Showing Protein Dihydropyrimidine dehydrogenase [NADP(+)] (BMDBP00689)
| Identification | |||||||
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| BMDB Protein ID | BMDBP00689 | ||||||
| Secondary Accession Numbers |
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| Name | Dihydropyrimidine dehydrogenase [NADP(+)] | ||||||
| Synonyms | Not Available | ||||||
| Gene Name | DPYD | ||||||
| Protein Type | Enzyme | ||||||
| Biological Properties | |||||||
| General Function | Amino acid transport and metabolism | ||||||
| Specific Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. | ||||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||||
| Cellular Location | Not Available | ||||||
| Gene Properties | |||||||
| Chromosome Location | 3 | ||||||
| Locus | Not Available | ||||||
| SNPs | DPYD | ||||||
| Gene Sequence |
>3078 bp ATGGCCCCTGTGCTAAGCAAGGACGTGGCGGATATCGAGAGTATCCTGGCTTTAAATCCT CGAACACAGTCTCGTGCAACTCTGCGTTCCACTTTGGCCAAGAAATTAGACAAGAAACAT TGGAAAAGAAATCCTGATAAGAACTGCTTTAATTGCGAGAAGCTGGAGAATAATTTTGAT GACATCAAGCACACGACTCTTGGTGAGCGAGGAGCTCTCCGAGAAGCAATGAGATGCCTG AAATGTGCAGATGCCCCCTGTCAGAAGAGCTGTCCAACAAATCTAGATATCAAATCGTTC ATCACAAGTATCTCAAACAAGAACTATTATGGAGCTGCTAAGATGATATTTTCTGACAAC CCACTTGGTCTGACCTGTGGAATGGTATGCCCCACCTCTGATCTTTGTGTAGGTGGATGT AATTTGTATGCCACTGAAGAGGGACCAATTAATATTGGTGGATTGCAGCAATATGCTACT GAGGTATTCAAAGCAATGAATATCCCACAAATCAGGAATCCTTCTCTGCCTCCCCCAGAA AAAATGCCTGAAGCCTATTCTGCAAAGATTGCTCTTTTGGGTGCTGGGCCTGCAAGTATA AGTTGTGCTTCGTTCTTGGCTCGATTAGGCTACAATGACATCACTATATTTGAAAAACAA GAATACGTTGGTGGTATAAGTACTTCTGAAATCCCTCAGTTCCGGCTGCCATATGATGTA GTAAATTTTGAGATTGAGCTTATGAAGGACCTTGGTGTAAAGATAATTTGTGGTAAAAGC CTTTCAGTGAATGACATTACTCTTAGTACTTTGAAAGAAGAAGGGTACAAAGCTGCTTTC ATTGGGATAGGTTTGCCAGAACCCAAGAAGGATCACATCTTCCAAGGCCTGACACAGGAC CAGGGGTTTTACACTTCCAAAGACTTTCTGCCTCTTGTAGCCAAAAGCAGTAAAGCAGGA ATGTGCGCCTGTCACTCTCCATTGCTGTCGATACGGGGAACCGTGATTGTACTCGGAGCT GGAGACACAGCTTTCGACTGTGCAACATCCGCTTTACGTTGTGGAGCCCGCCGAGTGTTC ATCGTCTTCAGAAAAGGCTTTGTTAATATAAGAGCTGTCCCTGAGGAGGTGGAGCTTGCT AGAGAAGAAAAATGTGAATTTTTGCCTTTCTTGTCTCCACGGAAGGTTATAGTAAAAGGT GGGAGAATTGTTGCCATGCAATTTGTTCGGACAGAGCAAGATGAAACTGGAAAATGGAAT GAAGATGGAGATCAGATAGCCTGTCTGAAAGCCGATGTGGTCATCAGTGCCTTTGGCTCA GTTCTGAGTGATCCTAAAGTAAAAGAAGCCTTGAGCCCTATAAAATTTAACAGATGGGAT CTCCCAGAAGTAGATCCAGAAACTATGCAAACCAGTGAGCCATGGGTGTTTGCAGGTGGT GATGTGGTTGGTATAGCCAACACTACAGTGGAAGCCGTGAATGATGGAAAGCAAGCCTCT TGGTACATTCACAGATATATACAGTCACAATATGGAGCTTCAGTTTCTGCTAAGCCCGAA CTCCCCCTGTTTTATACTCCCATTGATCTGGTGGACATTAGTGTGGAAATGGCTGCATTG AAGTTTACAAATCCTTTTGGTCTTGCCAGTGCAACTCCAACTACCAGTTCGTCAATGATT CGAAGAGCTTTTGAAGCTGGATGGGCCTTTGCTCTGACCAAAACTTTCTCTCTTGATAAG GATATAGTGACAAATGTTTCACCCAGAATCATCCGGGGGACCACCTCTGGCCCCATGTAT GGCCCTGGACAAAGCTCTTTCCTGAATATTGAGCTCATCAGTGAAAAAACGGCTGCATAT TGGTGTCAAAGTGTCACTGAACTAAAAGCCGACTTTCCAGACAATATTGTGATTGCTAGC ATCATGTGCAGTTACAACAGAAATGACTGGATGGAACTCTCCAGAAAGGCTGAGGCTTCT GGAGCAGACGCCCTGGAGTTAAATTTATCGTGTCCGCATGGCATGGGAGAAAGAGGAATG