Showing Protein Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (BMDBP00682)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00682 |
| Secondary Accession Numbers | None |
| Name | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 |
| Synonyms | Not Available |
| Gene Name | PLOD1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in iron ion binding |
| Specific Function | Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (By similarity). These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 16 |
| Locus | Not Available |
| SNPs | PLOD1 |
| Gene Sequence |
>2181 bp ATGCGGCTCCTGCTGCTCCTGGCCCCGTTGGGCTGGCTGCTTCTAGCCGAAACGAAGGGT GACGCCAAGCCGGAGGACAACCTTTTGGTCCTCACTGTGGCTACGAAGGAGACCGAGGGG TTCCGACGCTTTAAGCGCTCAGCTCAGTTCTTCAACTACAAGATCCAGGCGCTGGGGCTG GGGGAGGACTGGCCTGGGGAGGCGATGTTGGCAGGCGGTGGGCTGAAGGTCCGGCTATTG AAGAAAGCCCTGGAGAAGCACGCCGACAAGGAGAACCTGGTCATTCTCTTCACAGACAGC TATGATGTGGTATTTGCCTCGGGGCCCCGAGAGCTCCTGAAGAAGTTCCGGCAGGCCAGG AGCCAGGTGGTCTTCTCGGCCGAGGAGCTCATCTACCCGGACCGCAGGCTGGAGGCCAAT TACCCGGTGGTGTCCGACGGCAAGAGGTTCCTGGGCTCTGGAGGCTTCATCGGTTATGCT CCCAACCTTATCAAACTGGTGGCAGAGTGGGAAGGCCAGGACAGCGACAGCGATCAGCTC TTTTACACCAAGATCTTCTTGGACCCAGAGAAGAGGGAGCAGATCAATATCACCCTGGAC CACCGTTGCCGAATCTTCCAGAATTTCCATGGAGCCTTGGATGAGGTCGTGCTCAAGTTT GAAATGGGCCAAGTGAGAGCGAGGAACCTGGCCTACGACACCCTCCCAGTCCTGATTCAT GGCAACGGGCCCACCAAGCTGCAGCTGAACTACTTGGGCAACTACATCCCGCGCTTCTGG ACCTTCGAGACGGGGTGCGCTGTGTGTGACGAGGGCCTGCGCAGCCTCAAGGGCATCGGG GATGAAGCTCTGCCTGCTGTTCTGGTCGGCGTGTTCATCGAACAGCCCACCCCGTTCCTG TCCCTGTTCTTCCAGCGGCTCTTGCTCCTCCACTACCCCCAAAAACGGTTCAGGCTTTTC ATTCACAACCACGAGCAGCACCACAAGGCTCAGGTGGAGCAGTTCCTGGCAGAGCACGGC GATGAGTACCAGTCTGTGAAACTGGTGGGCCCCGAGGTGCGGGTGGCCAACGCAGACGCC AGGAACATGGGCGCGGACTTGTGCCGGCAGGACCGTGGCTGCACTTACTACTTCAGCGTG GATGCCGACGTGGCCCTGACTGAGCCCAAAACCCTGCGGCTGCTGATCGAGCAGAACAAG AACGTTATCACCCCATTGATGACCCGCCATGGGAGGCTGTGGTCGAACTTCTGGGGGGCA CTGAGTGCAGATGGCTACTACGCCCGCTCCGAGGACTACGTGGACATCGTGCAGGGGCGG CGTGTGGGTGTCTGGAATGTACCCTACATCTCAAACATCTACCTGATCAAGGGTAGCGCC CTGCGGGCTGAGTTGCAGGAGACAGACCTGTTCCACCACAGCAAGCTGGACCCCGACATG GCCTTCTGTGCCAACATCCGGCAGCAGGATGTGTTCATGTTCCTGACCAACCGGCACTCC TTTGGCCACCTGCTCTCCCTGGACAGCTACCAGACCACCCACCTCCACAACGACCTCTGG GAGGTGTTCAGCAACCCCGAGGACTGGAAGGAGAAATACATCCATGAGAACTACACCAAG GCCTTGGCGGGGAAGATGGTGGAGATGCCTTGCCCGGACGTCTACTGGTTCCCCATCTTC ACGGAGACGGCCTGTGATGAGCTGGTGGAAGAGATGGAGCACTACGGCCAGTGGTCCCTG GGAGATAACAAGGACAACCGCATCCAGGGTGGCTACGAAAACGTGCCAACCATCGACATC CACATGAACCAGATCAACTATGAGCGGGAGTGGCACAAGTTCCTGGTGGAGTACATCGCC CCCATGACGGAGAAACTCTACCCGGGCTACTACACCAGGGCCCAATTCGACCTGGCCTTT GTCGTCCGCTACAAGCCTGATGAGCAGCCCTCGCTGGTGCCACACCACGACGCCTCCACC TTCACCATCAACATCGGCCTGAACCGGGTTGGAGTGGATTATGAGGGCGGGGGGTGTCGG TTCCTGCGCTACAACTGCTCCATCCGAGCCCCACGGAAGGGCTGGACCCTGATGCACCCC GGGCGACTCACGCACTACCACGAGGGGGTCCCCACCACCAAAGGCACCCGCTACATCGCA GTCTCCTTCGTCGATCCCTAA |
| Protein Properties | |
| Number of Residues | 726 |
| Molecular Weight | 83487.0 |
| Theoretical pI | 6.61 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 MRLLLLLAPLGWLLLAETKGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGL GEDWPGEAMLAGGGLKVRLLKKALEKHADKENLVILFTDSYDVVFASGPRELLKKFRQAR SQVVFSAEELIYPDRRLEAKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQL FYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGQVRARNLAYDTLPVLIH GNGPTKLQLNYLGNYIPRFWTFETGCAVCDEGLRSLKGIGDEALPAVLVGVFIEQPTPFL SLFFQRLLRLHYPQKRLRLFIHNHEQHHKAQVEQFLAEHGDEYQSVKLVGPEVRVANADA RNMGADLCRQDRGCTYYFSVDADVALTEPKTLRLLIEQNKNVIAPLMTRHGRLWSNFWGA LSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELQETDLFHHSKLDPDM AFCANIRQQDVFMFLTNRHSFGHLLSLDSYQTTHLHNDLWEVFSNPEDWKEKYIHENYTK ALAGKMVEMPCPDVYWFPIFTETACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDI HMNQINFEREWHKFLVEYIAPMTEKLYPGYYTRAQFDLAFVVRYKPDEQPSLVPHHDAST FTINIALNRVGVDYEGGGCRFLRYNCSIRAPRKGWTLMHPGRLTHYHEGLPTTKGTRYIA VSFVDP |
| External Links | |
| GenBank ID Protein | AAC25107.1 |
| UniProtKB/Swiss-Prot ID | O77588 |
| UniProtKB/Swiss-Prot Entry Name | PLOD1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF054274 |
| GeneCard ID | PLOD1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |