDFIETHYLNEQVEAIKELGDHITNLRKMGAPGSGMAEYLFDKHTLGHSE
S
GenBank ID Protein BAA24818.1
UniProtKB/Swiss-Prot ID O46414
UniProtKB/Swiss-Prot Entry Name FRIH_BOVIN
PDB IDs
GenBank Gene ID AB003093
GeneCard ID FTH1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available