GGTCTGGCTTGTGGACAGGATCCAGAGCTGGTGCGGAACATCTGTCGCTGGGTTAGGCAA GCTGTTCGGATTCCTTTTTTTGCCAAGTTGACCCCAAATGTCACTGATATTGTAAGCATA GCCAGAGCTGCAAAGGAAGGTGGGGCAAATGGTGTTACAGCTACCAACACTGTCTCAGGT CTCATGGGATTAAAAGCTGATGGCACACCCTGGCCAGCAGTGGGCCGTGAGAAGCGGACT ACATACGGCGGAGTGTCCGGCACAGCCATCAGACCTATTGCTTTGAGAGCTGTGACCACC ATTGCTCGTGCTTTGCCTGAATTTCCCATTTTGGCCACTGGTGGAATTGACTCAGCTGAA AGTGGTCTTCAGTTTCTCCACGGTGGTGCTTCGGTGCTCCAGGTATGCAGTGCTATTCAA AATCAGGATTTCACTATCATCCAAGACTACTGCACTGGCCTCAAAGCCTTGCTTTATCTG AAAAGCATTGAAGAACTACAGGACTGGGATGGGCAGAGTCCAGCCACGAAGAGTCACCAG AAAGGGAAACCAGTCCCTTGTATTGCTGAACTTGTGGGAAAGAAACTGCCAAGCTTTGGA CCTTATCTTGAGAAGTGCAAGAAAATCATAGCAGAGGAAAAGTTGAGACTGAAAAAAGAA AATGTGACCGTTCTACCACTTGAAAGAAACCATTTTATCCCAAAAAAACCTATTCCTTCT GTTAAGGATGTGATTGGAAAAGCTCTGCAGTACCTTGGAACATATGGTGAACTGAACAAC ACAGAGCAGGTTGTGGCTGTGATCGATGAAGAGATGTGTATCAACTGTGGCAAATGCTAC ATGACCTGTAATGACTCTGGCTACCAGGCTATCCAGTTTGATCCTGAAACCCACCTGCCC ACCGTTACTGACACTTGTACAGGCTGTACCCTGTGTCTCTCCGTCTGCCCTATTATCGAC TGCATCAAAATGGTTTCCAGGACAACACCTTATGAACCAAAGAGAGGCTTGCCCTTGGCT GTGAATCCTGTGTCTTAA |
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| Protein Properties | |||||||
| Number of Residues | 1025 | ||||||
| Molecular Weight | 111697.0 | ||||||
| Theoretical pI | 7.32 | ||||||
| Pfam Domain Function | Not Available | ||||||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Dihydropyrimidine dehydrogenase [NADP+] MAPVLSKDVADIESILALNPRTQSRATLRSTLAKKLDKKHWKRNPDKNCFNCEKLENNFD DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSISNKNYYGAAKMIFSDN PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQYATEVFKAMNIPQIRNPSLPPPE KMPEAYSAKIALLGAGPASISCASFLARLGYNDITIFEKQEYVGGISTSEIPQFRLPYDV VNFEIELMKDLGVKIICGKSLSVNDITLSTLKEEGYKAAFIGIGLPEPKKDHIFQGLTQD QGFYTSKDFLPLVAKSSKAGMCACHSPLLSIRGTVIVLGAGDTAFDCATSALRCGARRVF IVFRKGFVNIRAVPEEVELAREEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWN EDGDQIACLKADVVISAFGSVLSDPKVKEALSPIKFNRWDLPEVDPETMQTSEPWVFAGG DVVGIANTTVEAVNDGKQASWYIHRYIQSQYGASVSAKPELPLFYTPIDLVDISVEMAAL KFTNPFGLASATPTTSSSMIRRAFEAGWAFALTKTFSLDKDIVTNVSPRIIRGTTSGPMY GPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNRNDWMELSRKAEAS GADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRIPFFAKLTPNVTDIVSI ARAAKEGGANGVTATNTVSGLMGLKADGTPWPAVGREKRTTYGGVSGTAIRPIALRAVTT IARALPEFPILATGGIDSAESGLQFLHGGASVLQVCSAIQNQDFTIIQDYCTGLKALLYL KSIEELQDWDGQSPATKSHQKGKPVPCIAELVGKKLPSFGPYLEKCKKIIAEEKLRLKKE NVTVLPLERNHFIPKKPIPSVKDVIGKALQYLGTYGELNNTEQVVAVIDEEMCINCGKCY MTCNDSGYQAIQFDPETHLPTVTDTCTGCTLCLSVCPIIDCIKMVSRTTPYEPKRGLPLA VNPVS |
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| External Links | |||||||
| GenBank ID Protein | AAB40985.1 | ||||||
| UniProtKB/Swiss-Prot ID | Q28007 | ||||||
| UniProtKB/Swiss-Prot Entry Name | DPYD_BOVIN | ||||||
| PDB IDs | |||||||
| GenBank Gene ID | U20981 | ||||||
| GeneCard ID | DPYD | ||||||
| GenAtlas ID | Not Available | ||||||
| HGNC ID | Not Available | ||||||
| References | |||||||
| General References | Not Available | ||||||