Showing Protein V-type proton ATPase subunit d 1 (BMDBP00724)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00724 |
| Secondary Accession Numbers | None |
| Name | V-type proton ATPase subunit d 1 |
| Synonyms | Not Available |
| Gene Name | ATP6V0D1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Energy production and conversion |
| Specific Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 18 |
| Locus | Not Available |
| SNPs | ATP6V0D1 |
| Gene Sequence |
>1056 bp ATGTCGTTCTTCCCGGAGCTTTACTTCAACGTGGACAATGGCTACTTGGAGGGACTGGTG CGCGGCCTGAAGGCTGGGGTGCTCAGCCAGGCGGACTACCTCAACCTGGTGCAGTGCGAG ACGCTCGAGGACCTGAAGCTGCACCTGCAGAGCACTGACTATGGCAACTTCCTGGCCAAT GAGGCTTCGCCACTGACAGTGTCCGTCATTGATGACCGGCTCAAGGAGAAGATGGTGGTG GAGTTCCGTCACATGAGGAACCATGCGTATGAGCCACTCGCCAGCTTCCTGGACTTCATT ACTTACAGCTACATGATCGACAACGTAATCCTGCTCATCACGGGCACGCTGCACCAGCGC TCTATCGCCGAGCTTGTGCCTAAGTGCCACCCGCTTGGCAGTTTCGAGCAGATGGAGGCC GTGAACATCGCACAGACACCCGCCGAGCTCTACAATGCTATTCTGGTGGACACGCCCCTG GCGGCTTTTTTCCAGGACTGCATCTCAGAGCAGGACCTCGATGAGATGAACATCGAGATC ATCCGCAACACGCTGTACAAGGCCTACCTGGAGTCCTTCTACAAGTTCTGCACCCTGCTG GGCGGGACCACGGCCGACGCCATGTGCCCCATCCTGGAGTTTGAAGCAGACCGCCGCGCC TTCATCATCACCATTAACTCCTTCGGCACAGAGCTGTCCAAGGAGGACCGTGCCAAGCTC TTCCCGCACTGTGGACGGCTCTACCCGGAGGGCCTGGCCCAGCTGGCTCGAGCCGACGAC TATGAGCAGGTCAAGAACGTGGCCGACTACTACCCGGAGTACAAGCTGCTTTTCGAAGGT GCGGGCAGCAACCCTGGAGACAAGACCCTGGAGGACCGATTCTTCGAGCACGAGGTGAAA CTGAACAAGTTGGCCTTTCTGAACCAGTTCCACTTTGGTGTTTTCTATGCCTTTGTGAAG CTCAAGGAGCAGGAGTGTCGCAACATTGTGTGGATTGCCGAGTGCATCGCCCAACGCCAC CGGGCCAAGATTGACAACTACATCCCTATCTTCTAG |
| Protein Properties | |
| Number of Residues | 351 |
| Molecular Weight | 40329.0 |
| Theoretical pI | 4.63 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>V-type proton ATPase subunit d 1 MSFFPELYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLAN EASPLTVSVIDDRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQR SIAELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEI IRNTLYKAYLESFYKFCTLLGGTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKL FPHCGRLYPEGLAQLARADDYEQVKNVADYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVK LNKLAFLNQFHFGVFYAFVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF |
| External Links | |
| GenBank ID Protein | AAA64520.1 |
| UniProtKB/Swiss-Prot ID | P61420 |
| UniProtKB/Swiss-Prot Entry Name | VA0D1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | J04204 |
| GeneCard ID | ATP6V0D1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |